Results 161 to 170 of about 1,114,806 (299)

Evolving Platinum‐Copper Nanostructures for Enhanced Photothermal Therapy and Controlled Copper Release in Cancer Therapy

Advanced Functional Materials, EarlyView.
Platinum‐Copper bimetallic nanoparticles may evolve depending on their synthesis under tumor microenvironment conditions and play a dual role as chemotherapeutic agents after releasing Cu ions and as near infrared photothermal agents with the Pt‐rich remaining frames.
Jose I. Garcia‐Peiro, María Sancho‐Albero, Silvia Miguel, Andrea Mosseri, Felipe Hornos, Rafael Contreras‐Montoya, Jose L. Hueso, Jesus Santamaria   +7 more
wiley   +1 more source

Endocytic Programming via Porous Silicon Nanoparticles Enhances TLR4 Nanoagonist Potency for Macrophage‐Mediated Immunotherapy

Advanced Functional Materials, EarlyView.
Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang, Huiying Li, Shuodan Huang, Linxuan Zhang, Yan Gao, Ruoran Wang, Xiaoyu Wang, Hélder A. Santos, Zhenyu Yin, Bing Xia   +9 more
wiley   +1 more source

Quantification of endogenous and therapeutic IgG crossing the kidney barrier from bloodstream to urine [PDF]

Barbara Eicher, Christoph Esslinger, Matthias Hillenbrand   +2 more
openalex   +1 more source

Suppression of allo-human leucocyte antigen (HLA) antibodies secreted by B memory cellsin vitro: intravenous immunoglobulin (IVIg) versusa monoclonal anti-HLA-E IgG that mimics HLA-I reactivities of IVIg [PDF]

, 2014
Dong Zhu, Mepur H. Ravindranath, Paul I. Terasaki, Tôru Miyazaki, Trung H.M. Pham, Vadim Jucaud   +5 more
openalex   +1 more source

Cholesterol in mRNA‐Lipid Nanoparticles can be Replaced with the Synthetic Mycobacterial Monomycoloyl Glycerol Analogue MMG‐1

Advanced Functional Materials, EarlyView.
This study demonstrates that cholesterol in messenger RNA‐lipid nanoparticles (mRNA‐LNPs) can be completely replaced with an immunopotentiating lipid, i.e., a synthetic analogue of the C‐type lectin receptor agonist monomycoloyl glycerol (MMG‐1), without compromising physicochemical properties, in vivo transfection efficiency, and immunogenicity of the
Abhijeet G. Lokras, Saahil S. Baghel, Rune F. Jensen, Aneesh Thakur, Henrik Franzyk, Oskar Thofte, Marco Herrera‐Barrera, Madeleine Landry, Melike Ongun, Ahmad Tami, Marlene P. Thanthrige, Eva Callens, Corinne Beinat, Thomas Rades, Søren R. Paludan, Kristian Riesbeck, Ida Rosenkrands, Dennis Christensen, Gabriel K. Pedersen, Camilla Foged   +19 more
wiley   +1 more source

Bronchiectasis, Low IgG Levels and Lack of Vaccination are Risk Factors for Covid-19 Hospitalization in X-linked Agammaglobulinemia – A Retrospective Multicenter Study [PDF]

Stenlander, Caroline, Lindahl Hannes, Wahren-Borgström, Emelie, Geier, Christoph B., Sediva Anna, Fevang, Børre, Milito, Cinzia, Varandas, Cláudia, Roca-Oporto, Cristina, Pulvirenti Federica, Hodl, Isabel, Malkusova, Ivana, Rivière, Jacques G., Litzman Jiri, Walter, Jolan E., Hanitsch, Leif G., Neth Olaf, Králíčková Pavlína, Miller, Rahim, Shaffren, Serena, Silva, Susana L., Katzenstein, Terese, Martelius Timi, Steiner, Urs C., Smith, C. I. Edvard, Warnatz, Klaus, Bergman, Peter   +26 more
openalex   +1 more source

FeDSNP‐Pa Nanoassemblies: A Triple‐Action Therapeutic Strategy Targeting Oxidative Stress, Inflammation, and Pyroptosis for Retinal Ganglion Cell Protection in Glaucoma

Advanced Functional Materials, EarlyView.
FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu, Xue Li, Tong Wu, Dan Ji, Yugang Bai, Xuezhi Zhou   +5 more
wiley   +1 more source

Generation of Increased Numbers of HLA-DRhigh IgG+ Plasma Cells in the Peripheral Blood of Patients with Bullous Pemphigoid: NC16a-Specific Cells Belong to the Short-Lived Plasma Blast Population [PDF]

, 2010
Susanne László, Susanne Neumann, Michael Hertl, Nicolas Hunzelmann   +3 more
openalex   +1 more source

Quantitative Estimation of IgM and IgG Antibodies Against SARS-CoV-2 v1 [PDF]

, 2020
Abhinay Gontu, Sreenidhi Srinivasan, Meera Surendran Nair, Scott E. Lindner, Allen M. Minns, Randall M. Rossi, Suresh V. Kuchipudi, Vivek Kapur   +7 more
openalex   +1 more source

Cell‐Delivering Injectable Hydrogels with Tunable Microporous Structures Improve Therapeutic Efficacy for Volumetric Muscle Loss

Advanced Functional Materials, EarlyView.
The study presents an injectable hydrogel with tunable microporosity to improve mesenchymal stem cell delivery for volumetric muscle loss treatment. Mesenchymal stem cells encapsulated in porous hydrogels significantly promote the spreading, proliferation, and cytokine secretion of mesenchymal stem cells.
Hana Yasue, Tetsushi Taguchi, Taka‐Aki Asoh, Akihiro Nishiguchi   +3 more
wiley   +1 more source