IgA anti-CD74 autoantibodies are associated with treatment escalation in peripheral psoriatic arthritis. [PDF]
Elsaghir A +5 more
europepmc +1 more source
Sequence of Immunological Events During IgE‐Mediated Allergic Reactions to Food
ABSTRACT Food allergies (FA) represent a significant global health burden. Upon allergen re‐exposure, allergic patients exhibit a sequence of symptoms that vary in terms of affected organ systems, severity, time of onset and allergen reactivity thresholds.
N. A. Nagy +7 more
wiley +1 more source
Cooperative control of IgA synthesis and secretion by MZB1 and the J chain. [PDF]
Cui C +8 more
europepmc +1 more source
This study established a microarray containing a representative panel of purified Blo t and Der p allergens for the identification of patients sensitised to Blo t and/or Der p. Results indicate that the microarray based on Blo t and Der p allergens is a useful tool for the identification of Blo t‐ and/or Der p‐sensitised patients. The microarray may be
Nishelle Dsouza +16 more
wiley +1 more source
Gut microbial IgA coating in infants with traditional farming lifestyle and urban infants with allergic outcomes. [PDF]
Bu K +13 more
europepmc +1 more source
Integrated Clinical Trial and Molecular Profiling Reveals Immune Drivers of Chronic Hand Eczema
This study performed an unbiased molecular profiling of CHE patients across diverse etiologies to identify shared pathogenic drivers and evaluate the impact of IL‐4Rα blockade via dupilumab over 16 weeks. CHE shows a mixed immune signature involving type 1, 2, and 3 pathways with features of atopic dermatitis and psoriasis.
Perrine Gery +25 more
wiley +1 more source
Independent association of serum IgA levels with moderate-to-severe obstructive sleep apnea in children with adenotonsillar hypertrophy. [PDF]
Xia F, Xia Z, Huang T, Li D.
europepmc +1 more source
Case Report: A rare co-occurrence of IgA pemphigus and pyoderma gangrenosum associated with IgA-κ type monoclonal gammopathy of undetermined significance: a 19-year diagnostic and therapeutic journey. [PDF]
Xie Y, Liu X, Wu J, Chen L, Chen J.
europepmc +1 more source
IL‐33 induces inflammatory gene signatures in eosinophils, characterised by the upregulation of cell surface markers, inflammatory mediators and regulatory factors, all of which were also observed in nasal polyp‐derived eosinophils. Ox‐LDL and complement fragments (C3a and C5a) promote eosinophil adhesion and survival.
Emiko Matsuyama +16 more
wiley +1 more source

