Results 91 to 100 of about 10,067 (226)
Abstract Up‐to‐date subnational population estimates—disaggregated by age, sex, and to the lowest possible geographical level —are a key component of evidence‐based humanitarian action. In many humanitarian crises, however, large‐scale population mobility, combined with disruptions to national statistical systems, makes updating subnational population ...
Romesh Silva, Mallika Snyder
wiley +1 more source
Plaque‐type trichoblastoma and its siblings: A (follicular tumour) family history
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Ines Bertlich +4 more
wiley +1 more source
Local Tests of English in Global Contexts: A Malaysian Case Study
ABSTRACT Global tests of English are usually used globally and local tests locally. However, this global–local dichotomy has been challenged by test localisation, globalisation and glocalisation. An emerging critical question in this regard is whether local tests of English can be used locally and globally at the same time.
M. Obaidul Hamid, Mohd Faiz Mohd Yaakob
wiley +1 more source
ABSTRACT Background and Study Aims Familial adenomatous polyposis (FAP) is a genetic condition that increases the risk of developing colorectal polyposis and cancer, as well as superficial non‐ampullary duodenal epithelial tumors (SNADETs). In this single‐center retrospective study, we investigated the long‐term clinical outcomes of intensive ...
Reona Kawamura +9 more
wiley +1 more source
Conformational ensembles of the disordered 4E‐BP2:eIF4E complex restrained by smFRET experiments
Abstract Eukaryotic cap‐dependent translation initiation is regulated by binding of the predominantly folded eukaryotic initiation factor 4E (eIF4E) to the intrinsically disordered eIF4E binding proteins (4E‐BPs). Here, we report full‐length atomistic conformational ensembles generated by IDPConformerGenerator and optimized by X‐EISDv2 workflow for ...
Spencer Smyth +5 more
wiley +1 more source
Building coiled coils with polar cores
Abstract Coiled coils are formed by α‐helices winding around each other into superhelical bundles. They are characterized by a specific geometry of interaction, called knobs‐into‐holes, in which residues in the core of the structure mesh regularly along a seam that runs the length of the helices.
Marcus D. Hartmann +3 more
wiley +1 more source
Unfoldomics of human diseases: linking protein intrinsic disorder with diseases
Background Intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs) lack stable tertiary and/or secondary structure yet fulfills key biological functions.
Xue Bin +8 more
doaj +1 more source
Exploration of conformations for an IDP
Intrinsically disordered proteins (IDP) are at the center of numerous biological processes, and attract consequently extreme interest in structural biology. A systematic enumeration of protein conformations, based on distance geometry, was performed on SERF1a, a 62-residue IDP involved in interactions with amyloid peptides.
Huang, Shu-Yu +3 more
openaire +1 more source

