Results 31 to 40 of about 52,117 (235)

Characteristics of intestinal microbiota in children with idiopathic short stature: a cross-sectional study

European Journal of Pediatrics, 2023
Idiopathic short stature (ISS) accounts for more than 70% of childhood short stature cases, with an undefined etiology and pathogenesis, leading to limited treatment.
Jing Miao, Panjian Lai, Kan Wang, Guoxing Fang, Xiaobing Li, Linqian Zhang, Mizu Jiang, Yunguang Bao   +7 more
semanticscholar   +1 more source

Levels and diagnostic values of serum visceral adipose tissue-derived serine protease inhibitor and secreted frizzle-related protein 5 in children with idiopathic short stature

Romanian Journal of Laboratory Medicine, 2023
Background: Idiopathic short stature (ISS) is a common type of short stature. We aimed to analyze the diagnostic values of serum visceral adipose tissue-derived serine protease inhibitor (Vaspin) and secreted frizzle-related protein 5 (SFRP5) for ISS ...
Che Ling, Chen Lei, Hou Binlan, Ouyang Fei, Zhou Huimei   +4 more
doaj   +1 more source

Long-acting PEGylated growth hormone in children with idiopathic short stature: time to reconsider our diagnostic and treatment policy?

European Journal of Endocrinology, 2023
Idiopathic short stature (ISS) is a diagnosis of exclusion, and therefore each child with short stature or slow growth referred to a paediatrician deserves a full medical history and physical examination, as well as radiological and laboratory screening ...
J. Wit, S. Joustra
semanticscholar   +1 more source

The Effect of The Height of a Second-Degree Relative on Children with Short Stature

Trends in Pediatrics, 2021
Objective: This study aimed to investigate the effect of the heights of second-degree relatives on adult height. Methods: This was a cross-sectional study.
Seda Yilmaz Semerci, Hasan Onal, Neval Topal, Rengin Siraneci   +3 more
doaj   +1 more source

Characteristics of Gut Microbiome and Its Metabolites, Short-Chain Fatty Acids, in Children With Idiopathic Short Stature

Frontiers in Endocrinology, 2022
Background The gut microbiome is important for host nutrition and metabolism. Whether the gut microbiome under normal diet regulate human height remains to be addressed.
Lin Li, Lifen Chen, Yuanyan Yang, Junqi Wang, Li Guo, Jingjing An, Xiaoyu Ma, Wenli Lu, Yuan Xiao, Xin-qiong Wang, Zhiya Dong   +10 more
semanticscholar   +1 more source

Response to growth hormone according to provocation test results in idiopathic short stature and idiopathic growth hormone deficiency

Annals of Pediatric Endocrinology & Metabolism, 2022
Purpose To investigate growth response in children with either idiopathic short stature (ISS) or growth hormone (GH) deficiency (GHD). Methods The data of prepubertal GHD or ISS children treated using recombinant human GH were obtained from the LG Growth
J. Yoon, C. Cheon, Jung Hyun Lee, M. Kwak, Hyun-Ji Kim, Y. Kim, Jeong Eun Lee, W. Chung, J. Kim, Jae-Ho Yoo   +9 more
semanticscholar   +1 more source

Evaluation of the American-English Quality of Life in Short Stature Youth (QoLISSY) questionnaire in the United States. [PDF]

, 2015
BACKGROUND: The European Quality of Life in Short Stature Youth (QoLISSY) is a novel condition-specific instrument developed to assess health related quality of life (HrQoL) in children/adolescents with short stature from patient and parent perspectives.
Bullinger, Monika, Fox, Janet, Mauras, Nelly, Newfield, Ron, Pleil, Andreas, Quitmann, Julia, Rohenkohl, Anja, Ross, Judith L., Silverman, Lawrence, Sommer, Rachel   +9 more
core   +2 more sources

Long-acting PEGylated growth hormone in children with idiopathic short stature.

European Journal of Endocrinology, 2022
OBJECTIVE To evaluate the safety and efficacy of weekly PEG-rhGH in children with idiopathic short stature (ISS) in China. DESIGN AND METHODS A multicenter, phase II study randomized subjects 1:1:1 to weekly subcutaneous injections of PEG-rhGH 0.1 (low
Xiaoping Luo, Sha Zhao, Yu Yang, G. Dong, Linqi Chen, Pin Li, F. Luo, C. Gong, Zhuangjian Xu, Xu Xu, H. Gong, H. Du, L. Hou, Y. Zhong, Q. Shi, Xuefeng Chen, Xiuli Chen, Liya Xu, R. Cheng, C. Su, Yaping Ma, Lulian Xu, Lina Zhang, Honghua Lu   +23 more
semanticscholar   +1 more source

A SHOX géndeletio előfordulása idiopathiás alacsonynövésben [PDF]

, 2017
INTRODUCTION: The isolated haploinsufficiency of the SHOX gene is one of the most common cause of short stature determined by monogenic mutations. The heterozygous deviation of the gene can be detected in 2-15% of patients with idiopathic short stature (
Bertalan R, Butz, Henriett, Csakvary V, David A, Fekete GL, Felszeghy E, Halász, Zita, Hosszú, Éva, Kun I, Luczay, Andrea, Muzsnai A, Nyírő, Gábor, Patocs, Attila, Sallai, Ágnes, Szanto Z, Tar A, Török, Dóra   +16 more
core   +2 more sources

Short stature and SHOX (Short stature homeobox) variants—efficacy of screening using various strategies [PDF]

PeerJ, 2020
Background SHOX mutations have previously been described as causes of Léri-Weill dyschondrosteosis (LWD), Langer mesomelic dysplasia (LMD), and idiopathic short stature. The loss of X chromosome—Turner syndrome or mosaic 45,X/46,XX or 46,XY—also leads to
Pavlina Capkova, Zuzana Capkova, Peter Rohon, Katerina Adamová, Jirina Zapletalova   +4 more
doaj   +2 more sources