Results 111 to 120 of about 185,240 (300)
Epileptic Disorders, EarlyView.Abstract The 15q11.2 microdeletion is a chromosomal condition associated with a broad epileptic phenotype. It is differentiated from Angelman syndrome, which is typically a larger maternal deletion in an overlapping area. We describe a patient with a 15q11.2 microdeletion that has clinical and EEG biomarker features similar to those seen in Angelman ...
Hok Leong Chin +2 more
wiley +1 more source
IgE-stimulated LAMP-1 translocation and early phase IL-6 production.
, 2018 Representative cytograms of (a) surface LAMP-1 expression (10 minute activation) and (c) intracellular IL-6 (90 minute activation) analyzed via flow cytometry.
Nicholas A. Pullen (5983337) +2 more
core +1 more source
KBG syndrome: A scoping review of electroclinical features of patients with epilepsy
Epileptic Disorders, EarlyView.Abstract Background and Objectives KBG syndrome is a rare autosomal developmental disorder caused by pathogenic variants of the ANKRD11 gene. This scoping review aimed to explore all current literature data regarding clinical and electroencephalographic features of patients with KBG syndrome and epilepsy. Materials and Methods We conducted a literature
Stefania Kalampokini +6 more
wiley +1 more source
, 2008 It is just forty years since the identification of immunoglobulin E (IgE) as the reagin responsible for allergen induced immediate hypersensitivity reactions.
Sihra, Bhupinder Singh
core +1 more source
Clinical trial barriers in neurostimulation for pediatric drug‐resistant epilepsy
Epileptic Disorders, EarlyView.Abstract Objective The NeuroPace responsive neurostimulation (RNS) System effectively treats focal drug‐resistant epilepsy (DRE) in adults but lacks pediatric regulatory approval. Despite effective off‐label pediatric use, systemic device‐trial challenges have impeded label expansion.
Mira C. Hasner +15 more
wiley +1 more source
Does age influence diagnostic outcomes in an adult cohort referred to a first‐seizure clinic?
Epilepsia, EarlyView.Abstract Objective The aging Danish population is associated with increasing morbidity and healthcare utilization. This study examines age‐related differences in resource utilization and diagnostic outcomes between older (65–95 years) and younger adults (18–64 years) evaluated for suspected epilepsy, including clinical management, diagnostic yield, and
Anne Line Lund Birkmose +3 more
wiley +1 more source
IgE and IgG B cell traffic in a low-dose Gal d1, 2, 3 allergy model
Медицинская иммунологияType I allergy is mediated by the formation of IgE antibodies to proteins secreted by nonreplicating microorganisms (plant pollen, house dust mites, etc.) that enter the mucous membranes in very low concentrations.
G. V. Fattakhova +7 more
doaj +1 more source
Appropriate selection for omalizumab treatment in patients with severe asthma?
European Clinical Respiratory Journal, 2017 Background: Omalizumab improves asthma control in patients with uncontrolled severe allergic asthma; however, appropriate patient selection is crucial. Information in this field is sparse.
Leo Nygaard +3 more
doaj +1 more source
Altered cortical synchronization in photosensitive idiopathic generalized epilepsy
Epilepsia, EarlyView.Abstract Objective To characterize cortical excitability and synchronization dynamics in patients with idiopathic generalized epilepsy (IGE) and photosensitivity by assessing steady‐state visual evoked potentials (SSVEPs) elicited by intermittent photic stimulation.
Alessandro Benedetto +5 more
wiley +1 more source
Epilepsia, EarlyView.Abstract Objective The polygenic risk score (PRS) for individuals with genetic generalized epilepsy (GGE) quantifies the common risk variants in genes identified in genome‐wide association studies. We hypothesized that the phenotype of GGE patients differs based on their GGE PRS. Methods We identified participants with highest (n = 59) versus lowest (n
Sophie von Brauchitsch +27 more
wiley +1 more source