Results 71 to 80 of about 303,309 (299)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Data Acquisition Methodologies Utilizing Ground Penetrating Radar for Cassava (Manihot esculenta Crantz) Root Architecture

Geosciences, 2019
Cassava (Manihot esculenta Crantz), a root crop utilized as food and industrial starch product, develops and maintains its marketable product sub-surface.
Alfredo Delgado, Alexandre Novo, Dirk B. Hays   +2 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

From Religion to Kinship: The Politics of Giving in Somali Diaspora Aid Networks

Africa Spectrum
This article examines Somali diaspora humanitarianism by comparing mosque and kinship-based associations in Eastleigh, Nairobi. Drawing on ethnographic fieldwork in Eastleigh and Mogadishu – including fifty-seven interviews, four focus group discussions,
Abdirahman Edle, Peter Albrecht, Karuti Kanyinga   +2 more
doaj   +1 more source

RDTIDS: Rules and Decision Tree-Based Intrusion Detection System for Internet-of-Things Networks

Future Internet, 2020
This paper proposes a novel intrusion detection system (IDS), named RDTIDS, for Internet-of-Things (IoT) networks. The RDTIDS combines different classifier approaches which are based on decision tree and rules-based concepts, namely, REP Tree, JRip ...
Mohamed Amine Ferrag, Leandros Maglaras, Ahmed Ahmim, Makhlouf Derdour, Helge Janicke   +4 more
doaj   +1 more source

Specification: IDS Meta Data Broker

, 2020
This document describes the minimal features of an IDS Meta Data Broker, as an index-service running in conjunction with an IDS Connector. The description of the IDS Connector itself is not part of this document.
Bader, Sebastian
core   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Artificial Immune Network Clustering approach for Anomaly Intrusion Detection

Journal of Advances in Information Technology, 2012
Many Intrusion Detection approaches (IDS) have been developed in the literature. Signature based approaches for anomaly detection need to be updated with the latest signatures of unknown attacks and hence being impractical.
Murad Abdo Rassam, Mohd. Aizaini Maarof
doaj   +1 more source

Is experience with IDS predictive of IDS preference?

, 2022
In the current study, we test whether experience with infant-directed speech (IDS) predicts IDS preferences. Following an IDS preference task, infants will be sent home with a LENA recording to gauge their amount of experience with infant-directed ...
Daniela Santos Oliveira, Jessica Hay, Rebecca Robb Crum, Kenzie Mullins   +3 more
core   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source