Results 11 to 20 of about 13,654 (259)

Quality of Life of Short-Statured Children Born Small for Gestational Age or Idiopathic Growth Hormone Deficiency Within 1 Year of Growth Hormone Treatment [PDF]

open access: yesFrontiers in Pediatrics, 2019
Aside from clinical endpoints like height gain, health-related quality of life has also become an important outcome indicator in the medical field. However, the data on short stature and health-related quality of life is inconsistent.
Julia Quitmann   +16 more
doaj   +4 more sources

Children With Short Stature Display Reduced ACE2 Expression in Peripheral Blood Mononuclear Cells [PDF]

open access: yesFrontiers in Endocrinology, 2022
BackgroundThe cause of short stature remains often unknown. The renin-angiotensin system contributes to growth regulation. Several groups reported that angiotensin-converting enzyme 2 (ACE2)-knockout mice weighed less than controls.
Federica Tonon   +10 more
doaj   +3 more sources

Idiopathic Short Stature: Conundrums of Definition and Treatment [PDF]

open access: yesInternational Journal of Pediatric Endocrinology, 2009
Children with idiopathic short stature (ISS) are statistically defined by height SDS < -2 for their bone age and should be distinguished from children with familial short stature for whom height SDS corresponds to mean parental SDS and from the most common explanation for short stature referred to pediatric endocrinologists, constitutional delay in ...
Rosenbloom, Arlan L.
openaire   +7 more sources

Managing idiopathic short stature: role of somatropin (rDNA origin) for injection [PDF]

open access: yesBiologics: Targets & Therapy, 2010
J Paul Frindik1, Stephen F Kemp11University of Arkansas for Medical Sciences and Arkansas Children&rsquo;s Hospital, AR, USAAbstract: Idiopathic short stature (ISS) is a term that describes short stature in children who do not have growth hormone (GH)
J Paul Frindik, Stephen F Kemp
doaj   +3 more sources

Case analysis and literature review of 3 children with short stature with ACAN gene mutation [PDF]

open access: yesZhenduanxue lilun yu shijian, 2023
Objective: To analyze the clinical features and genetic changes of 3 children in short stature with ACAN gene mutation. Methods: The clinical data, laboratory examinations, and genetic testing results of 3 children with ACAN gene mutations diagnosed with
LI Yanxiao, LU Wenli, WANG Xinqiong, CHEN Ye, XIAO Yuan, DONG Zhiya, MA Xiaoyu
doaj   +1 more source

Prevalence and Aetiological Profile of Short Stature in School Children between 6-11 Years of Age- A Community Based Prospective Observational Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2023
Introduction: Growth is a complex process and influenced by genetic back ground, different functions of endocrine system, nutrition, effect of any chronic disease and the level of individual physical activity.
Jasmine Kandagal   +3 more
doaj   +1 more source

Involvement of the vitamin D receptor gene in the development of idiopathic short stature

open access: yesMìžnarodnij Endokrinologìčnij Žurnal, 2023
Background. The vitamin D receptor (VDR) gene is loca­lized in the chromosome 12 (region 12q13). Its polymorphic variants BsmI and FokI are the most promising in clinical and diagnostic terms.
O.V. Bolshova   +2 more
doaj   +1 more source

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