Results 51 to 60 of about 124,813 (135)
Interdisciplinary Medicine, EarlyView.Vaginal microbiota‐derived secretory factors enhance the regenerative capacity of human endometrial stem cells by upregulating VCAM1 and activating PI3K/Akt signaling. This microbiota–stem cell crosstalk promotes self‐renewal, migration, multilineage differentiation, and metabolic reprogramming in vitro and in vivo, establishing a novel microbiota ...
Soo‐Rim Kim +6 more
wiley +1 more source
Presence of IGF-1 receptor and insulin receptor (IGF-1R/INSR) hybrid in corneal epithelium.
, 2012 (A) Reciprocal immunoprecipitation (IP) of IGF-1 receptor and insulin receptor in the hTCEpi cell line. Whole cell lysates were subjected to IP with antibodies against either the IGF-1 receptor (IGF-1R) β-subunit (CST#3027) or the insulin receptor (INSR)
Danielle M. Robertson (145361) +2 more
core +1 more source
, 2021 AimInsulin-like growth factor-1 receptor (IGF-1R) is one of the main members of the tyrosine protein kinase receptor family. This receptor binds insulin-like growth factor-1 (IGF-1) with a high affinity. IGF-1 is a member of a family of proteins involved
Yinqi Zhang (11652286) +10 more
core +1 more source
Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives
JSFA reports, EarlyView.Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz +10 more
wiley +1 more source
, 2021 AimInsulin-like growth factor-1 receptor (IGF-1R) is one of the main members of the tyrosine protein kinase receptor family. This receptor binds insulin-like growth factor-1 (IGF-1) with a high affinity. IGF-1 is a member of a family of proteins involved
Yinqi Zhang (11652286) +10 more
core +1 more source
IGF-1R : studies on the expression and role in transformation
, 2009 Transformation is a complex nonlinear multistep process during which normal cell becomes cancerous. Main characteristics of transformed cells include uncontrolled growth, invasion and metastasis.
Natalia Natalishvili (19525831)
core +1 more source
Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment
Med Research, EarlyView.An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu +9 more
wiley +1 more source
, 2021 AimInsulin-like growth factor-1 receptor (IGF-1R) is one of the main members of the tyrosine protein kinase receptor family. This receptor binds insulin-like growth factor-1 (IGF-1) with a high affinity. IGF-1 is a member of a family of proteins involved
Yinqi Zhang (11652286) +10 more
core +1 more source
Journal of Lipid Research, 2005 Oxidized low density lipoprotein (OxLDL) has multiple proatherogenic effects, including induction of apoptosis. We have recently shown that OxLDL markedly downregulates insulin-like growth factor-1 receptor (IGF-1R) in human aortic smooth muscle cells ...
Yusuke Higashi +7 more
doaj +1 more source
IGF-1R targeting in cancer – does sub-cellular localization matter?
Journal of Experimental & Clinical Cancer Research, 2023 The insulin-like growth factor receptor (IGF-1R) was among the most intensively pursued kinase targets in oncology. However, even after a slew of small-molecule and antibody therapeutics reached clinical trials for a range of solid tumors, the initial ...
Upendra K. Soni +2 more
doaj +1 more source