Results 101 to 110 of about 10,067 (226)

Impact of Stabilizing Osmolytes on the Conformational Dynamics of Human and Rat Islet Amyloid Polypeptides

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 10, Page 1717-1737, October 2026.
ABSTRACT The aggregation of human islet amyloid polypeptide (hIAPP) into cytotoxic oligomers and amyloid fibrils is a hallmark of type 2 diabetes mellitus (T2DM), leading to pancreatic β‐cell dysfunction. In contrast, rat IAPP (rIAPP) is largely non‐amyloidogenic. Osmolytes such as glucose, glycerol, and sorbitol are known to stabilize globular protein
Kiara A. Kidman, Claudio Pedrick, Cara A. Kreck, Ricardo L. Mancera   +3 more
wiley   +1 more source

Local Network Neighbourhood Effects in Foreign Direct Investment and Economic Resilience

Global Networks, Volume 26, Issue 4, October 2026.
ABSTRACT A growing literature examines the relationship between foreign direct investment (FDI) networks and economic development using measures of countries’ positions within the global investment system. While these studies provide valuable insights into the structure of international investment, they reveal little about how the configuration of ...
Bruce Cronin
wiley   +1 more source

Tracing a decade of drafting, reviewing and assessing integrated development plans in KwaZulu-Natal: Some key reflections

Town and Regional Planning, 2012
The next decade of planning in South African municipalities under democracy has dawned. The previous decade was characterised by drafting, reviewing and assessing outcomes of Integrated Development Plans (IDPs).
Mogie Subban, Henk Theron
doaj  

Internally displaced persons' ed utilization and disease patterns: A single center retrospective chart review.

PLoS ONE
BackgroundArmed conflicts profoundly disrupt healthcare systems, with internally displaced persons (IDPs) facing distinct challenges and barriers to accessing healthcare.
Eveline Hitti, Ghada Chamandi, Hiba Fadlallah, Hani Tamim, Maha Makki, Afif Mufarrij   +5 more
doaj   +1 more source

Nucleic Acids as Emerging Regulators of Calcium Phosphate Biomineralization

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
Calcium phosphate biomineralization has traditionally been considered a protein‐regulated process. This review highlights the emerging role of nucleic acids, which interact with mineral phases through adsorption, coprecipitation, and templating, thereby influencing crystal nucleation and growth.
Fanny Duhalde, Jessem Landoulsi, Xavier Houard   +2 more
wiley   +1 more source

IDPs and mobile livelihoods

Forced Migration Review, 2002
A recent research project has examined the relationsbetween internal displacement and migration in thePeruvian Andes in the second half of the 20th centuryand the difference that the introduction of the IDPconcept has meant for understanding mobile populations.
Finn Stepputat, Ninna Nyberg Sørensen
openaire   +1 more source

α‐Synuclein Aggregate‐Disassembling Compounds Prolong Survival in a Mouse Model of Parkinson's Disease

Aggregate, Volume 7, Issue 9, September 2026.
All‐D peptides that bind monomeric α‐synuclein shift the aggregation equilibrium, dismantle pathogenic fibrils, and suppress seeding activity in vitro and in cells. In a Parkinson's disease mouse model, treatment delays disease progression and extends survival, supporting direct aggregate disassembly as a disease‐modifying therapeutic strategy for ...
Sara Reithofer, Marc Sevenich, Madita Vollmer, Dila Kurtul, Laura Müller, Pelin Özdüzenciler, Laurin Gerhards, Kira Allmeroth, Mathias Wendt, Fahimeh Charbgoo, Sarah Schemmert, Marcel Naumann, Karolina Korostov, Gina Hartmann, Lothar Gremer, Gültekin Tamgüney, Dieter Willbold, Antje Willuweit   +17 more
wiley   +1 more source

Design of Involute Shape Intermediate Discharge Ports for Scroll Compressors in New Energy Vehicle Air Conditioners

Zhileng xuebao
A novel design for intermediate discharge ports (IDPs) is proposed in response to the issues of increased power consumption and reduced efficiency. This approach involved establishing a geometric model of the scroll and IDPs, focusing particularly on the
Xi Dongyang, Wang Dandong, Dong Chenyu, Li Siying, Shi Junye, Chen Jiangping   +5 more
doaj  

Inherent α‐Helix Around Tyrosine 183 in the Intrinsically Disordered Tail of the Multi‐Site Docking Platform Gab1

Biopolymers, Volume 117, Issue 5, September 2026.
The two phosphorylation sites within the Gab1 fragment 142‐203 exhibit distinct structural characteristics. Tyr162 is in a disordered region, Y183 in a helical segment. ABSTRACT The biological function of intrinsically disordered proteins is frequently coupled to short linear motifs, which serve as protein binding sites.
Anne Dietrich, Marc Lewitzky, Tobias Gruber, Jochen Balbach, Stephan M. Feller, Ulrich Weininger   +5 more
wiley   +1 more source

Deterrence, Development, and Denial: Securitising Climate‐Induced Mobility in the European Union

Contemporary European Politics, Volume 4, Issue 3, September 2026.
ABSTRACT Climate‐induced mobility poses a mounting governance challenge for the European Union (EU), where climate action, migration control, and security policy intersect in uneven and contested ways. While EU discourse frequently frames climate change as a “threat multiplier,” migration governance remains anchored in deterrence logics, producing a ...
Manasa Bollempalli
wiley   +1 more source