Results 101 to 110 of about 24,692 (220)

The host ubiquitin-dependent segregase VCP/p97 is required for the onset of human cytomegalovirus replication.

open access: yesPLoS Pathogens, 2017
The human cytomegalovirus major immediate early proteins IE1 and IE2 are critical drivers of virus replication and are considered pivotal in determining the balance between productive and latent infection.
Yao-Tang Lin   +2 more
doaj   +1 more source

Continuous Production of Influenza VLPs Using IC‐BEVS and Multi‐Stage Bioreactors

open access: yesBiotechnology and Bioengineering, Volume 122, Issue 4, Page 846-857, April 2025.
ABSTRACT The insect cell‐baculovirus expression vector system (IC‐BEVS) has been an asset to produce biologics for over 30 years. With the current trend in biotechnology shifting toward process intensification and integration, developing intensified processes such as continuous production is crucial to hold this platform as a suitable alternative to ...
Ricardo Correia   +7 more
wiley   +1 more source

Dissection of two modes of IE1 sub-nuclear localization in baculovirus-infected cells

open access: yesVirus Research, 2015
Prior to viral DNA replication, baculovirus IE1 exhibits a focal distribution within the cell nucleus. During DNA replication, the IE1 foci apparently expand and develop into a virus replication center called the virogenic stroma (VS). In our search for chemical compounds capable of modulating Bombyx mori nucleopolyhedrovirus (BmNPV: a prototype of ...
Toshihiro, Nagamine   +3 more
openaire   +2 more sources

Alzheimer's disease‐associated CD83(+) microglia are linked with increased immunoglobulin G4 and human cytomegalovirus in the gut, vagal nerve, and brain

open access: yesAlzheimer's &Dementia, Volume 21, Issue 1, January 2025.
Abstract INTRODUCTION While there may be microbial contributions to Alzheimer's disease (AD), findings have been inconclusive. We recently reported an AD‐associated CD83(+) microglia subtype associated with increased immunoglobulin G4 (IgG4) in the transverse colon (TC).
Benjamin P. Readhead   +40 more
wiley   +1 more source

Rings of Invariant Module Type and Automorphism-Invariant Modules [PDF]

open access: yes, 2012
A module is called automorphism-invariant if it is invariant under any automorphism of its injective hull. In [Algebras for which every indecomposable right module is invariant in its injective envelope, Pacific J. Math., vol. 31, no.
Ashish, K. Srivastava, Surjeet Singh
core  

Rab Proteins as Potential Therapeutic Targets Applied to Crustacean Aquaculture: Rab7 Case Analysis

open access: yesReviews in Aquaculture, Volume 17, Issue 1, January 2025.
ABSTRACT Rab proteins constitute an important subfamily of molecular effectors whose function is related to the modulation of several important cellular and metabolic processes, including controlling intracellular endocytic vesicle trafficking, phagosome formation, endosome maturation, and innate immunity. In crustaceans, the study and characterization
Carlos Fajardo   +6 more
wiley   +1 more source

The Role of RhoA, RhoB and RhoC GTPases in Cell Morphology, Proliferation and Migration in Human Cytomegalovirus (HCMV) Infected Glioblastoma Cells

open access: yesCellular Physiology and Biochemistry, 2016
Background/Aims: Rho GTPases are crucial regulators of the actin cytoskeleton, membrane trafficking and cell signaling and their importance in cell migration and invasion is well- established.
Melpomeni Tseliou   +5 more
doaj   +1 more source

An arithmetic intersection formula for denominators of Igusa class polynomials

open access: yes, 2015
In this paper we prove an explicit formula for the arithmetic intersection number (CM(K).G1)_{\ell} on the Siegel moduli space of abelian surfaces, generalizing the work of Bruinier-Yang and Yang.
Lauter, Kristin, Viray, Bianca
core   +1 more source

Directed percolation with incubation times

open access: yes, 2006
We introduce a model for directed percolation with a long-range temporal diffusion, while the spatial diffusion is kept short ranged. In an interpretation of directed percolation as an epidemic process, this non-Markovian modification can be understood ...
Andrea Jiménez-Dalmaroni   +4 more
core   +1 more source

The Early Baculovirus he65 Promoter: On the Mechanism of Transcriptional Activation by IE1

open access: yesVirology, 1998
We have initiated studies on the mechanism of early transcriptional activation of the early he65 promoter during infection with Autographa californica multicapsid nuclear polyhedrosis virus. This analysis is based on a comparison of the sequences required for he65 promoter activation with those sequences that support specific protein binding.
Kremer, Andreas   +1 more
openaire   +2 more sources

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