Improving uptake of Fracture Prevention drug treatments: a protocol for Development of a consultation intervention (iFraP-D) [PDF]
BMJ Open, 2021 Introduction Prevention of fragility fractures, a source of significant economic and personal burden, is hindered by poor uptake of fracture prevention medicines.
Stephen Robert Chapman +15 more
doaj +2 more sources
A person-centred consultation intervention to improve shared decision-making about, and uptake of, osteoporosis medicines (iFraP): a pragmatic, parallel-group, individual randomised controlled trial protocol [version 3; peer review: 3 approved, 1 approved with reservations] [PDF]
NIHR Open ResearchBackground Good quality shared decision-making (SDM) conversations involve people with, or at risk of osteoporosis and clinicians collaborating to decide, where appropriate, which evidence-based medicines best fit the person’s life, beliefs, and values ...
Terence W O'Neill +26 more
doaj +2 more sources
Protocol for a mixed methods process evaluation for a randomised controlled trial to improve shared decision-making about, and uptake of, osteoporosis medicines: the iFraP study [version 3; peer review: 2 approved, 1 approved with reservations] [PDF]
NIHR Open ResearchBackground High quality shared decision-making (SDM) conversations involve people with or at risk of osteoporosis and clinicians working together to decide, where appropriate, which evidence-based medicines best fit the person’s life, beliefs, and values.
Terence W O'Neill +14 more
doaj +2 more sources
Chaperones for dancing on chromatin: Role of post-translational modifications in dynamic damage detection hand-offs during nucleotide excision repair. [PDF]
Bioessays, 2021 UV‐DDB (only DDB2 shown) initiates global‐genome nucleotide excision repair by recognizing photoproducts in chromatin. If UV‐DDB lingers too long at damage sites, as part of DDB1‐CUL4A‐RBX E3 ligase, UV‐DDB ubiquitylates itself on Lys residues enabling VCP to dissociate it and allow XPC and TFIIH to bind to the lesion.
Van Houten B, Schnable B, Kumar N.
europepmc +2 more sources
Abstracts from the Osteoporosis 2023 Conference, Royal Osteoporosis Society, September 13–14, University of Manchester, UK [PDF]
JBMR Plus, 2023 JBMR Plus, Volume 7, Issue S6, September 2023.
europepmc +2 more sources
Developing a model Fracture Liaison Service consultation with patients, carers and clinicians: a Delphi survey to inform content of the iFraP complex consultation intervention [PDF]
Archives of Osteoporosis, 2021 Laurna Bullock +2 more
exaly +2 more sources
Variation in UK fracture liaison service consultation conduct and content before and during the COVID pandemic: results from the iFraP-D UK survey [PDF]
Archives of Osteoporosis, 2023 Laurna Bullock +2 more
exaly +2 more sources
Exploring practice and perspectives on shared decision-making about osteoporosis medicines in Fracture Liaison Services: the iFraP development qualitative study [PDF]
Archives of OsteoporosisLaurna Bullock +2 more
exaly +2 more sources
Increasing spatial resolution of photoregulated GTPases through immobilized peripheral membrane proteins [PDF]
Small GTPases, 2020 Theodorus W J Gadella
exaly +2 more sources
Journal of Innovative Optical Health Sciences, 2021 Fluorescence recovery after photobleaching (FRAP) and single particle tracking (SPT) techniques determine the diffusion coefficient from average diffusive motion of high-concentration molecules and from trajectories of low-concentration single molecules,
Donghee Lee +2 more
doaj +1 more source