Results 121 to 130 of about 87,101 (260)
Vesiculin derived from IGF-II drives increased islet cell mass in a mouse model of pre-diabetes. [PDF]
Islets, 2022 Lee KL +7 more
europepmc +1 more source
Efficacy, safety and cost‐effectiveness of CAR‐T therapy
British Journal of Clinical Pharmacology, EarlyView.CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher +7 more
wiley +1 more source
Communications BiologyThe insulin-like growth factor II/mannose 6-phosphate (IGF-II/M6P) receptor is a multifunctional glycoprotein not only play roles in IGF-II degradation and pro-TGFβ activation but binding to and transport M6P-bearing lysosomal enzymes from the trans ...
Susumu Nishida +4 more
doaj +1 more source
Alteration of Metabolic Conditions Impacts the Regulation of IGF-II/H19 Imprinting Status in Prostate Cancer. [PDF]
Cancers (Basel), 2021 Kingshott G +15 more
europepmc +1 more source
Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges
BMEMat, EarlyView.This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma +8 more
wiley +1 more source
Quercetin Modulates IGF-I and IGF-II Levels After Eccentric Exercise-Induced Muscle-Damage: A Placebo-Controlled Study. [PDF]
Front Endocrinol (Lausanne), 2021 Sgrò P +9 more
europepmc +1 more source
Harnessing bacterial extracellular vesicles for bone and cartilage organoids
BMEMat, EarlyView.This review presents bacterial extracellular vesicles (BEVs) as programmable bioactive regulators for bone and cartilage organoids by delivering functional cargos that modulate skeletal remodeling. It highlights key engineering strategies and future directions to advance next‐generation organoid models for bone aging related diseases.
Han Liu +8 more
wiley +1 more source
Decolorization of Disperse Dyes in Textile Polyester Recycling Using Activated Carbon
Chemie Ingenieur Technik, EarlyView.Decolorization of disperse dyes from disodium terephthalate solutions is examined using two activated carbons with varying pore structures and surface properties. The potential impact of pore size distribution and surface charge on the adsorption process is assessed to support optimized adsorbent selection.
Charlotte Lücking +2 more
wiley +1 more source
Developmental Dynamics, EarlyView.Abstract Background The zebrafish heart regenerates upon injury. During injury response, fibroblasts and endothelial cells accumulate at the site of damage, and cardiomyocyte cell cycle reentry allows cardiac muscle regrowth. It is relevant to understand how the different cell types communicate with each other to coordinate regeneration.
João A. S. Carvalho +6 more
wiley +1 more source
Revista Colombiana de Química, 2010 Las metaloproteinasas 2 y 9 (MMP-2 y MMP-9) y el inhibidor-1 de MMP (TIMP-1) podrían contribuir a la regulación del comportamiento invasivo de las células trofoblásticas, efecto que podría ser mediado por el factor de crecimiento similar a la insulina ...
Martha Pinzón +5 more
doaj