Results 11 to 20 of about 352,450 (307)
Assessment of sub-shelf melting parameterisations using the ocean–ice-sheet coupled model NEMO(v3.6)–Elmer/Ice(v8.3) [PDF]
Oceanic melting beneath ice shelves is the main driver of the current mass loss of the Antarctic ice sheet and is mostly parameterised in stand-alone ice-sheet modelling. Parameterisations are crude representations of reality, and their response to ocean
L. Favier +7 more
doaj +1 more source
Many contaminants of agricultural origin are released into rural environments, particularly at the soil surface. Their fate has been extensively investigated in repacked soils, but only few studies have addressed their transport in structurally preserved
Nico Hachgenei +11 more
doaj +1 more source
Anti-IgE therapy for IgE-mediated allergic diseases: from neutralizing IgE antibodies to eliminating IgE+ B cells [PDF]
Allergic diseases are inflammatory disorders that involve many types of cells and factors, including allergens, immunoglobulin (Ig)E, mast cells, basophils, cytokines and soluble mediators. Among them, IgE plays a vital role in the development of acute allergic reactions and chronic inflammatory allergic diseases, making its control particularly ...
Jiayun Hu +5 more
openaire +3 more sources
Quantification of different flow components in a high-altitude glacierized catchment (Dudh Koshi, Himalaya): some cryospheric-related issues [PDF]
In a context of climate change and water demand growth, understanding the origin of water flows in the Himalayas is a key issue for assessing the current and future water resource availability and planning the future uses of water in downstream regions.
L. Mimeau +7 more
doaj +1 more source
RÉSUMÉDans le contexte actuel de transition vers un monde plus chaud, le climat d’aujourd’hui n’est déjà plus celui d’hier. Parmi les multiples conséquences de ce réchauffement global, l’intensification des précipitations pourrait entraîner une ...
Guillaume Chagnaud +3 more
doaj +1 more source
Regulation of B cell fate by chronic activity of the IgE B cell receptor. [PDF]
IgE can trigger potent allergic responses, yet the mechanisms regulating IgE production are poorly understood. Here we reveal that IgE+ B cells are constrained by chronic activity of the IgE B cell receptor (BCR).
Allen, Christopher DC +6 more
core +1 more source
Temporal Changes in Total Serum Immunoglobulin E Levels in East German Children and the Effect of Potential Predictors [PDF]
Background: Elevated total serum immunoglobulin E (IgE) levels are a prominent feature of allergic and parasitic diseases. An epidemiologic study was conducted in East German children to describe trends in the development of total serum IgE levels and ...
Brüske, Irene +5 more
core +1 more source
The Surface Water and Ocean Topography (SWOT) mission is a next generation satellite mission expected to provide a 2 km-resolution observation of the sea surface height (SSH) on a two-dimensional swath. Processing SWOT data will be challenging because of
Sammy Metref +6 more
doaj +1 more source
This study aims to quantify the contribution of anthropogenic forcings on the retreat of the Argentière Glacier (European Alps). The glacier evolution is simulated over 1850–2014 following retrospective scenarios produced with the IPSL‐CM6‐LR climate ...
Léo Clauzel +6 more
doaj +1 more source
A comprehensive analysis of interleukin-4 receptor polymorphisms and their association with atopy and IgE regulation in childhood [PDF]
Background: The interleukin (IL) 4/IL13 pathway is involved in the regulation of IgE production associated with atopic diseases. Numerous polymorphisms have been identified in the coding region of the IL4 receptor alpha chain (IL4Ra) and previous ...
Carr, David +7 more
core +1 more source

