Results 61 to 70 of about 303,309 (299)

Reducing Honeypot Log Storage Capacity Consumption – Cron Job with Perl-Script Approach

Journal of Computing Research and Innovation, 2019
Honeypot is a decoy computer system that is used to attract and monitor hackers’ activities in the network. The honeypot aims to collect information from the hackers in order to create a more secure system.
Iman Hazwam Bin Abd Halim, Nur Muhammad Irfan bin Abu Hassan, Tajul Rosli Razak, Muhammad Nabil Fikri bin Jamaluddin, Mohammad Hafiz bin Ismail   +4 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Integrating Software Engineering Processes in the Development of Efficient Intrusion Detection Systems in Wireless Sensor Networks

Sensors, 2020
Applying Software Engineering (SE) processes is vital to critical and complex systems including security and networking systems. Nowadays, Wireless Sensor Networks (WSNs) and their applications are found in many military and civilian systems which make ...
Iman Almomani, Afnan Alromi
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Sistema integrado para toma de decisiones en el diseño de estructuras de hormigón

Informes de la Construccion, 2012
El presente artículo hace una breve reflexión sobre las alternativas in situ y prefabricadas para estructuras de hormigón, justificando la necesidad de profundizar en métodos multicriterio como ayuda a la toma de decisiones.
J. Armengou, A. Aguado, G. Ormazábal
doaj   +1 more source

Accession IDs of the assemble genome sequences (IDs in gff file, description raw of fasta file and DDBJ accession IDs).

, 2023
   Accession IDs of the assemble genome sequences (IDs in gff file, description raw of fasta file and DDBJ accession IDs).
Kakeru Yokoi (5627273)
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

177LU-PSMA AND 177LU-DOTATATE AS THERAPY ALTERNATIVES FOR METACHRONOUS TRANSDIFFERENTIATED PROSTATE AND NEUROENDOCRINE TUMORS - CASE REPORT

Hematology, Transfusion and Cell Therapy
Introduction/Justification: Prostate cancer is among the most common cancers in males. The PSMA (Prostate-Specific Membrane Antigen), a protein expressed in prostate cancer cells, has been used in the control of that cancer and can also be taken up in ...
Beatriz Birelli do Nascimento, Elson Yassunaga Teshirogi, Lucas Bueno Oliveira, Lucas Nascimento Bernardes, Walter Stefatuno, Braulio Regiani Passos   +5 more
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source