Results 61 to 70 of about 19,338 (133)

Identification of compounds with anti-human cytomegalovirus activity that inhibit production of IE2 proteins [PDF]

open access: yes, 2017
Using a high throughput screening methodology we surveyed a collection of largely uncharacterized validated or suspected kinase inhibitors for anti-human cytomegalovirus (HCMV) activity.
Beelontally, Rooksarr   +10 more
core   +2 more sources

Human Cytomegalovirus Antigen Presentation by HLA‐G in Infected Cells

open access: yesHLA, Volume 105, Issue 5, May 2025.
ABSTRACT HLA‐E and ‐G class Ib molecules were considered unrelated to viral antigen presentation. HLA‐E binds nonamers from the leader sequences of other HLA‐I molecules and the human cytomegalovirus (HCMV) UL40 protein, interacting with CD94/NKG2 NK cell receptors.
Mireia Altadill   +11 more
wiley   +1 more source

Host immune response to cytomegalovirus [PDF]

open access: yes, 1987
To confirm that immediate-early (IE) genes of murine cytomegalovirus (MCMV) give rise to antigens recognized by specific cytolytic T lymphocytes (CTL), a 10.8-kilobase fragment of MCMV DNA which is abundantly transcribed at IE times was transfected into ...
Keil, Günther M.   +3 more
core  

Quaternionic factorization of the Schroedinger operator and its applications to some first order systems of mathematical physics

open access: yes, 2003
We consider the following first order systems of mathematical physics. 1.The Dirac equation with scalar potential. 2.The Dirac equation with electric potential. 3.The Dirac equation with pseudoscalar potential.
Babich V M   +24 more
core   +1 more source

Continuous Production of Influenza VLPs Using IC‐BEVS and Multi‐Stage Bioreactors

open access: yesBiotechnology and Bioengineering, Volume 122, Issue 4, Page 846-857, April 2025.
ABSTRACT The insect cell‐baculovirus expression vector system (IC‐BEVS) has been an asset to produce biologics for over 30 years. With the current trend in biotechnology shifting toward process intensification and integration, developing intensified processes such as continuous production is crucial to hold this platform as a suitable alternative to ...
Ricardo Correia   +7 more
wiley   +1 more source

Alzheimer's disease‐associated CD83(+) microglia are linked with increased immunoglobulin G4 and human cytomegalovirus in the gut, vagal nerve, and brain

open access: yesAlzheimer's &Dementia, Volume 21, Issue 1, January 2025.
Abstract INTRODUCTION While there may be microbial contributions to Alzheimer's disease (AD), findings have been inconclusive. We recently reported an AD‐associated CD83(+) microglia subtype associated with increased immunoglobulin G4 (IgG4) in the transverse colon (TC).
Benjamin P. Readhead   +40 more
wiley   +1 more source

The Human Cytomegalovirus Major Immediate-Early Proteins as Antagonists of Intrinsic and Innate Antiviral Host Responses

open access: yesViruses, 2009
The major immediate-early (IE) gene of human cytomegalovirus (CMV) is believed to have a decisive role in acute infection and its activity is an important indicator of viral reactivation from latency.
Michael Nevels, Christina Paulus
doaj   +1 more source

Infection of human cytomegalovirus in cultured human gingival tissue. [PDF]

open access: yes, 2006
BackgroundHuman cytomegalovirus (HCMV) infection in the oral cavity plays an important role in its horizontal transmission and in causing viral-associated oral diseases such as gingivitis.
Chu, Alice   +5 more
core   +3 more sources

Rab Proteins as Potential Therapeutic Targets Applied to Crustacean Aquaculture: Rab7 Case Analysis

open access: yesReviews in Aquaculture, Volume 17, Issue 1, January 2025.
ABSTRACT Rab proteins constitute an important subfamily of molecular effectors whose function is related to the modulation of several important cellular and metabolic processes, including controlling intracellular endocytic vesicle trafficking, phagosome formation, endosome maturation, and innate immunity. In crustaceans, the study and characterization
Carlos Fajardo   +6 more
wiley   +1 more source

Tightly regulated expression of Autographa californica multicapsid nucleopolyhedrovirus immediate early genes emerges from their interactions and possible collective behaviors. [PDF]

open access: yesPLoS ONE, 2015
To infect their hosts, DNA viruses must successfully initiate the expression of viral genes that control subsequent viral gene expression and manipulate the host environment.
Chikako Ono   +5 more
doaj   +1 more source

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