Results 211 to 220 of about 52,117 (235)

Effect of growth hormone treatment on children with idiopathic short stature (ISS), idiopathic growth hormone deficiency (IGHD), small for gestational age (SGA) and Turner syndrome (TS) in a tertiary care center

Acta bio-medica : Atenei Parmensis, 2020
Objectives: To assess the long-term effect of growth hormone (GH) therapy in a large cohort of short children with different etiologies. Patients and Methods: We evaluated retrospectively the anthropometric data of 252 short children [height SDS
Adnan Al Shaikh, Hadeer E Daftardar, AbdulRhamn Alghamdi, Majd Jamjoom, Saniah Awidah, Mohamed E. Ahmed, A. Soliman   +6 more
semanticscholar   +1 more source

The effect of treatment with recombinant human growth hormone (rhGH) on linear growth and adult height in children with idiopathic short stature (ISS): a systematic review and meta-analysis

Journal of Pediatric Endocrinology & Metabolism (JPEM), 2020
Objectives Idiopathic short stature (ISS) is a recognized, albeit a controversial indication for treatment with recombinant human growth hormone (rhGH).
G. Paltoglou, I. Dimitropoulos, G. Kourlaba, E. Charmandari   +3 more
semanticscholar   +1 more source

The molecular basis of idiopathic short stature

Growth Hormone & IGF Research, 2005
Forty years ago, when growth hormone (GH) first became available for use, the molecular basis for growth hormone deficiency (GHD) was entirely unknown. Despite continued difficulties with the biochemical diagnosis of GHD, we now accept the existence of underlying genetic abnormalities as the basis for disorders involving GH secretion.
openaire   +2 more sources

Growth Hormone Treatment of Idiopathic Short Stature

Hormone Research, 1996
Considerable controversy exists about the use of growth hormone (GH) treatment in short children without classical GH deficiency (idiopathic short stature or ISS). ISS is a multifactorial disorder with many potential causes rather than a single diagnostic entity, and it is in essence a diagnosis of exclusion.
openaire   +2 more sources

Idiopathic short stature: Management and growth hormone treatment

Growth Hormone & IGF Research, 2008
In the management of ISS auxological, biochemical, psychosocial and ethical elements have to be considered. In boys with constitutional delay of growth and puberty androgens are effective in increasing height and sexual characteristics, but adult height is unchanged.
J M, Wit, E O, Reiter, J L, Ross, P H, Saenger, M O, Savage, A D, Rogol, P, Cohen   +6 more
openaire   +2 more sources

Should We Treat Children with Idiopathic Short Stature?

Hormone Research in Paediatrics, 1999
The use of growth hormone (GH) to treat short children who are clearly GH-deficient is now well accepted. However, GH treatment of short children who have no currently recognizable abnormalities in their GH-insulin-like growth factor I axis remains controversial. Whether such children with so-called idiopathic short stature (ISS) should be treated with
C J, Kelnar, K, Albertsson-Wikland, R L, Hintz, M B, Ranke, R G, Rosenfeld   +4 more
openaire   +2 more sources

Idiopathic short stature: Definition, epidemiology, and diagnostic evaluation

Growth Hormone & IGF Research, 2008
Idiopathic short stature is a condition in which the height of the individual is more than 2 SD below the corresponding mean height for a given age, sex and population, in whom no identifiable disorder is present. It can be subcategorized into familial and non-familial ISS, and according to pubertal delay.
Wit, J. M., Clayton, P. E., Rogol, A. D., Savage, M. O., Saenger, P. H., Cohen, P.   +5 more
openaire   +2 more sources

Normal Variant and Idiopathic Short Stature

2018
This chapter reviews normal variant short stature, comprised of both familial short stature (FSS) and constitutional delay of growth and puberty (CDGP), as well as idiopathic short stature (ISS). FSS and CDGP are physiologic variants of short stature without an organic cause. Although ISS is not a “normal variant” of short stature, as with FSS and CDGP
Penny M. Feldman, Mary M. Lee
openaire   +1 more source

Hormonal Treatment of Idiopathic Short Stature

Hormone Research in Paediatrics, 2007
<i>Background and Objective:</i> The classification idiopathic short stature (ISS) represents a heterogeneous group of children who, as a group, are similar in height to patients with growth hormone (GH) deficiency, Turner syndrome, and short stature as a consequence of being born small for gestational age.
openaire   +1 more source

[Growth hormone and idiopathic short stature].

Annales d'endocrinologie, 2009
Idiopathic short stature is defined by height below 3rd percentile, in a child with normal birth height and weight, lack of dysmorphy, endocrine deficiency or systemic disease. Food and Drugs administration approved GH treatment in this indication in the United States, because it induces height gain, and sometimes may increase quality of life. There is
F, Castinetti, C, Fabre-Brue, T, Brue
openaire   +1 more source