Results 151 to 160 of about 488,312 (382)

Appropriate selection for omalizumab treatment in patients with severe asthma?

open access: yesEuropean Clinical Respiratory Journal, 2017
Background: Omalizumab improves asthma control in patients with uncontrolled severe allergic asthma; however, appropriate patient selection is crucial. Information in this field is sparse.
Leo Nygaard   +3 more
doaj   +1 more source

Allergens, germs and asthma [PDF]

open access: yes, 2015
Objective To explore asthma pathogenesis using data from upper and lower airways. Data Source English-language papers on human asthma and nasal polyp subjects from 1990 onwards.
Scadding, GK
core  

Ultra‐refractory epilepsy: The newly described entity

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Drug‐resistant epilepsy (DRE) is defined as the failure of two antiseizure medications (ASMs) to achieve complete seizure control, affecting approximately 30% of epilepsy patients. In some cases, additional ASMs and surgical approaches are also unsuccessful.
Jan Vinklárek   +13 more
wiley   +1 more source

The diagnostic value of semiology, EEG and MRI in new‐onset pediatric bilateral tonic–clonic seizures: A multimodal analysis

open access: yesEpilepsia Open, EarlyView.
Abstract Objective To assess the diagnostic contributions of semiology, Electroencephalography (EEG), brain magnetic resonance imaging (MRI), and longitudinal follow‐up both, individually and in combination in classifying seizure type (focal‐to‐bilateral tonic–clonic (FBTC) vs. generalized‐onset bilateral tonic–clonic (GBTC)) in children with new‐onset
Badiee Moussa   +7 more
wiley   +1 more source

Immune Sensitization in the Skin Is Enhanced by Antigen-Independent Effects of IgE [PDF]

open access: bronze, 2004
Paul Bryce   +5 more
openalex   +1 more source

Clock gene dysregulation in epilepsy: A systematic review

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Epileptic seizures show a rhythmic pattern, being more frequent at particular times of the day (e.g., only occurring during sleep), suggesting a role of the circadian rhythm. Clock genes regulate the circadian rhythm and might be involved in the pathophysiology of epilepsy.
Guilherme Fernandes‐Campos   +3 more
wiley   +1 more source

Component-Resolved in Vitro Diagnosis in Peach-Allergic Patients [PDF]

open access: yes, 2009
BACKGROUND: The in vitro diagnosis of pollen-related food allergy presents low specifi city and reproducibility with many conventional extracts. This can be improved using natural purifi ed allergens, recombinant purifi ed allergens, or both.
Antepara, I.   +8 more
core   +1 more source

Unveiling CLC as a Central Regulator of Allergic Rhinitis via the CLC‐CCL26/POSTN Axis: An Integrated Bioinformatics and Experimental Study

open access: yesFlavour and Fragrance Journal, EarlyView.
We unveil that CLC orchestrates the dual role of eosinophil recruitment via CCL26 and tissue remodelling via POSTN in allergic rhinitis, identifying it as a potential therapeutic target. ABSTRACT Allergic rhinitis (AR) is a chronic airway inflammation driven by a type 2 immune response, yet the molecular mechanisms underlying its persistence and tissue
Fanyu Yuan   +9 more
wiley   +1 more source

Insect‐Derived Bioactives for Glycemic Control and Gut Health: A Review

open access: yesFood Frontiers, EarlyView.
Insect‐derived bioactive compounds (e.g., peptides, polysaccharides) effectively regulate blood glucose through dual mechanisms: directly inhibiting carbohydrate‐digesting enzymes and glucose transporters, and indirectly modulating gut microbiota to enhance intestinal barrier integrity.
Chaoyi Lv   +5 more
wiley   +1 more source

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