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Idiopathic short stature: Definition, epidemiology, and diagnostic evaluation

open access: yesGrowth Hormone and IGF Research, 2008
Idiopathic short stature is a condition in which the height of the individual is more than 2 SD below the corresponding mean height for a given age, sex and population, in whom no identifiable disorder is present.
Martin O. Savage   +2 more
exaly   +2 more sources
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Idiopathic Short Stature

Endocrinology and Metabolism Clinics of North America, 2005
The diagnostic term, idiopathic short stature, has emerged over the past 30 years and refers to children with short stature of unknown etiology. Controversy exists regarding the scope of the diagnosis and options for its treatment. This article reviews origins of the diagnosis idiopathic short stature and current diagnostic criteria, scientific ...
Rose A, Gubitosi-Klug, Leona, Cuttler
openaire   +2 more sources

The molecular basis of idiopathic short stature

Growth Hormone and IGF Research, 2005
Forty years ago, when growth hormone (GH) first became available for use, the molecular basis for growth hormone deficiency (GHD) was entirely unknown. Despite continued difficulties with the biochemical diagnosis of GHD, we now accept the existence of underlying genetic abnormalities as the basis for disorders involving GH secretion.

exaly   +3 more sources

Idiopathic Short Stature in Children

Pediatric Annals, 2004
Despite a lack of clear etiology or diagnostic tests, treatment for this condition should not be ...
Bradley S, Miller, Donald, Zimmerman
openaire   +2 more sources

Psychological Adaptation in Children with Idiopathic Short Stature Treated with Growth Hormone or Placebo [PDF]

open access: yesJournal of Clinical Endocrinology and Metabolism, 2004
The influence of short stature on psychological adaptation in childhood and adolescence is controversial. GH is currently used to treat children with idiopathic short stature (ISS, also known as non-GH-deficient short stature).
David E. Sandberg   +2 more
exaly   +2 more sources

Idiopathic Short Stature

JAMA, 2014
Approximately 2% of children are defined as having short stature. Deciding when to pursue recombinant human growth hormone therapy to increase adult height is controversial.To review the management of children with idiopathic short stature, including diagnostic evaluation and therapeutic options.Systematic literature search of PubMed, Embase, and the ...
openaire   +2 more sources

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