Results 91 to 100 of about 220,566 (226)

The efficacy of rituximab in the treatment of IgA vasculitis nephritis

Clinical and Experimental Medicine (Testo stampato)
The utility of Rituximab (RTX) for IgA vasculitis nephritis (IgAVN) is not well established. Up to now, we analysed the largest samples of IgAVN patients treated by RTX with a total of 41 retrieved subjects up to December 29, 2023 in the present ...
Y. Xiong, Santiago Cuevas, Gaosi Xu, Honghong Zou   +3 more
semanticscholar   +1 more source

Exercise‐induced vasculitis with histological and genetic evidence of complement involvement

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Massimo Cugno, Paolo Calzari, Alessandra Di Benedetto, Francesca Laura Boggio, Chiara Moltrasio, Luigi Porcaro, Angelo Valerio Marzano   +6 more
wiley   +1 more source

Syncope as the Initial Presentation of Takayasu Arteritis in a 57‐Year‐Old Female: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Takayasu arteritis (TA) is a rare chronic granulomatous large‐vessel vasculitis predominantly affecting the aorta and its major branches, leading to stenosis, occlusion, or aneurysm formation. It typically presents in young women, though atypical cases can occur in older adults.
Chao Liu, Jiale Gan, Lili Feng, Yang Yang, Lianwei Dong, Jiabao Liu, Dingguo Zhang   +6 more
wiley   +1 more source

HLA Polymorphisms and Clinical Manifestations in IgA Vasculitis

International Journal of Molecular Sciences
Studies concerning the genetic background of IgA vasculitis (IgAV), a small-vessel vasculitis occurring predominantly in childhood, have confirmed that the HLA-DRB1 gene showed a strong association with disease susceptibility.
M. Held, K. Stingl Jankovic, M. Šestan, M. Šapina, N. Kifer, S. Srsen, M. Frković, A. Gagro, Zorana Grubic, M. Jelušić   +9 more
semanticscholar   +1 more source

Shifting From Systemic to Precision‐Targeted Complement Therapies: Opportunities and Hurdles

European Journal of Immunology, Volume 56, Issue 6, June 2026.
Complement therapeutics have expanded considerably, but systemic inhibitors remain limited by infection risks, breakthrough events, and loss of physiological functions. Emerging targeted approaches aim for organ‐, tissue‐, or cell‐specific modulation of complement activity, potentially offering greater precision while reducing treatment burden and ...
Marco Mannes, Wioleta M. Zelek, Leendert A. Trouw   +2 more
wiley   +1 more source

A specific diagnostic metabolome signature in adult IgA vasculitis

Metabolomics
IgA vasculitis diagnosis relies primarily on clinical features and is confirmed by pathological findings. To date, there is no reliable noninvasive diagnostic biomarker.
Alexandre Boissais, Hélène Blasco, Patrick Emond, A. Lefèvre, A. Bigot, Y. Ramdani, Nicole Ferreira Maldent, Denis Mulleman, É. Pillebout, François Maillot, A. Audemard-Verger   +10 more
semanticscholar   +1 more source

The profile and clinical outcomes of patients with renal involvement due to IgA vasculitis: is azathioprine a good option for treatment?

Advances in Rheumatology, 2019
Background The Henoch-Schönlein Purpura (HSP) orIgA vasculitis is the most common vasculitis of childhood and may occur with renal involvement, with hematuria and / or proteinuria, and may cause severe and non-reversible sequelae. Objectives To establish
Vânia Schinzel, Jade Dib Fernandez, Gleice Clemente, Melissa Mariti Fraga, Maria Cristina Andrade, Claudio Arnaldo Len, Maria Teresa Terreri   +6 more
doaj   +1 more source

The Role of Endothelin‐1 in Autoimmune Diseases: Mechanistic Insights and Therapeutic Targets

iNew Medicine, Volume 2, Issue 2, June 2026.
The Role of Endothelin‐1 in Autoimmune Diseases. NF‐κB: nuclear factor kappa‐B; MAPK: mitogen‐activated protein kinase; PI3K: phosphoinositide 3‐kinase; ROS: reactive oxygen species; CTGF: connective tissue growth factor; TGF‐β: transforming growth factor‐β.
Xun Gong, Zhenyu Wang, Suyin Yang, Kaige Gao, Xin Yang, Min Tang   +5 more
wiley   +1 more source

Food-induced IgA Vasculitis (Henoch-Schönlein Purpura)

European Journal of Case Reports in Internal Medicine, 2017
Immunoglobulin A (IgA) vasculitis is a rare entity in adults. It can be triggered by allergens such as drugs, food, or insect bites. We present a case of an adult male with a cutaneous IgA vasculitis of palpable purpura after eating canned sardines.
Javier Moreno Díaz, Ana Martinez Gonzalez, Rosa Eva Bautista Alonso, Jose Miguel García Bruñén, Gonzalo Acebes Repiso   +4 more
doaj   +1 more source

Origin of poorly galactosylated IgA1 other than mucosa: a viewpoint from a report on patient with IgA vasculitis

Renal Failure
Patients presenting monoclonal gammopathy of renal significance (MGRS) and IgA vasculitis collectively have rarely been reported. This study reports one patient with monoclonal IgA and λ, and with IgA positive-mesangial proliferative glomerulonephritis ...
Manxia Huang, Jian Cao, Yangpu Li, Hua Xu, Manliu Wang, Yihou Zheng, Mumin Shao, Youjia Zeng, Jicheng Lv   +8 more
doaj   +1 more source