Results 171 to 180 of about 102,976 (239)

Multi‐Omic Analysis of Scylla serrata Reveals the Allergen Landscape of Mud Crabs and Decapoda Species

Allergy, EarlyView.
Kelvin Fu‐Kiu Ao, Judy Kin Wing Ng, Cherie Tsz‐Yiu Law, Weixue Mu, Shanshan Li, Christine Yee Yan Wai, Man Fung Tang, Shannon Wing Ngor Au, Xiaoyu Liu, Ting Fan Leung, Qing Xiong, Stephen Kwok‐Wing Tsui   +11 more
wiley   +1 more source

Major Cat Allergen Fel d 4: Structure and Identification of a Cross‐Reactive IgE‐Epitope‐Containing Area

Allergy, EarlyView.
This study reports the three‐dimensional structure of an important cat allergen, Fel d 4, that shares high homology with Equ c 1 (i.e., major horse allergen) and Can f 6 (i.e., dog allergen). The C‐terminal region of the Fel d 4 contains a major IgE‐reactive epitope.
Nikolina Todorović, Daria Trifonova, Zicheng Liu, Mirela Curin, Laszlo Schooltink, Theo Sagmeister, Christoph Grininger, Renata Kiss, Nina Gottstein, Bernd Gesslbauer, Andreas Winkler, Tea Pavkov‐Keller, Alexander Karaulov, Rudolf Valenta, Walter Keller   +14 more
wiley   +1 more source

“Super‐Responders” to Dupilumab Treatment in Patients With Primary Diffuse Chronic Rhinosinusitis With Nasal Polyps

Allergy, EarlyView.
This study aimed to evaluate the feasibility of extending dupilumab dosing intervals in T2‐CRSwNP by assessing how many patients maintain disease control with once‐every‐12‐weeks (Q12W) dosing and comparing clinical characteristics of super‐responders and excellent responders. Tapering of dupilumab to Q12W appears feasible in super‐responding patients.
P. E. Vonk, J. J. Otten, H. B. E. Elzinga, R. J. L. van der Lans, G. F. J. P. Adriaensen, L. B. L. Benoist, D. R. Hoven, W. J. Fokkens, S. Reitsma, PolyREG Consortium, A.B. Rinia, I. Krebbers, I.J. Kleiss, M. E. Cornet   +13 more
wiley   +1 more source

Progressive Changes in Brain Morphology in People With Idiopathic Generalized Epilepsy. [PDF]

Neurology
Xiao F, Zhang Y, Wandschneider B, Binding LP, Giampiccolo D, Fleury M, Delazer L, Pimentel BC, Puntambekar I, Fukuma K, Caciagli L, Sander JW, Duncan JS, Zhou D, Koepp MJ.   +14 more
europepmc   +1 more source

Long‐Term Effect of Allergen Immunotherapy in Responder Local Allergic Rhinitis Patients: Symptom Control, and Prevention of Asthma and Allergic Sensitizations

Allergy, EarlyView.
LAR patients who respond to AIT during the first year and are treated for two more years continue improving (less symptoms and medication intake) during the following seven years. AIT prevents the onset of asthma and allergic sensitizations in responder LAR individuals during the seven years following discontinuation.
Almudena Testera‐Montes, Laura Zubiaga‐Fernandez, Carlos J. Aranda, Irene Garcia‐Esteban, Trinidad Ilda Gaitan‐Nievas, Dulce Sanchez‐Torralvo, Cristobalina Mayorga, Maria J. Torres, Ibon Eguiluz‐Gracia, Carmen Rondon   +9 more
wiley   +1 more source

A Straightforward Algorithm for Diagnosing Hymenoptera Venom Allergy and Identifying the Relevant Venom for Immunotherapy

Allergy, EarlyView.
Conventional tests, such as specific IgE (sIgE) or intradermal testing (IDT), are usually sufficient. Combining both tests increases sensitivity, while additional tests, like the basophil activation test (BAT), provide no further benefit for the majority of patients.
Lisa Arzt‐Gradwohl, Eva Schadelbauer, Urban Čerpes, Gudrun Pregartner, Sereina Annik Herzog, Elisabeth Jungwirth, Karin Laipold, Barbara Binder, Gunter J. Sturm   +8 more
wiley   +1 more source

Human KIT Antibody Briquilimab Diminishes Anaphylactic Responses in Mice Expressing Chimeric Human‐Mouse KIT

Allergy, EarlyView.
Hye‐Sook Kwon, Song Eun Lee, Ajay Sharma, Minyoung Youn, Charles A. Chang, Andrew Wells, Andrea R. Romo, Allison Ji, Sara Ratia, Sambidhan Kattel, Revati Nerkar, Karl Meneses, Cheryl Kwan, Mang Yu, Wendy W. Pang   +14 more
wiley   +1 more source

Decreased Severity of Oral Immunotherapy Induced Gastrointestinal Eosinophilic Reactions Following Revisions in Milk‐Treatment Protocol

Allergy, EarlyView.
A revised milk OIT protocol with lower daily allergen load and slower dose escalation reduced the severity and delayed onset of OIT‐induced gastrointestinal eosinophilic reactions (OITIGER). Elevated baseline absolute eosinophil count (AEC > 600/μL) was a consistent independent risk factor for OITIGER, while older age was protective.
Na'ama Epstein‐Rigbi, Matan Elkan, Yair Tzarfati, Michael B. Levy, Liat Nachshon, Yael Koren, Yitzhak Katz, Arnon Elizur, Michael R. Goldberg   +8 more
wiley   +1 more source

Molecular Biomarkers in IgE Immunoassays Used for Grass Pollen Allergy Diagnosis in European Clinical Settings. [PDF]

Int J Mol Sci
Gheorghita LM, Preda M, Marghidan CS, Lazar MI, Papacocea IR, Smolinska S, Popescu FD.   +6 more
europepmc   +1 more source