Results 81 to 90 of about 150,446 (235)
The Idiopathic Pulmonary Fibrosis Cell Atlas.
American Journal of Physiology - Lung cellular and Molecular Physiology, 2020 16 Idiopathic Pulmonary fibrosis (IPF) is an incurable disease in which the normal lung anatomy is replaced 17 by a process of active remodeling, and deposition of extracellular matrix (ECM) accompanied by a shift 18 in lung cellular communities. Several
N. Neumark +3 more
semanticscholar +1 more source
Idiopathic pulmonary fibrosis: An update
Annals of Medicine, 2015 Idiopathic pulmonary fibrosis (IPF) is the most common and lethal form of idiopathic interstitial pneumonia. The disease, which occurs primarily in middle-aged and older adults, is thought to arise following an aberrant reparative response to alveolar epithelial cell injury characterized by secretion of excessive amounts of extracellular matrix ...
Spagnolo P1 +6 more
openaire +4 more sources
Mode of action of nintedanib in the treatment of idiopathic pulmonary fibrosis
European Respiratory Journal, 2015 Idiopathic pulmonary fibrosis (IPF) is a progressive and ultimately fatal disease characterised by fibrosis of the lung parenchyma and loss of lung function. Although the pathogenic pathways involved in IPF have not been fully elucidated, IPF is believed
L. Wollin +6 more
semanticscholar +1 more source
Cells, 2019 Idiopathic pulmonary fibrosis (IPF) has been linked to chronic lung inflammation. Drosha ribonuclease III (DROSHA), a class 2 ribonuclease III enzyme, plays a key role in microRNA (miRNA) biogenesis.
Soo Jung Cho +6 more
doaj +1 more source
Idiopathic Pulmonary Fibrosis and Lung Cancer: Mechanisms and Molecular Targets
International Journal of Molecular Sciences, 2019 Idiopathic pulmonary fibrosis (IPF) is the most common idiopathic interstitial pulmonary disease with a median survival of 2–4 years after diagnosis.
Beatriz Ballester, J. Milara, J. Cortijo
semanticscholar +1 more source
Interleukin-11 is a therapeutic target in idiopathic pulmonary fibrosis
Science Translational Medicine, 2019 Interleukin-11 is important for lung fibroblast activation in idiopathic pulmonary fibrosis, and its signaling represents a therapeutic target. Targeting IL-11 in lung fibrosis In idiopathic pulmonary fibrosis (IPF), chronic activation of invasive ...
B. Ng +21 more
semanticscholar +1 more source
Consensus document for the diagnosis and treatment of idiopathic pulmonary fibrosis
Revista Portuguesa de Pneumologia (English Edition), 2016 Idiopathic pulmonary fibrosis is a rare interstitial lung disease included in the Idiopathic Interstitial Pneumonias group. Although several potential risk factors have been described, it is a progressive fibrosing disease of unknown cause affecting ...
C. Robalo Cordeiro +12 more
doaj
Canadian Respiratory Journal, 2004 The case of a patient that developed pulmonary fibrosis two months after initiation of danazol for treatment of idiopathic thrombocytopenic purpura is described.
Smita Pakhale +3 more
doaj +1 more source
A Staphylococcus pro-apoptotic peptide induces acute exacerbation of pulmonary fibrosis
Nature Communications, 2020 Idiopathic pulmonary fibrosis is associated with increased abundance of Staphylococcus and Streptococcus in the lungs. Here, the authors identify a Staphylococcus nepalensis-derived peptide, named corisin, to induce apoptosis of lung epithelial cells and
Corina N. D’Alessandro-Gabazza +34 more
doaj +1 more source
The therapy of idiopathic pulmonary fibrosis: what is next?
European Respiratory Review, 2019 Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibrosing interstitial lung disease, characterised by progressive scarring of the lung and associated with a high burden of disease and early death.
V. Somogyi +5 more
semanticscholar +1 more source