Results 31 to 40 of about 185,240 (300)
Sediment flows generate ground vibrations by exerting force fluctuations on the riverbed. Linking force fluctuations to properties of highly concentrated sediment flows, however, remains particularly challenging due to complexities arising from grain‐to ...
M. Piantini +5 more
doaj +1 more source
Prediction of an anti-IgE binding site on IgE [PDF]
A combination of computation techniques have been used to determine the binding site and amino acid residues on IgE that are critical for binding to a therapeutic anti-IgE. Homology modeling was used to model parts of IgE and of an antibody that binds to IgE.
J D, Wright, C, Lim
openaire +2 more sources
Genome-Wide Scan on Total Serum IgE Levels Identifies FCER1A as Novel Susceptibility Locus [PDF]
High levels of serum IgE are considered markers of parasite and helminth exposure. In addition, they are associated with allergic disorders, play a key role in anti-tumoral defence, and are crucial mediators of autoimmune diseases.
Wichmann, H. -Erich +127 more
core +1 more source
Triggering receptor expressed on myeloid cells 2 (TREM2) is known for its anti-inflammatory properties during the immune response, and influences negatively on TNF-α expression levels. Genetic epidemiology studies have identified polymorphisms located in
Vesna Gorenjak +6 more
doaj +1 more source
The rainfall regime of West Africa is highly variable over a large range of space and time scales. With rainfall agriculture being predominent in the region, the local population is extremely vulnerable to intraseasonal dry spells and multi-year droughts
Guillaume Chagnaud +4 more
doaj +1 more source
Environmental determinants of total IgE among school children living in the rural Tropics: importance of geohelminth infections and effect of anthelmintic treatment. [PDF]
BACKGROUND: The environmental factors that determine the elevated levels of polyclonal IgE observed in populations living in the Tropics are poorly understood but may include geohelminth infections.
Cooper Philip J +27 more
core +1 more source
Sensitivity of centennial mass loss projections of the Amundsen basin to the friction law [PDF]
Reliable projections of ice sheets' future contributions to sea-level rise require models that are able to accurately simulate grounding-line dynamics, starting from initial states consistent with observations.
J. Brondex +2 more
doaj +1 more source
ENU mouse mutagenesis: Generation of mouse mutants with aberrant plasma IgE levels [PDF]
peer reviewedBACKGROUND: The ENU Mouse Mutagenesis Project aims at a large-scale, systematic production of mouse mutants using the alkylating agent ethyl-nitrosourea (ENU).
Wolf, A. +17 more
core +1 more source
Allergic rhinitis in Samara: clinical and allergological aspects
The aim of the study was to study the dynamics of clinical and allergic characteristics of patients with allergic rhinitis (AR) in Samara over the past 5 years. Clinical and allergological examination was performed in 1526 patients from 2012 to 2018. For
N. N. Zhukova +2 more
doaj +1 more source
IgE, IgE Receptors and Anti-IgE Biologics: Protein Structures and Mechanisms of Action
The evolution of IgE in mammals added an extra layer of immune protection at body surfaces to provide a rapid and local response against antigens from the environment. The IgE immune response employs potent expulsive and inflammatory forces against local antigen provocation, at the risk of damaging host tissues and causing allergic disease.
J M, McDonnell +3 more
openaire +3 more sources

