Results 41 to 50 of about 303,309 (299)
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
, 2020 The Czech Research and Development and Innovation Information System is a governmental Current Research Information System (CRIS) for the Czech Republic with a good coverage of research outputs produced by Czech universities, the Academy of Sciences and other institutions.
openaire +1 more source
, 2017 This is a brochure to promote IDS' Masters courses in international development (http://www.ids.ac.uk/study)
IDS (19281550)
core +1 more source
Reinforcement Learning Applications in Cyber Security: A Review
Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2023 In the modern age we live in, the internet has become an essential part of our daily life. A significant portion of our personal data is stored online and organizations run their business online.
Murat Gök, Emine Cengiz
doaj +1 more source
IDS-15 dimension scores, weekly internet use and age of first internet use for each IA risk class.
, 2022 IDS-15 dimension scores, weekly internet use and age of first internet use for each IA risk class.
Halley M. Pontes (10268297) +3 more
core +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
IDS Postgraduate Prospectus 2020
, 2019 The Institute of Development Studies (IDS) is a global research and learning organisation for equitable and sustainable change. In partnership with the University of Sussex, IDS is ranked first in the world for development studies by the QS University ...
IDS (19281550)
core +1 more source
Journal of Forest Science, 2009 The combination of georeferenced colour aerial photos and limited field measurements of individual trees was used to determine tree stand biomass in forests of prevailing Norway spruce.
K. Matějka
doaj +1 more source