Cutting edge strategies for diabetic wound care: Nanotechnology, bioengineering, and beyond
BMEMat, EarlyView.Graphical abstract illustrates the challenges in diabetic wound healing, covering pathophysiology, formulation hurdles, and emerging therapeutic strategies. It highlights the role of hyperglycemia, formulation complexities, and advanced technologies like bioprinting and AI in improving diabetic wound management. Abstract Diabetic wounds affect millions
Usama Ahmad +8 more
wiley +1 more source
Verapamil Prevents Decline of IGF-I in Subjects With Type 1 Diabetes and Promotes β-Cell IGF-I Signaling. [PDF]
Diabetes, 2023 Xu G +5 more
europepmc +1 more source
Improvement of EPO Transgene Detection From Polymeric Dried Blood Spots for Antidoping Application
Drug Testing and Analysis, EarlyView.This article presents an optimized protocol for gene doping detection. Starting from one spot DBS (20 μL), concentrated DNA was obtained and real‐time PCR parameters were adjusted for increased detection. Robust detection of 5000 copies/mL of transgene was validated for polymeric device TASSO M‐20.
Alexandre Marchand +2 more
wiley +1 more source
Insulin and IGF-I stimulate phosphorylation of their respective receptors in intact neuronal and glial cells in primary culture [PDF]
, 1989 Joshua Shemer +5 more
openalex +1 more source
Pss knockdown in the midgut causes growth retardation in Drosophila similar to that in human LMHD
Developmental Dynamics, EarlyView.Abstract Background Phosphatidylserine synthase (PSS), localized in the mitochondrial membrane, synthesizes phosphatidylserine. In humans, mutations in Pss lead to Lenz–Majewski hyperostotic dwarfism, a disorder affecting growth and development. The effects of Pss mutations on the growth of Drosophila melanogaster are not fully known. Hence, this study
Kwan‐Young Kim +4 more
wiley +1 more source
Estudo quantitativo das células granulares adenohipofisárias associadas à produção do hormônio de crescimento e avaliação do perfil bioquímico do IGF-I em cães Golden Retriever com Distrofia Muscular (GRMD) [PDF]
, 2005 Ana Rita de Lima
openalex +1 more source
The cloning, characterisation and engineering of an IGF-I-BINDING single chain Fv [PDF]
, 2004 This thesis describes the construction and characterisation of an insulin-like growth factor (IGF-I)-binding single chain Fv (scFv) and the utilisation of this scFv as a model protein for the study of the application of DNA shuffling and ribosome display
Roberts, Anthony Simon
core +1 more source
International Journal of Eating Disorders, EarlyView.ABSTRACT Objective Anorexia nervosa (AN) is a severe eating disorder associated with extreme weight loss, hyperactivity, and amenorrhea. Neuroimaging studies revealed brain atrophy and disruption of white matter integrity in the corpus callosum (CC) of patients with AN. However, the underlying pathophysiological mechanisms remain unclear.
Stephan Lang +9 more
wiley +1 more source
Tecnociencia Chihuahua, 2020 La adición de IGF-I a los medios de fertilización in vitro y cultivo de embriones ha sido propuesta como una forma de imitar las señales maternas de la gestación temprana en el útero. El objetivo del presente estudio fue evaluar la adición
Octavio Martínez-Guerrero +2 more
doaj
Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues
ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang +7 more
wiley +1 more source