Results 41 to 50 of about 19,338 (133)

HCMV IE1/IE1mut Therapeutic Vaccine Induces Tumor Regression via Intratumoral Tertiary Lymphoid Structure Formation and Peripheral Immunity Activation in Glioblastoma Multiforme

open access: yesMolecular Neurobiology
Glioblastoma multiforme (GBM), a highly malignant invasive brain tumor, is associated with poor prognosis and survival and lacks an effective cure. High expression of the human cytomegalovirus (HCMV) immediate early protein 1 (IE1) in GBM tissues is ...
Xiaoli Yang   +10 more
semanticscholar   +1 more source

Redistribution of critical major histocompatibility complex and T cell receptor-binding functions of residues in an antigenic sequence after biterminal substitution [PDF]

open access: yes, 1991
Residues critical for establishing a trimolecular interaction with a major histocompatibility complex (MHC)-encoded receptor and a T cell antigen receptor (TcR) were determined for an antigenic nonapeptide. The N-terminal residue proved to be involved in
Allen   +18 more
core   +1 more source

Killer cell proteases can target viral immediate-early proteins to control human cytomegalovirus infection in a noncytotoxic manner.

open access: yesPLoS Pathogens, 2020
Human cytomegalovirus (HCMV) is the most frequent viral cause of congenital defects and can trigger devastating disease in immune-suppressed patients. Cytotoxic lymphocytes (CD8+ T cells and NK cells) control HCMV infection by releasing interferon-γ and ...
Liling Shan   +12 more
doaj   +1 more source

Method of generalized Reynolds operators in Clifford algebras

open access: yes, 2020
We develop the method of averaging in Clifford algebras suggested by the author in the previous papers. Namely, we introduce generalized Reynolds operators in real and complexified Clifford algebras of arbitrary dimension and signature and prove a number
Shirokov, D. S.
core   +1 more source

Neutralizing Monoclonal Antibodies Reduce Human Cytomegalovirus Infection and Spread in Developing Placentas. [PDF]

open access: yes, 2019
Congenital human cytomegalovirus (HCMV) infection is a leading cause of birth defects worldwide, yet the most effective strategies for preventing virus transmission during pregnancy are unknown.
An, Zhiqiang   +8 more
core   +1 more source

Effects of Early or Overexpression of the Autographa californica Multiple Nucleopolyhedrovirus orf94 (ODV-e25) on Virus Replication. [PDF]

open access: yesPLoS ONE, 2013
odv-e25(e25) is one of the core genes of baculoviruses. To investigate how it functions in the replication cycle of a baculovirus, a number of Autographa californica multiple nucleopolyhedrovirus recombinants with e25 under control of the promoter of ...
Xiao-Chun Luo   +5 more
doaj   +1 more source

Quantum data processing and error correction [PDF]

open access: yes, 1996
This paper investigates properties of noisy quantum information channels. We define a new quantity called {\em coherent information} which measures the amount of quantum information conveyed in the noisy channel.
A. Wehrl   +14 more
core   +3 more sources

Computational modeling of acute myocardial infarction [PDF]

open access: yes, 2016
This is an Accepted Manuscript of an article published by Taylor & Francis Group in Computer Methods in Biomechanics and Biomedical Engineering on October, 2016, available online at: http://www.tandfonline.com/10.1080/10255842.2015.1105965Myocardial ...
Kuhl, E., Sáez Viñas, Pablo
core   +2 more sources

The Promyelocytic Leukemia Protein facilitates human herpesvirus 6B chromosomal integration, immediate-early 1 protein multiSUMOylation and its localization at telomeres.

open access: yesPLoS Pathogens, 2020
Human herpesvirus 6B (HHV-6B) is a betaherpesvirus capable of integrating its genome into the telomeres of host chromosomes. Until now, the cellular and/or viral proteins facilitating HHV-6B integration have remained elusive. Here we show that a cellular
Vanessa Collin   +3 more
doaj   +1 more source

Assessment of the T-SPOT.CMV interferon-γ release assay in renal transplant recipients: A single center cohort study. [PDF]

open access: yesPLoS ONE, 2018
The measurement of CMV specific cellular immunity in organ transplant recipients could contribute additional acuity to serology based, CMV infection risk stratification, facilitating optimisation of immunosuppression and anti-viral prophylaxis.A pilot ...
Dimitrios Chanouzas   +3 more
doaj   +1 more source

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