Results 81 to 90 of about 182,666 (399)
Frontiers in Endocrinology, 2021 Patients with diabetes are over-represented among the total cases reported with “idiopathic” pulmonary fibrosis (IPF). This raises the question, whether this is an association only or whether diabetes itself can cause pulmonary fibrosis.
Stefan Kopf +15 more
doaj +1 more source
Tackling MARCKS-PIP3 circuit attenuates fibroblast activation and fibrosis progression. [PDF]
, 2019 Targeting activated fibroblasts, including myofibroblast differentiation, has emerged as a key therapeutic strategy in patients with idiopathic pulmonary fibrosis (IPF).
Chen, Ching-Hsien +7 more
core +2 more sources
The treatment of idiopathic pulmonary fibrosis [PDF]
F1000Prime Reports, 2014 Idiopathic pulmonary fibrosis (IPF) is a progressive and invariably fatal disease with a median survival of less than three years from diagnosis. The last decade has seen an exponential increase in clinical trial activity in IPF and this in turn has led to important developments in the treatment of this terrible disease. Previous therapeutic approaches
Woodcock, HV, Maher, TM
openaire +5 more sources
Nature Communications, 2023 The activation and accumulation of lung fibroblasts resulting in aberrant deposition of extracellular matrix components, is a pathogenic hallmark of Idiopathic Pulmonary Fibrosis, a lethal and incurable disease.
Ilianna Barbayianni +14 more
doaj +1 more source
BDNF/TrkB axis activation promotes epithelial-mesenchymal transition in idiopathic pulmonary fibrosis [PDF]
, 2017 Background: Neurotrophins (NT) belongs to a family of growth factors which promotes neurons survival and differentiation. Increasing evidence show that NT and their receptor are expressed in lung tissues suggesting a possible role in lung health and ...
Bruno, Pierdonato +8 more
core +1 more source
Idiopathic Pulmonary Fibrosis and Telomeres
Journal of Clinical Medicine, 2022 Idiopathic pulmonary fibrosis is an interstitial lung disease of unknown etiology with a highly compromised prognosis and a significant mortality rate within a few years of diagnosis. Despite being idiopathic, it has been shown that telomeric shortening could play an important role in its etiopathogenesis.
Alba Mulet, Jaime Signes-Costa
openaire +3 more sources
Journal of Applied Clinical Medical Physics, EarlyView.Abstract This study aimed to compare the treatment plans of x‐ray SBRT and scanning carbon ion radiation therapy (CIRT) for localized lung tumors, and to evaluate the dose dependence of tumor size tumor‐to‐heart distance. For phantom verification, we used a chest phantom with a spherical simulated tumor.
Yuya Miyasaka +8 more
wiley +1 more source
Acute Exacerbation of Idiopathic Pulmonary Fibrosis
Medicina, 2019 Idiopathic pulmonary fibrosis (IPF) is the most common form of idiopathic interstitial pneumonia. Idiopathic pulmonary fibrosis is often seen in elderly men who smoke.
Tomoo Kishaba
doaj +1 more source
Idiopathic pulmonary fibrosis: a clinical case of long-term follow-up
Consilium Medicum, 2022 Idiopathic pulmonary fibrosis is a specific form of chronic progressive fibrotic interstitial pneumonia of unknown etiology. Over the past decade, significant progress has been made in developing and utilizing a diagnostic algorithm for patients with ...
Galina L. Ignatova +3 more
doaj +1 more source
Margin-Aware Intra-Class Novelty Identification for Medical Images [PDF]
Journal of Medical Imaging 2022, 2021 Traditional anomaly detection methods focus on detecting inter-class variations while medical image novelty identification is inherently an intra-class detection problem. For example, a machine learning model trained with normal chest X-ray and common lung abnormalities, is expected to discover and flag idiopathic pulmonary fibrosis which a rare lung ...
arxiv