Results 71 to 80 of about 3,357,239 (197)

Immunoglobulin a Deficiency in Coeliac Disease: A Scoping Review

United European Gastroenterology Journal, Volume 14, Issue 8, October 2026.
ABSTRACT Coeliac disease (CeD) and immunoglobulin A deficiency (IgAD) frequently co‐occur and share a genetic background within the HLA‐DQ2 region. Although this has been known for decades, the underlying mechanisms linking the two conditions remain unclear.
Kristine Bech, Cæcilie Crawley, Rok Seon Choung, Joseph A. Murray, Steffen Husby   +4 more
wiley   +1 more source

Prevalence of celiac disease in patients with short stature: A systematic review and meta‐analysis

, 2021
Background and AimShort stature is a common extraintestinal manifestation of celiac disease (CeD). We conducted a systematic review and meta‐analysis to assess the global prevalence of CeD in patients presenting with short stature.MethodsWe searched ...
Ahuja, Vineet, Makharia, Govind K, Tor Strand, Farooqui, Naba, Prashant Singh, Singh, Prashant, Govind K Makharia, Singh, Achintya D, Strand, Tor, Vineet Ahuja, Naba Farooqui, Achintya D Singh   +11 more
core   +1 more source

Jacobs Syndrome Presenting With Delayed Puberty and Central Hypogonadism: A Rare Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT In some rare instances, patients with 47,XYY syndrome can be short in height, accompanied by hypogonadism without the characteristic tall stature. In cases where there is delayed puberty and unusual growth pattern, a complete endocrine work‐up, including GnRH and hCG stimulation tests, along with chromosome studies, is vital.
Muhammad Hassaan Javaid, Ayesha Ahmad, Amna Ahmad, Muhammad Ajmal Khamosh, Muhammad Hanzla   +4 more
wiley   +1 more source

Advances in FGF/FGFR Signaling: Implications for Disease and Therapy

MedComm, Volume 7, Issue 9, September 2026.
The FGF/FGFR signaling is indispensable for the maintenance of physiological homeostasis and governs multiple biological processes, including embryonic development, bone metabolism, angiogenesis, and neurogenesis, whereas aberrant hyperactivation of this pathway drives the progression of malignancies and autoimmune disorders, including inflammatory ...
Miaoyu Song, Xi Liu, Yang Xiao, Yongsheng Li, Huakan Zhao   +4 more
wiley   +1 more source

Precision Dosing for Pediatric Growth Hormone Deficiency With Daily and Weekly Growth Hormone

MedComm, Volume 7, Issue 9, September 2026.
• This study supports precision dosing and switching between daily rhGH and weekly PEG‐rhGH in pediatric GHD. • Missed doses reduce treatment benefit more with daily rhGH than with weekly PEG‐rhGH. • The findings provide guidance for growth hormone dosing and monitoring in pediatric GHD.
Wei Wu, Chun‐Xiu Gong, Jie Mei, Ling Hou, Yan Liang, Yan‐qin Ying, Feng Ye, Ge‐Hang Ju, Hui‐Xiang Tian, Nan Yang, Yun Qin, Dongsheng Ouyang, Xiaoping Luo   +12 more
wiley   +1 more source

Impact of growth hormone therapy on adult height of children with idiopathic short stature: systematic review

, 2011
To systematically determine the impact of growth hormone therapy on adult height of children with idiopathic short ...
Deodati, A, Cianfarani, S, S. Cianfarani, A. Deodati   +3 more
core   +1 more source

Analysis of SHOX gene regulatory and coding region variants in pediatric patients with idiopathic short stature [PDF]

, 2020
Nizka rast je pogosto razvojno stanje v otroštvu. Opredeljena je kot telesna višina, ki je manjša od dveh standardnih odklonov (-2 SD) povprečne višine za spol, starost in populacijo.
Stritar, Jera
core  

Analysis of Genetic Factors in a Family With Short Stature

Molecular Genetics &Genomic Medicine, Volume 14, Issue 9, September 2026.
We identified pathogenic variants of two different genes, COL1A2 and GH1, in a family with short stature through trio‐WES, thereby providing a clear genetic diagnosis for this family. ABSTRACT Background To elucidate the genetic underpinnings of short stature in a familial cohort of five individuals.
Siqing Zhang, Tian Zuo, Youping Deng, Dongchi Zhao, Lihong Liao   +4 more
wiley   +1 more source

Growth Hormone Treatment Response and Machine Learning‐Based Prediction in Idiopathic GHD and ISS: Analysis of the Korean LG Growth Study

Clinical Endocrinology, Volume 105, Issue 3, Page 322-330, September 2026.
ABSTRACT Objective Individual responses to recombinant human growth hormone (rhGH) therapy vary widely among children with idiopathic growth hormone deficiency (iGHD) and idiopathic short stature (ISS), making accurate prediction of treatment outcomes clinically important.
Jisun Park, Eun Young Joo, Su Jin Kim, Myung Ji Yoo, Ji Eun Lee   +4 more
wiley   +1 more source

Management of children with idiopathic short stature [PDF]

European Journal of Endocrinology, 2006
The Food and Drug Administration (FDA) approved the use of biosynthetic GH for the treatment of children with idiopathic short stature (ISS) in the US in 2003. Primarily, the decision was based on two studies: a randomized placebo-controlled study and a dose–response study, both demonstrating an increase in adult height over the predicted height at ...
openaire   +1 more source