Results 61 to 70 of about 24,692 (220)
Transcriptional activation of endoplasmic reticulum chaperone GRP78 by HCMV IE1-72 protein [PDF]
Cell Research, 2011 Glucose-regulated protein 78 (GRP78), a key regulator of endoplasmic reticulum (ER) stress, facilitates cancer cell growth and viral replication. The mechanism leading to grp78 gene activation during viral infection is largely unknown. In this study, we show that the immediate-early 1 (IE1-72) protein of the human cytomegalovirus (HCMV) is essential ...
Derick, Shi-Chen Ou +5 more
openaire +2 more sources
Effects of Early or Overexpression of the Autographa californica Multiple Nucleopolyhedrovirus orf94 (ODV-e25) on Virus Replication. [PDF]
PLoS ONE, 2013 odv-e25(e25) is one of the core genes of baculoviruses. To investigate how it functions in the replication cycle of a baculovirus, a number of Autographa californica multiple nucleopolyhedrovirus recombinants with e25 under control of the promoter of ...
Xiao-Chun Luo +5 more
doaj +1 more source
Host immune response to cytomegalovirus [PDF]
, 1987 To confirm that immediate-early (IE) genes of murine cytomegalovirus (MCMV) give rise to antigens recognized by specific cytolytic T lymphocytes (CTL), a 10.8-kilobase fragment of MCMV DNA which is abundantly transcribed at IE times was transfected into ...
Keil, Günther M. +3 more
core
Advanced Science, EarlyView.This study finds that CD8⁺ TSCM cells exhibit superior self‐renewal, differentiation, and antiviral activity. Transcriptome and epigenome analyses highlight MAPK cascade regulation in TSCM cells. In vivo, virus‐specific TSCM cells show enhanced persistence and tumor protection.
Xun‐Hong Cao +13 more
wiley +1 more source
PLoS Pathogens, 2020 Human herpesvirus 6B (HHV-6B) is a betaherpesvirus capable of integrating its genome into the telomeres of host chromosomes. Until now, the cellular and/or viral proteins facilitating HHV-6B integration have remained elusive. Here we show that a cellular
Vanessa Collin +3 more
doaj +1 more source
Structural organization, expression, and functional characterization of the murine cytomegalovirus immediate-early gene 3. [PDF]
, 1992 We have previously defined ie3 as a coding region located downstream of the ie1 gene which gives rise to a 2.75-kb immediate-early (IE) transcript. Here we describe the structural organization of the ie3 gene, the amino acid sequence of the gene product,
Bühler, Bernhard +3 more
core +1 more source
Method of generalized Reynolds operators in Clifford algebras
, 2020 We develop the method of averaging in Clifford algebras suggested by the author in the previous papers. Namely, we introduce generalized Reynolds operators in real and complexified Clifford algebras of arbitrary dimension and signature and prove a number
Shirokov, D. S.
core +1 more source
Plethysm and fast matrix multiplication [PDF]
, 2018 Motivated by the symmetric version of matrix multiplication we study the plethysm $S^k(\mathfrak{sl}_n)$ of the adjoint representation $\mathfrak{sl}_n$ of the Lie group $SL_n$.
Seynnaeve, Tim
core +3 more sources
Circular Economy: A Pathway to Integrated Value Creation for Business and Society
Business Strategy and the Environment, EarlyView.ABSTRACT Amid growing environmental pressures and the pressing demand to advance sustainable development, the circular economy (CE) has positioned itself as a transformative business approach capable of safeguarding favourable ecosystem conditions through the application of key R‐strategies.
Saudi‐Yulieth Enciso‐Alfaro +1 more
wiley +1 more source
Assessment of the T-SPOT.CMV interferon-γ release assay in renal transplant recipients: A single center cohort study. [PDF]
PLoS ONE, 2018 The measurement of CMV specific cellular immunity in organ transplant recipients could contribute additional acuity to serology based, CMV infection risk stratification, facilitating optimisation of immunosuppression and anti-viral prophylaxis.A pilot ...
Dimitrios Chanouzas +3 more
doaj +1 more source