A common theme in interaction of bacterial immunoglobulin-binding proteins with immunoglobulins illustrated in the equine system [PDF]
The M protein of Streptococcus equi subsp. equi known as fibrinogen-binding protein (FgBP) is a cell wall-associated protein with antiphagocytic activity that binds IgG. Recombinant versions of the seven equine IgG subclasses were used to investigate the
Abi-Rached+49 more
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ABSTRACT We present a neonate born to a mother with a known diagnosis of cutaneous polyarteritis nodosa (cPAN) who presented with acrocyanosis on the first day of life, which progressed to livedo reticularis and eventual digital necrosis and autoamputation.
Marin P. Melloy, Sheilagh Maguiness
wiley +1 more source
Tongue and tail necrosis in an atypical case of acute steroid responsive meningitis-arteritis in a dog [PDF]
Acute steroid responsive meningitis-arteritis (SRMA) is a common neurological disorder in young dogs. Typical clinical symptoms of the acute form of SRMA are neck pain, depression and fever. This case report describes a 1.5-year-old Pointer with uncommon
Chiers, Koen+6 more
core
Palpable Purpura in a Vietnamese Teenage Girl [PDF]
A 19-year-old Vietnamese female with no significant past medical history presented to the emergency department (ED) with fevers, sore throat, generalized myalgias, arthralgias, and a worsening lower extremity rash for the past two weeks.
Chiu, MSIII, Alan+2 more
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This graphical representation illustrates the multifaceted nature of the immune response in viral infections, demonstrating both its protective and potentially harmful aspects. While a properly regulated immune reaction facilitates viral clearance and promotes general recovery, an overly robust or misdirected response—exemplified by Type III or Type IV
Muhammed Cesim Karabulut+1 more
wiley +1 more source
Use of Plasmapheresis and Immunosuppressants to Treat Diffuse Alveolar Hemorrhage in a Patient with Granulomatosis with Polyangiitis. [PDF]
Granulomatosis with polyangiitis (GPA) is a systemic granulomatous inflammatory disease characterized by small-to-medium vessel vasculitis due to Central Anti-Neutrophil Cytoplasmic Antibody (C-ANCA).
Sattar, Yasar+4 more
core +1 more source
Malignancies Presenting With ANCA Positivity: Two Case Reports and Diagnostic Considerations
ABSTRACT Background ANCA‐associated vasculitides (AAV) are small‐vessel inflammatory disorders characterized by the presence of anti‐neutrophil cytoplasmic antibodies (ANCA), including those against proteinase 3 (PR3) and myeloperoxidase (MPO).
Min Zhao, Yue Lu, Ling Li
wiley +1 more source
Autoimmune hyperphosphatemic tumoral calcinosis in a patient with FGF23 autoantibodies [PDF]
Hyperphosphatemic familial tumoral calcinosis (HFTC)/hyperostosis-hyperphosphatemia syndrome (HHS) is an autosomal recessive disorder of ectopic calcification due to deficiency of or resistance to intact fibroblast growth factor 23 (iFGF23). Inactivating
Burbelo+14 more
core +1 more source
A 20-Year-Old Man with IgA Vasculitis following COVID-19 Vaccination
IgA vasculitis is a common type of vasculitis that is generally triggered by infectious causes. Vaccines have been reported as a trigger as well. Herein, we report a case of a young man who is previously healthy and who developed IgA vasculitis after the
Abdulaziz Alsubaie+4 more
doaj +1 more source
Laboratory Practices for the Detection and Characterization of Cryoglobulins and Cryofibrinogen
This study shows the importance of carrying out the search for both cryoproteins, cryoglobulins, and cryofibrinogen in cases of strong clinical suspicion of cryoproteinemia, despite their complex but not impossible detection. Use of correct procedures from the pre‐preanalytical phase up to reporting, of alternative methods such as immunotyping and the ...
Teresa Troiano+5 more
wiley +1 more source