Results 51 to 60 of about 465,656 (285)

HUMORAL IMMUNOLOGICAL PARAMETERS IN SMOKING AND NON-SMOKING PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE

Туберкулез и болезни лёгких, 2014
Quantitative changes in immunoglobulins A (IgA), IgE, IgG, IgM, and B lymphocytes in peripheral blood were estimated in non-smoking and smoking patients with chronic obstructive pulmonary disease (COPD).
A. G. Kadushkin, L. V. Kartun, E. V. Khodosovskaya, A. V. Goncharik, A. D. Taganovich   +4 more
doaj   +1 more source

Omega-3 fatty acid intake suppresses induction of diverse autoantibody repertoire by crystalline silica in lupus-prone mice

Autoimmunity, 2020
Inhalation of crystalline silica (cSiO2) in the workplace is etiologically linked to lupus and other autoimmune diseases. Exposing lupus-prone NZBWF1 mice to respirable cSiO2 unleashes a vicious cycle of inflammation and cell death in the lung that ...
Lichchavi D. Rajasinghe, Quan-Zhen Li, Chengsong Zhu, Mei Yan, Preeti S. Chauhan, Kathryn A. Wierenga, Melissa A. Bates, Jack R. Harkema, Abby D. Benninghoff, James J. Pestka   +9 more
doaj   +1 more source

Performance Characteristics of Anti–Collagen II Antibodies in Relapsing Polychondritis and Related Diseases: Prospective Analysis, Systematic Review, and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective Relapsing polychondritis (RP) is a rare disease defined by recurrent cartilaginous inflammation. Anti–collagen II (Col2) antibodies have been proposed as a diagnostic biomarker for RP, but their performance characteristics are not well defined.
Karyssa Stonick, Marcela A. Ferrada, Alice Fike, Kaitlin A. Quinn, Benjamin A. Turturice, Casey Stein, Peter C Grayson   +6 more
wiley   +1 more source

Enzymatically synthesized exopolysaccharide of a probiotic strain Leuconostoc mesenteroides NTM048 shows adjuvant activity to promote IgA antibody responses

Gut Microbes, 2021
Leuconostoc mesenteroides strain NTM048 produces an exopolysaccharide (EPS; glucose polymers 94% and fructose polymers 6%) with adjuvanticity for mucosal vaccination.
Chiaki Matsuzaki, Yukari Nakashima, Ikuto Endo, Yusuke Tomabechi, Yasuki Higashimura, Saki Itonori, Koji Hosomi, Jun Kunisawa, Kenji Yamamoto, Keiko Hisa   +9 more
doaj   +1 more source

Experience with dupilumab in patients with atopic dermatitis

Аллергология и Иммунология в Педиатрии, 2023
According to recent data, the key molecules in the pathogenesis of atopic dermatitis are the cytokines IL-4 and IL-13, which initiate and maintain Th2 inflammation.
E. A. Glukhova, E. D. Kuvshinova, V. A. Revyakina   +2 more
doaj   +1 more source

What do Topologists want from Seiberg--Witten theory? (A review of four-dimensional topology for physicists)

, 2002
In 1983, Donaldson shocked the topology world by using instantons from physics to prove new theorems about four-dimensional manifolds, and he developed new topological invariants.
KEVIN IGA, Seiberg N.
core   +1 more source

IgA nephropathy

Kidney International, 1995
IgAN is the most common type of glomerulonephritis worldwide, and is found more in men and distinctly less in blacks. It presents with macroscopic hematuria in about 40 to 45% of patients, with microscopic hematuria and proteinuria in about 35 to 40%, and with nephrotic syndrome or acute renal failure in the remainder.
openaire   +2 more sources

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients With Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner, Jordi Antón, Inmaculada Calvo‐Penadés, Richard Dimelow, Gerd Horneff, Sylvia Kamphuis, Rebecca Marino, Andre van Maurik, Kirsten Minden, Masaaki Mori, Josephine Ocran‐Appiah, Christel Wilkinson, Yuichi Yamasaki, Deepak Assudani, for the Pediatric Rheumatology Collaborative Study Group (PRCSG) and Paediatric Rheumatology International Trials Organisation (PRINTO) Network investigators   +14 more
wiley   +1 more source

Diagnostic Use of Testing for Novel Murine Autoantibodies for Sjögren Disease in the Rheumatology Outpatient Setting

Arthritis Care &Research, EarlyView.
Objective The goal was to assess the diagnostic performance of three novel autoantibodies (NA) for Sjögren disease (SjD) by comparing NA prevalence in patients with SjD, other autoimmune rheumatic diseases (ARDs), nonspecific chronic sialadenitis (CS), and controls.
Chadwick R. Johr, Michael D. George, Vatinee Y. Bunya, Nora Sandorfi, Mina Massaro‐Giordano, Frederick B. Vivino   +5 more
wiley   +1 more source

Why low-dose aspirin persists in recurrent pregnancy loss without APS: cognitive bias and system design

AJOG Global Reports
Low-dose aspirin (LDA) is widely prescribed for recurrent pregnancy loss (RPL) even when antiphospholipid syndrome (APS) is absent, despite high-level evidence showing no improvement in live-birth rate in such cases.
Kentaro Iga, MD, Takeshi Murakoshi, MD, PhD, Hiroshi Adachi, MD, PhD   +2 more
doaj   +1 more source