Results 51 to 60 of about 3,357,239 (197)

Classification, diagnosis, and treatment of idiopathic short stature

Problems of Endocrinology, 2009
Idiopathic short stature is the low stature in which all possible causes are excluded. The diagnosis and treatment of idiopathic short stature are the subject of constant controversy and discussion. With the expansion of indications for growth hormone therapy for conditions unaccompanied by growth hormone deficiency, there has been recently a challenge
A N, Shandin, V A, Peterkova
openaire   +2 more sources

Debate: idiopathic short stature should be treated with growth hormone

, 2013
In this paper we outline the case for and against the treatment of idiopathic short stature with growth hormone. Drs Ambler and Fairchild argue that many of those with ‘idiopathic’ short stature are not ‘short, normal children’ and will ultimately ...
Fairchild, J., Wilkinson, D., Ambler, G.
core   +1 more source

Orthodontic treatment for a mandibular prognathic girl of short stature under growth hormone therapy

Journal of the Formosan Medical Association, 2013
This report presents a case of a 12-year-old girl with maxillary deficiency, mandibular prognathism, and facial asymmetry, undergoing growth hormone (GH) therapy due to idiopathic short stature.
Chin-Yun Pan, Ting-Hung Lan, Szu-Ting Chou, Yu-Chuan Tseng, Jenny Zwei-Chieng Chang, Hong-Po Chang   +5 more
doaj   +1 more source

Growth hormone therapy response in children with short stature

Egyptian Pediatric Association Gazette, 2023
Background Short stature is one of the main causes of children referral to pediatric endocrinologists. Common etiologies include idiopathic growth hormone deficiency (IGHD), small for gestational age (SGA), and idiopathic short stature (ISS).
Amira Ahmed Gad, Radwa Shamma, Mohamed A. Elmonem, Nora E. Badawi, Lubna Fawaz, Mona Mamdouh Hassan   +5 more
doaj   +1 more source

Diagnostic Yield of Brain MRI in Pediatric Short Stature: Hypothalamic–Pituitary Lesions and Incidental Findings in Real‐World Practice

Clinical Endocrinology, EarlyView.
ABSTRACT Background Brain MRI is widely performed in children with short stature or suspected growth hormone deficiency(GHD) to exclude hypothalamic–pituitary (HP) pathology, yet its diagnostic yield in routine practice is uncertain. We aimed to evaluate the prevalence, clinical significance, and distribution of HP and extrahypothalamic abnormalities ...
Mustafa Zubeidat, Tamer Sobeh, Shai Shrot   +2 more
wiley   +1 more source

Abnormal GH receptor signaling in children with idiopathic short stature.

, 2001
Peripheral GH insensitivity may underlie idiopathic short stature in children. As the clinical and biochemical hallmarks of partial GH insensitivity have not yet been clearly elucidated, the identification of such patients is still difficult.
Fimiani G., Balestrieri B., Ursini M. V., Matrecano E., Officioso A., SALERNO, MARIACAROLINA, PIGNATA, CLAUDIO, Rosenfeld R. G., Di Maio S.   +8 more
core   +1 more source

A Novel Heterozygous ACAN Variant in a Short Patient Born Small for Gestational Age with Recurrent Patellar Dislocation: A Case Report

JCRPE, 2022
ACAN variants can manifest as various clinical features, including short stature, advanced bone age (BA), and skeletal defects. Here, we report rare clinical manifestations of ACAN defects in a 9 year, 5 month-old girl born small for gestational age (SGA)
Su Ji Kim, Jong Seo Yoon, Il Tae Hwang
doaj   +1 more source

GSK3α‐mediated regulation of the RNA demethylase fat mass and obesity‐associated protein (FTO) during murine spermatogenesis

The FEBS Journal, EarlyView.
FTO regulates mRNA stability and translational efficiency through its m6A‐demethylation activity. GSK3 functions as an upstream regulator of FTO, leading to its inhibition via phosphorylation. In male germ cells, FTO activity is kept in check by GSK3α.
Neha Choudhari, Budheswar Dehury, Rounak Roy, Radhakrishnan Periyasamy, Indrashis Bhattacharya, Mahesh Sahare, Srinivasan Vijayraghavan, Souvik Dey   +7 more
wiley   +1 more source

Idiopathic short stature. Is it a disease? [PDF]

, 2014
This bachelor thesis is focused on idiopathic short stature. Idiopathic short stature can be found a tup to 80% of children, who suffer from growth disorders. I tis a short stature without definite reasons.
Šneberková, Klára
core  

Healthy short stature [PDF]

Archives of Endocrinology and Metabolism
Idiopathicshort stature (ISS) has been used for more than five decades to label children whose height is below -2 SDS without an identified underlying cause.
Alexander A. L. Jorge, Paulo F. Collett-Solberg, Margaret C. S. Boguszewski   +2 more
doaj   +2 more sources