Results 201 to 210 of about 52,117 (235)
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Journal of Pediatric Endocrinology and Metabolism, 2001
Abstract Idiopathic short stature (ISS) is a term used to describe the status of children with short stature that cannot be attributed to a specific cause. Many children diagnosed as having ISS have partial GH insensitivity, which can result from disturbances at various points of the GH-IGF-I axis.
PASQUINO AM +10 more
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Abstract Idiopathic short stature (ISS) is a term used to describe the status of children with short stature that cannot be attributed to a specific cause. Many children diagnosed as having ISS have partial GH insensitivity, which can result from disturbances at various points of the GH-IGF-I axis.
PASQUINO AM +10 more
openaire +4 more sources
Idiopathic short stature and scoliosis in children treated with growth hormone.
The Bone & Joint Journal, 2023The prevalence of scoliosis is not known in patients with idiopathic short stature, and the impact of treatment with recombinant human growth hormone on those with scoliosis remains controversial.
Haofeng Hong +7 more
semanticscholar +1 more source
Endocrinology and Metabolism Clinics of North America, 2005
The diagnostic term, idiopathic short stature, has emerged over the past 30 years and refers to children with short stature of unknown etiology. Controversy exists regarding the scope of the diagnosis and options for its treatment. This article reviews origins of the diagnosis idiopathic short stature and current diagnostic criteria, scientific ...
Rose A, Gubitosi-Klug, Leona, Cuttler
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The diagnostic term, idiopathic short stature, has emerged over the past 30 years and refers to children with short stature of unknown etiology. Controversy exists regarding the scope of the diagnosis and options for its treatment. This article reviews origins of the diagnosis idiopathic short stature and current diagnostic criteria, scientific ...
Rose A, Gubitosi-Klug, Leona, Cuttler
openaire +2 more sources
Short stature homeoboxcontaining gene and idiopathic short stature
Expert Review of Endocrinology & Metabolism, 2009The term idiopathic short stature (ISS) refers to patients who are short due to various unknown reasons. Although it is clear that multiple factors contribute to final height, genetic factors play a crucial role. Mutations of a human homeobox gene, short stature homeobox-containing (SHOX) gene, have been shown to be associated with the short stature ...
IUGHETTI, Lorenzo +6 more
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Idiopathic Short Stature in Children
Pediatric Annals, 2004Despite a lack of clear etiology or diagnostic tests, treatment for this condition should not be ...
Bradley S, Miller, Donald, Zimmerman
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JAMA, 2014
Approximately 2% of children are defined as having short stature. Deciding when to pursue recombinant human growth hormone therapy to increase adult height is controversial.To review the management of children with idiopathic short stature, including diagnostic evaluation and therapeutic options.Systematic literature search of PubMed, Embase, and the ...
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Approximately 2% of children are defined as having short stature. Deciding when to pursue recombinant human growth hormone therapy to increase adult height is controversial.To review the management of children with idiopathic short stature, including diagnostic evaluation and therapeutic options.Systematic literature search of PubMed, Embase, and the ...
openaire +2 more sources
2011
Idiopathic short stature is a condition in which the height of the individual is more than 2 SD below the corresponding mean height for a given age, sex, and population, and in whom no identifiable disorder is present. It can be subcategorized into familial and non-familial ISS, according to information on delay of puberty and bone age.
Meinolf Noeker +2 more
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Idiopathic short stature is a condition in which the height of the individual is more than 2 SD below the corresponding mean height for a given age, sex, and population, and in whom no identifiable disorder is present. It can be subcategorized into familial and non-familial ISS, according to information on delay of puberty and bone age.
Meinolf Noeker +2 more
openaire +1 more source
Spontaneous Adult Height in Idiopathic Short Stature
Hormone Research, 1995Two hundred and thirty-six patients with idiopathic short stature (ISS) (184 m, 52 f) who presented at a mean age of 12.2 (range 2.8-17.5) years, a mean height of -2.16 standard deviation score (SDS), a mean target height (THT) of -0.27 SDS (m = f), were reinvestigated at a mean age of 20.5 (range 18-24) years. 182(142 m, 37 f) (67%) had reached normal
M B, Ranke +4 more
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Genetic studies in idiopathic short stature
Current Opinion in Pediatrics, 2000Idiopathic short stature (ISS) refers to a heterogeneous group of children with marked growth failure of unknown cause, and encompasses familial short stature and constitutional delay of growth. It has been postulated that specific genetic mutations may explain certain cases of growth failure.
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Psychological Functioning in Idiopathic Short Stature
Hormone Research in Paediatrics, 2011Living with idiopathic short stature (ISS) may entail significant risks to psychological functioning and quality of life. Apparent inconsistency among study findings can be resolved if methodological differences among study designs are taken into account (i.e., definition of particular endpoints, sample selection from clinic or population, source of ...
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