Results 151 to 160 of about 25,586 (182)
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BioDrugs, 1998
IgA nephropathy is the commonest form of glomerulonephritis worldwide, and is one of the major causes of terminal renal failure in most industrialised countries. It is defined by the dominance of IgA mesangial deposits in immunofluorescence studies. Corticosteroid-sensitive nephrosis lipoides (minimal change disease) with IgA deposits and superimposed ...
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IgA nephropathy is the commonest form of glomerulonephritis worldwide, and is one of the major causes of terminal renal failure in most industrialised countries. It is defined by the dominance of IgA mesangial deposits in immunofluorescence studies. Corticosteroid-sensitive nephrosis lipoides (minimal change disease) with IgA deposits and superimposed ...
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Pathophysiology of IgA Nephropathy
Advances in Anatomic Pathology, 2017Immunoglobulin (Ig)A nephropathy is the most prevalent primary chronic glomerular disease in the world. Studies of molecular and cellular interactions involved in the pathogenesis of IgA nephropathy have revealed several inherent abnormalities in the production and subsequent handling of IgA1. In patients with this disease, altered glycan structures in
Turki, Al Hussain +3 more
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Pathogenesis of IgA nephropathy
Seminars in Nephrology, 2004In IgA nephropathy (IgAN), there is dysregulation of the IgA response to a wide range of antigens. The dysregulation promotes synthesis of polymeric IgA1 (pIgA1) with physicochemical characteristics that favor mesangial deposition, including altered O-glycosylation of the hinge region. This may be the synthesis of IgA in the systemic compartment, which
Barratt, J, Feehally, J, Smith, AC
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Inflammation in IgA nephropathy
Pediatric Nephrology, 2017Immunoglobulin A nephropathy (IgAN) is the most frequently occurring primary glomerulonephritis in Caucasian and Asian populations. Nonetheless, therapeutic recommendations are based on weak evidence, large controlled trials are scarce and, in particular, the additional value of immunosuppression beyond comprehensive supportive measures is not well ...
Thomas Rauen, Jürgen Floege
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The pathogenesis of IgA nephropathy
Current Opinion in Nephrology & Hypertension, 2011This review will analyze contemporary information concerning the possible pathogenetic mechanisms involved in IgA nephropathy, emphasizing studies in humans rather than experimental animals.Deposition of IgA in the glomeruli, the hallmark of IgA nephropathy, may be a quite common phenomenon.
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British Journal of Hospital Medicine, 2014
Ck, Cheung, S, Bashir, J, Barratt
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Ck, Cheung, S, Bashir, J, Barratt
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