Results 61 to 70 of about 502,516 (332)

Why low-dose aspirin persists in recurrent pregnancy loss without APS: cognitive bias and system design

open access: yesAJOG Global Reports
Low-dose aspirin (LDA) is widely prescribed for recurrent pregnancy loss (RPL) even when antiphospholipid syndrome (APS) is absent, despite high-level evidence showing no improvement in live-birth rate in such cases.
Kentaro Iga, MD   +2 more
doaj   +1 more source

Electrically Readable Lateral Flow Assay Using Organic Transistors for Diagnostic Applications

open access: yesAdvanced Materials, EarlyView.
Electrolyte‐gated organic field‐effect transistors (EGOFETs) are integrated with lateral flow (LF) paper fluidics to create a reusable, portable, and low‐cost point‐of‐care (PoC) diagnostic test. The devices are validated for Human Immunoglobulin G detection, achieving high sensitivity (0.1 fm), selectivity, and reproducibility with rapid results in 20–
María Jesús Ortiz‐Aguayo   +4 more
wiley   +1 more source

IgA-enhancing effects of membrane vesicles derived from Lactobacillus sakei subsp. sakei NBRC15893 [PDF]

open access: yes, 2018
Immunoglobulin (Ig) A in the mucus of the intestinal tract plays an important role in preventing the invasion of pathogenic microorganisms and regulating the composition of the gut microbiota.
Katakura Yoshio   +7 more
core   +2 more sources

Multi‐Material Additive Manufacturing of Soft Robotic Systems: A Comprehensive Review

open access: yesAdvanced Robotics Research, EarlyView.
This review explores the transformative role of multi‐material additive manufacturing (MMAM) in the development of soft robotic systems. It presents current techniques, materials, and design strategies that enable functionally graded and adaptive structures.
Ritik Raj   +2 more
wiley   +1 more source

Assessment of infiltration and erosion rates in Mediterranean reservoirs’ catchments through rainfall simulation

open access: yesInternational Journal of Sediment Research
The land use and vegetation type of a reservoir's catchment substantially affect the hydrological processes of soil infiltration and runoff. They also act as drivers or constraints for erosive processes. All the previous processes influence the amount of
Jorge Mongil-Manso   +7 more
doaj   +1 more source

Adaptive 2D IGA boundary element methods

open access: yes, 2015
We derive and discuss a posteriori error estimators for Galerkin and collocation IGA boundary element methods for weakly-singular integral equations of the first-kind in 2D.
Feischl, Michael   +3 more
core   +2 more sources

Quantitative Proteomics and CRISPR/Cas9 Editing Reveal UPR‐Mediated Control of Immunoglobulin Homeostasis in Hybridomas

open access: yesAdvanced Science, EarlyView.
BCR sequencing and subclone analysis correlated immunoglobulin (Ig) chain loss in dysfunctional hybridomas with disrupted monoclonal antibody homeostasis. Proteomics‐guided CRISPR/Cas9 editing revealed that the unfolded protein response (UPR) regulates aberrant Ig synthesis.
Rubing Zou   +9 more
wiley   +1 more source

Event-based Bayesian causal modelling for flood hydrograph prediction, Upper Andarax intermittent stream, Spain

open access: yesJournal of Hydrology: Regional Studies, 2022
Study region: The study region comprises an intermittent stream named Upper Andarax, within a semi-arid watershed in SE Spain (Andarax river basin), characterised by uneven topography and its striking hydraulic heritage.
Mohamed Hamitouche, Jose-Luis Molina
doaj   +1 more source

Space-Time Isogeometric Analysis of Parabolic Evolution Equations [PDF]

open access: yes, 2015
We present and analyze a new stable space-time Isogeometric Analysis (IgA) method for the numerical solution of parabolic evolution equations in fixed and moving spatial computational domains.
Langer, Ulrich   +2 more
core   +1 more source

CD20+FCRL4+ B Cells Activate CD8+ T Cells via MHC‐I Restriction in Nasopharyngeal Carcinoma Anti‐Tumor Immunity

open access: yesAdvanced Science, EarlyView.
CD20⁺FCRL4⁺ B cells in nasopharyngeal carcinoma actively cross‐present exogenous tumor antigens via MHC‐I, enhancing CD8⁺ T‐cell activation, memory formation, and cytotoxicity. IFNγ‐driven WDFY4 upregulation facilitates this process. These findings reveal an unconventional B‐cell–mediated antitumor mechanism and indicate potential relevance to ...
Benjian Zhang   +17 more
wiley   +1 more source

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