IgE, IgE Receptors and Anti-IgE Biologics: Protein Structures and Mechanisms of Action
Annual Review of Immunology, 2023 The evolution of IgE in mammals added an extra layer of immune protection at body surfaces to provide a rapid and local response against antigens from the environment. The IgE immune response employs potent expulsive and inflammatory forces against local antigen provocation, at the risk of damaging host tissues and causing allergic disease.
J M, McDonnell +3 more
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Mimotope mapping as a complementary strategy to define allergen IgE-epitopes: peach Pru p 3 allergen as a model. [PDF]
, 2008 Lipid transfer proteins (LTPs) are the major allergens of Rosaceae fruits in the Mediterranean area. Pru p 3, the LTP and major allergen of peach, is a suitable model for studying food allergy and amino acid sequences related with its IgE-binding ...
Tordesillas Villuendas, Leticia +7 more
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Approaches to allergy detection using aptasensors [PDF]
, 2007 1. Immunoglobulins and IgE Antibodies are glycoprotein molecules which are produced by plasma cells in response to an immunogen (1). They belong to a class of spherical proteins called globulins and are hence known as immunoglobulins (Igs).
Mascini, Marco +4 more
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Geophysical Research Letters, 2023 Basal sliding of glaciers and ice sheets remains a source of uncertainty in simulating the long‐term evolution of ice masses. In particular, the response of ice flow to changes in driving stress depends strongly on the value of the exponent m in ...
A. Gilbert +3 more
doaj +1 more source
Soluble IgE receptors—Elements of the IgE network [PDF]
Immunology Letters, 2011 Soluble isoforms of three human IgE Fc receptors, namely FcεRI, FcεRII, and galectin-3, can be found in serum. These soluble IgE receptors are a diverse family of proteins unified by the characteristic of interacting with IgE in the extracellular matrix.
Barbara, Platzer +3 more
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Enu mouse mutagenesis: generation of mouse mutants with aberrant plasma IgE levels. [PDF]
, 2001 peer reviewedBACKGROUND: The ENU Mouse Mutagenesis Project aims at a large-scale, systematic production of mouse mutants using the alkylating agent ethyl-nitrosourea (ENU).
Wolf, A. +19 more
core +1 more source
Allergic rhinitis in Samara: clinical and allergological aspects
Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье, 2021 The aim of the study was to study the dynamics of clinical and allergic characteristics of patients with allergic rhinitis (AR) in Samara over the past 5 years. Clinical and allergological examination was performed in 1526 patients from 2012 to 2018. For
N. N. Zhukova +2 more
doaj +1 more source
IgE-associated enhancement of allergen presentation and T cell activation in atopic dermatitis
, 2004 Previous research has suggested that IgE-facilitated allergen presentation may play a key role in the pathogenesis of atopic dermatitis. This is the process by which allergen-specific IgE bound to Fcepsilon receptors on antigen presenting cells is able ...
Dawn. Cooper (7676549)
core +5 more sources
Temporal Changes in Total Serum Immunoglobulin E Levels in East German Children and the Effect of Potential Predictors [PDF]
, 2012 Background: Elevated total serum immunoglobulin E (IgE) levels are a prominent feature of allergic and parasitic diseases. An epidemiologic study was conducted in East German children to describe trends in the development of total serum IgE levels and ...
Wichmann, Heinz-Erich +11 more
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Effects of geohelminth infection and age on the associations between allergen-specific IgE, skin test reactivity and wheeze: a case-control study. [PDF]
, 2013 BACKGROUND: Most childhood asthma in poor populations in Latin America is not associated with aeroallergen sensitization, an observation that could be explained by the attenuation of atopy by chronic helminth infections or effects of age.
Oviedo, G +19 more
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