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N6-methyladenosine modification of HCMV IE1 transcript promotes the repressive state of viral genome to achieve latent infection.

Proceedings of the National Academy of Sciences of the United States of America
Human cytomegalovirus (HCMV) is a prevalent pathogen that chronically infects the majority of human population. Among the many features that allow such widespread HCMV infection, one is its ability to maintain a transcriptionally dormant immune-evasive ...
H. Jeong   +5 more
semanticscholar   +1 more source

Controlled crystal dehydration triggers a space-group switch and shapes the tertiary structure of cytomegalovirus immediate-early 1 (IE1) protein.

Acta Crystallographica Section D: Biological Crystallography, 2015
Cytomegalovirus immediate-early 1 (IE1) protein is a key viral effector protein that reprograms host cells. Controlled dehydration experiments with IE1 crystals not only extended their diffraction limit from 2.85 to 2.3 Å resolution but also triggered a ...
S. Klingl   +3 more
semanticscholar   +1 more source

The human cytomegalovirus IE1 protein: past and present developments

, 2014
:  Human cytomegalovirus (HCMV), a member of the β-herpesvirus subfamily, is an important pathogen that infects the majority of the human population.
Myriam Scherer, T. Stamminger
semanticscholar   +1 more source

Shrimp SIRT1 activates of the WSSV IE1 promoter independently of the NF-κB binding site.

Fish and Shellfish Immunology, 2020
Zi-Ning Kao   +5 more
semanticscholar   +1 more source

Chemical Complementarity of Blood-Sourced, Breast Cancer-Related TCR CDR3s and the CMV UL29 and IE1 Antigens is Associated with Worse Overall Survival.

Biochemical Genetics
Pooja Neerumalla   +8 more
semanticscholar   +1 more source

The Human CMV IE1 Protein: An Offender of PML Nuclear Bodies.

Advances in Anatomy, Embryology and Cell Biology, 2017
Myriam Scherer   +2 more
semanticscholar   +1 more source

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