Results 91 to 100 of about 3,357,239 (197)

Monogenic causes of familial short stature

Frontiers in Endocrinology
Genetic factors play a crucial role in determining human height. Short stature commonly affects multiple family members and therefore, familial short stature (FSS) represents a significant proportion of growth disorders. Traditionally, FSS was considered
Lukas Plachy, Petra Dusatkova, Shenali Anne Amaratunga, Vit Neuman, Zdenek Sumnik, Jan Lebl, Stepanka Pruhova   +6 more
doaj   +1 more source

Cytoplasmic and nuclear STAT3 in GH-stimulated fibroblasts of children with idiopathic short stature [PDF]

, 2010
Background: STAT5, which plays an important role in GH signal transduction, has been studied extensively in children with growth retardation, but there is scarce information regarding STAT3.
Cassorla Goluboff, Fernando, Teresa Salazar, Ariel Fuentes, Paula Ocaranza, Rossana Román, Martínez Pinto, Jonathan, Fuentes, Ariel, Salazar, Teresa, Fernando Cassorla, Jonathan Martínez Pinto, Ocaranza, Paula, Román, Rossana   +11 more
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Metabolic Characteristics and Discriminative Diagnosis of Growth Hormone Deficiency and Idiopathic Short Stature in Preadolescents and Adolescents

Molecules
Growth hormone deficiency (GHD) and idiopathic short stature (ISS) are the most common types of short stature (SS), but little is known about their pathogenesis, and even less is known about the study of adolescent SS.
Yajie Chang, Jing Chen, Hongwei Zhu, Rong Huang, Jinxia Wu, Yanyan Lin, Quanquan Li, Guiping Shen, Jianghua Feng   +8 more
doaj   +1 more source

Diagnosis and management of growth disorders in Gulf Cooperation Council (GCC) countries: Current procedures and key recommendations for best practice

International Journal of Pediatrics & Adolescent Medicine, 2016
Diagnosis and management of growth disorders comprises an important area of pediatric practice. Current procedures in the different stages of the identification, referral, investigation, and treatment of growth disorders in the Gulf Cooperation Council ...
Abdullah S. Al Herbish, Angham Almutair, Bassam Bin Abbas, Afaf Alsagheir, Mohammed Alqahtani, Walid Kaplan, Asma Deeb, Ahmed El-Awwa, Mona Al Khawari, Ekaterina Koledova, Martin O. Savagej   +10 more
doaj   +1 more source

Idiopathic short stature and growth hormone sensitivity in prepubertal children

, 2019
Objective: We compared growth hormone sensitivity to an insulin-like growth factor I (IGF-I) generation test in children with idiopathic short stature (ISS) and of normal stature (NS) across the birthweight range.Methods: Forty-six prepubertal children (~
Harriet L. Miles, Wayne S. Cutfield, Miles, Harriet L.,, Valentina Chiavaroli, Paul L. Hofman, Hofman, Paul L.,, Cutfield, Wayne S.,, Derraik, Jose G. B.,, Chiavaroli, Valentina,, José G. B. Derraik   +9 more
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Criteria for Treating Children with Idiopathic Short Stature: Laboratory (Biochemical)

, 2011
Idiopathic short stature (ISS) is a diagnosis of exclusion. No specific laboratory test can identify it. Rather, a series of tests that examine a person’s genetic, nutritional and hormonal makeup are used to exclude specific diagnoses.
Steven D. Chernausek
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Growth indices and vitamin D content in children with idiopathic short stature depending on the variants of the Taql polymorphism genotype of the VDR gene

Mìžnarodnij Endokrinologìčnij Žurnal
Background. The vitamin D receptor (VDR) gene is a key regulator of biological processes, including tissue and cell growth and differentiation, bone metabolism, and modulation of immune responses.
M.O. Ryznychuk, O.V. Bolshova
doaj   +1 more source

Controversies in the definition and treatment of idiopathic short stature ISS.

, 2009
The term idiopathic short stature (ISS) refers to short children with no identifiable disorder of the growth hormone (GH)/insulin like growth factor (IGF) axis and no other endocrine, genetic or organ system disorder.
Cianfarani S, CIANFARANI, STEFANO, Peschiaroli E, Violi E, Pedicelli S   +4 more
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Growth (including short stature and tall stature)

, 2011
Introduction 2Measurement techniques 6Physiology 10Growth disorders 12Causes of short stature 14Investigation of short stature 22Therapy for short stature 24Introduction to tall stature 28Constitutional tall stature 30Exogenous obesity 31Syndromic tall ...
Gary Butler, Jeremy Kirk
core   +1 more source

SHOX gene analysis with Fluoresant in situ Hybridization and sequence methods in idiopathic short stature patients

, 2013
İdiyopatik boy kısalığı olan hastalarda Floresan in situ Hibridizasyon ve dizi analizi yöntemleri ile SHOX geninin araştırılması. Boy uzamasını çevresel ve genetik faktörler birlikte etkilemektedir ve boy kısalığı bir bireyin boy uzunluğunun kendi yaş ...
Bakır, Abdullatif
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