Results 51 to 60 of about 61,250 (205)

Dual Inhibition of Mast Cells and Thymic Stromal Lymphopoietin Using a Novel Bispecific Antibody, CDX‐622

open access: yesAllergy, EarlyView.
SCF and TSLP expression are known to drive unique immune responses leading to the onset of allergic and inflammatory diseases. Here, we describe the characterization of a novel bsAb, CDX‐622, that targets SCF and TSLP. CDX‐622 inhibits MC functions through SCF starvation and Type 2 inflammatory responses via TSLP inhibition.
Michael B. Murphy   +17 more
wiley   +1 more source

Single versus bilateral lung transplantation for idiopathic pulmonary fibrosis [PDF]

open access: bronze, 2000
Bryan F. Meyers   +5 more
openalex   +1 more source

Antimicrobial prescribing guidelines for horses in Australia

open access: yesAustralian Veterinary Journal, EarlyView.
The growing problem of antimicrobial resistance also affects equine veterinarians with increasing frequency. Antimicrobial stewardship and responsible prescribing are essential for a future in which effective antimicrobials are available, as it is unlikely that new antimicrobials will become available for use in horses.
L Hardefeldt   +18 more
wiley   +1 more source

Human hypoxia models in aerospace medicine: Potential applications for human pharmacological research

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aerospace medicine required controlled terrestrial models to investigate influences of altered atmosphere conditions, such as hypoxia, on human health and performance. These models could potentially be expanded to encompass disease conditions or treatment targets regulated through hypoxia or hypercapnia.
Titiaan E. Post   +4 more
wiley   +1 more source

Respiratory muscle strength and gas exhange in neuromuscular diseases: Comparison with chronic pulmonary emphysema and idiopathic pulmonary fibrosis.

open access: bronze, 1989
Yoshihiro Nishimura   +6 more
openalex   +2 more sources

The functions of the logical mirror operator in the processing of organ transplantation

open access: yesBritish Journal of Psychotherapy, EarlyView.
Abstract Organ transplantation is a complex psychodynamic process. Previous psychoanalytic research has mainly dealt with the psychological integration of the new organ and the conscious and unconscious relationship of the recipient to the transplanted organ and the donor. Some works have also explored organ transplantation from a Lacanian perspective,
Lutz Goetzmann   +8 more
wiley   +1 more source

Dysregulation of the endosomal sorting complex III is linked to neurodegeneration in progressive multiple sclerosis

open access: yesBrain Pathology, EarlyView.
This study shows that components of the ESCRT‐III membrane repair machinery, VPS4B and CHMP2A, are dysregulated in progressive MS and are associated with higher neurodegeneration and inflammation. This might lead to improper function of the complex to inhibit the final stages of necroptosis activation and thus impede neuronal cell death.
Carmen Picon   +5 more
wiley   +1 more source

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