Results 31 to 40 of about 3,357,239 (197)

Short stature and SHOX (Short stature homeobox) variants—efficacy of screening using various strategies [PDF]

PeerJ, 2020
Background SHOX mutations have previously been described as causes of Léri-Weill dyschondrosteosis (LWD), Langer mesomelic dysplasia (LMD), and idiopathic short stature. The loss of X chromosome—Turner syndrome or mosaic 45,X/46,XX or 46,XY—also leads to
Pavlina Capkova, Zuzana Capkova, Peter Rohon, Katerina Adamová, Jirina Zapletalova   +4 more
doaj   +2 more sources

Quality of Life of Short-Statured Children Born Small for Gestational Age or Idiopathic Growth Hormone Deficiency Within 1 Year of Growth Hormone Treatment

Frontiers in Pediatrics, 2019
Aside from clinical endpoints like height gain, health-related quality of life has also become an important outcome indicator in the medical field. However, the data on short stature and health-related quality of life is inconsistent.
Julia Quitmann, Janika Bloemeke, Neuza Silva, Neuza Silva, Monika Bullinger, Stefanie Witt, Ilker Akkurt, Desiree Dunstheimer, Christian Vogel, Volker Böttcher, Ursula Kuhnle Krahl, Markus Bettendorf, Eckhard Schönau, Susanne Fricke-Otto, Alexandra Keller, Klaus Mohnike, Helmuth-Günther Dörr   +16 more
doaj   +1 more source

Molecular mechanisms underlying growth hormone insensitivity and idiopathic short stature [PDF]

, 2009
PhDShort stature can be due to several causes, including genetically transmitted insensitivity to the action of growth hormone (GHI). In approximately 80% of referred patients, no aetiology can be identified and they are classified as having idiopathic
David, Alessia
core   +4 more sources

Clonidine-stimulated growth hormone concentrations (cut-off values) measured by immunochemiluminescent assay (ICMA) in children and adolescents with short stature

Clinics, 2016
OBJECTIVES: To establish cut-off values for growth hormone concentrations using clonidine as a secretagogue and an immunochemiluminescent assay as the method of measurement and to analyze the response time as well as the influence of gender, nutritional ...
Maria de Fátima Borges, Flávia Carolina Cândida Teixeira, Aline Karin Feltrin, Karina Alvarenga Ribeiro, Gabriel Antonio Nogueira Nascentes, Elisabete Aparecida Mantovani Rodrigues Resende, Beatriz Pires Ferreira, Adriana Paula Silva, Heloísa Marcelina Cunha Palhares   +8 more
doaj   +1 more source

Assessment and referral of patients with short stature by primary care physicians in the Arabian gulf region: Current perspectives from a regional survey

Frontiers in Pediatrics, 2022
Children with short stature are frequently referred late to pediatric endocrinologists in the Arabian Gulf region. This is likely a contributing factor to late initiation of treatment despite current evidence suggesting that children with short stature ...
W. Kaplan, E. Al Amiri, N. Attia, I. Al Basiri, I. Romany, E. Al Shehri, E. Al Shehri, A. Al Twaim, S. Al Yaarubi, A. Deeb, A. Deeb   +10 more
doaj   +1 more source

SHOX Gene Screening in Familial Short-stature Females [PDF]

Journal of Medical Academics
Introduction: As idiopathic short stature (ISS) has been linked to mutations in the SHOX gene, research into SHOX gene mutations in idiopathic familial short stature (FSS) is crucial. Early intervention planning necessitates the timely evaluation of FSS.
Karishma Sharma, Prashant Kumar Verma, Shashi Ranjan Mani Yadav, Brijendra Singh, Manisha Naithani   +4 more
doaj   +1 more source

Idiopathic Short Stature - A Case Report

Bangladesh Journal of Child Health, 2023
Short stature in childhood is the most common reason for referral to pediatric endocrinologists. Idiopathic short stature is defined as ³2 SD below the corresponding mean height for a given age, sex, and population in a child with a normal birth size and normal body proportions and without evidence of any systemic, endocrine, nutritional, or ...
Suraiya Begum, Dhiraj Chandra Biswas
openaire   +1 more source

Analysis of A Case of Growth Retardation of Infants Caused By Maternal Medication During Lactation [PDF]

BIO Web of Conferences
Short stature in childhood and even adulthood mostly originates from infancy and young children. It has been reported that 30.7% of children start to experience short stature before 6 months of age, 32.3% of children start to experience short stature ...
Zhang Junhua
doaj   +1 more source

Comparative efficacy of aromatase inhibitors and gonadotropin-releasing hormone analogue in increasing final height of idiopathic short stature boys: a network meta-analysis

Frontiers in Endocrinology, 2023
ObjectiveTo investigate the efficacy of monotherapy with AIs or GnRHa in improving the height of boys with idiopathic short stature (ISS).MethodWe performed a systematic search in Pubmed, The Cochrane Library, Chinese National Knowledge Infrastructure ...
Siqi Wang, Zhixin Wu, Yang Chen, Kuanhong Luo, Zhenhai Cui, Jiaoyue Zhang, Juan Zheng, Kangli Xiao, Huiqing Li   +8 more
doaj   +1 more source

Health economic evaluation on idiopathic short stature: a protocol for systematic review

, 2021
Idiopathic short stature causes a high economic burden worldwide. There are no articles that analyze health-related economic evaluations for available interventions for ...
Chan-Young Kwon, Boram Lee
core   +1 more source