Results 61 to 70 of about 465,656 (285)

Cracking the Code: Which Ocular Symptoms Predict Dry Eye Signs? Insights from a large international sicca registry

open access: yesArthritis Care &Research, Accepted Article.
Purpose The study aimed to identify symptom‐based predictors of dry eye disease (DED) signs in the Sjögrens International Collaborative Clinical Alliance (SICCA) cohort. Methods Retrospective analysis examining 16 ocular symptoms (most graded 0‐4) and artificial tear (AT) use (graded 0‐3) as predictors of DED signs [abnormal ocular surface staining ...
Pragnya R Donthineni   +7 more
wiley   +1 more source

Isogeometric Simulation and Shape Optimization with Applications to Electrical Machines [PDF]

open access: yes, 2018
Future e-mobility calls for efficient electrical machines. For different areas of operation, these machines have to satisfy certain desired properties that often depend on their design. Here we investigate the use of multipatch Isogeometric Analysis (IgA)
Gangl, Peter   +3 more
core   +4 more sources

Enhanced Human Antigen‐Specific B Cell Responses Using In Vitro 3D Tonsil Cultures Containing Stromal Cells

open access: yesAdvanced Healthcare Materials, EarlyView.
We developed a fully human 3D tonsil cell culture system incorporating supportive stromal cells that better sustains and activates immune cells than conventional methods. The model generates stronger, more targeted antibody responses to viral antigens and vaccines, providing a physiologically relevant and entirely human platform for studying immune ...
Maaike V. J. Braham   +11 more
wiley   +1 more source

Assessment of infiltration and erosion rates in Mediterranean reservoirs’ catchments through rainfall simulation

open access: yesInternational Journal of Sediment Research
The land use and vegetation type of a reservoir's catchment substantially affect the hydrological processes of soil infiltration and runoff. They also act as drivers or constraints for erosive processes. All the previous processes influence the amount of
Jorge Mongil-Manso   +7 more
doaj   +1 more source

IgA-enhancing effects of membrane vesicles derived from Lactobacillus sakei subsp. sakei NBRC15893 [PDF]

open access: yes, 2018
Immunoglobulin (Ig) A in the mucus of the intestinal tract plays an important role in preventing the invasion of pathogenic microorganisms and regulating the composition of the gut microbiota.
Katakura Yoshio   +7 more
core   +2 more sources

Electrically Readable Lateral Flow Assay Using Organic Transistors for Diagnostic Applications

open access: yesAdvanced Materials, EarlyView.
Electrolyte‐gated organic field‐effect transistors (EGOFETs) are integrated with lateral flow (LF) paper fluidics to create a reusable, portable, and low‐cost point‐of‐care (PoC) diagnostic test. The devices are validated for Human Immunoglobulin G detection, achieving high sensitivity (0.1 fm), selectivity, and reproducibility with rapid results in 20–
María Jesús Ortiz‐Aguayo   +4 more
wiley   +1 more source

GOAT MILK PRODUCTION UNDER ORGANIC FARMING STANDARS

open access: yesTropical and Subtropical Agroecosystems, 2009
Organic farming has emerged from its niche. This holds true for organic goat milk, yoghurt and cheese as well. Particularly in the EU many dairy goat farms have converted or want to convert towards organic farming to profit from the positive image and ...
Gerold Hartmut Rahmann
doaj  

Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan   +17 more
wiley   +1 more source

Event-based Bayesian causal modelling for flood hydrograph prediction, Upper Andarax intermittent stream, Spain

open access: yesJournal of Hydrology: Regional Studies, 2022
Study region: The study region comprises an intermittent stream named Upper Andarax, within a semi-arid watershed in SE Spain (Andarax river basin), characterised by uneven topography and its striking hydraulic heritage.
Mohamed Hamitouche, Jose-Luis Molina
doaj   +1 more source

Multicohort Validation of Gut Microbiome Signatures for Cholangiocarcinoma Diagnosis and Functional Characterization of Bifidobacterium Pseudocatenulatum

open access: yesAdvanced Science, EarlyView.
This study analyzes gut bacteria in cholangiocarcinoma patients, revealing distinct microbial signatures that enable accurate disease detection. Species‐based diagnostic models achieved over 98% accuracy in identifying cholangiocarcinoma and distinguished it from other liver diseases. The research demonstrates that specific beneficial bacteria suppress
Benchen Rao   +18 more
wiley   +1 more source

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