Results 221 to 230 of about 1,416,853 (336)

Tissue Engineered Human Elastic Cartilage From Primary Auricular Chondrocytes for Ear Reconstruction

Advanced Functional Materials, EarlyView.
Despite over three decades of research, no tissue‐engineered solution for auricular reconstruction in microtia patients has reached clinical translation. The key challenge lies in generating functional elastic cartilage ex vivo. Here, we integrate synergistic cell‐biomaterial strategies to engineer auricular grafts with mechanical and histological ...
Philipp Fisch, Sandra Kessler, Simone Ponta, Anna Puiggalí‐Jou, Guoliang Lyu, Killian Flégeau, Anastasiya Martyts, Florian Roth, David Fercher, Filippo M. Rijli, Daniel Simmen, Eva Novoa Olivares, Thomas Linder, Marcy Zenobi‐Wong   +13 more
wiley   +1 more source

Serum PLA2R-IgG4/PLA2R-IgG ratio dynamics reveal pathogenic autoantibody subclass switch during progression of PLA2R-associated membranous nephropathy. [PDF]

Ann Med
Zhong Y, Liu Y, Zhou D, Tian J, Chen D, Liang D, Liang S, Zhen T, Zhu X, Huang B, Zeng C.   +10 more
europepmc   +1 more source

First site-specific conjugation method for native goat IgG antibodies via glycan remodeling at the conserved Fc region

Michael E. Dolan, Amissi Sadiki, Lei Wang, Yan Wang, Christopher Barton, Sheldon F. Oppenheim, Zhaohui Sunny Zhou   +6 more
openalex   +1 more source

Membrane Vesicles from Lacticaseibacillus Casei BL23 Exhibit Antimicrobial Activity Against Escherichia coli and Immunostimulatory Effects on Human Peripheral Blood Mononuclear Cells

Advanced Healthcare Materials, EarlyView.
Membrane vesicles derived from the probiotic Lacticaseibacillus casei BL23 demonstrate antimicrobial properties against Escherichia coli and a potential biological effect in improving the overall survival of C. elegans infected with Pseudomonas aeruginosa. These vesicles stimulated immune responses in primary cells without causing toxicity. Our results
Cecilia L. D'Antoni, Leila Pourtalebi Jahromi, Lorenzo Sana, Ana Paula Domínguez Rubio, Maja Dorfner, Jennifer Munkert, Heike Danzer, Philipp Arnold, Mikhail Lebedev, Esther Zanin, Oscar E. Pérez, Gregor Fuhrmann   +11 more
wiley   +1 more source

Impaired systemic antibody response against gut microbiota pathobionts in critical illness and susceptibility to nosocomial infections. [PDF]

Intensive Care Med Exp
Cho NA, Schlechte J, Yu IL, Bains I, Fahlman T, Mackenzie C, McDonald B.   +6 more
europepmc   +1 more source

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

Extending ImmunoSpot^® Assays' Sensitivity for Detecting Rare Antigen-Specific B Cells to One in a Million-And Possibly Lower. [PDF]

Vaccines (Basel)
Kirchenbaum GA, Becza N, Yao L, Karulin AY, Lehmann PV.   +4 more
europepmc   +1 more source

Detection of IgA and low-avidity IgG antibodies for the diagnosis of recent active toxoplasmosis [PDF]

, 1997
José Gutiérrez Fernández, Marí­a José Rodrí­guez, G Piédrola, María del Carmen Maroto   +3 more
openalex   +1 more source

Multiscale Hybrid Surface Topographies Orchestrate Immune Regulation, Antibacterial Defense, and Tissue Regeneration

Advanced Healthcare Materials, EarlyView.
Hybrid wrinkled topographies coordinate immune, tissue, and bacterial interactions. The surfaces promote osteointegration, tune macrophage polarization, and inhibit biofilm formation, highlighting a multifunctional strategy for next‐generation implant design.
Mohammad Asadi Tokmedash, Jacob Robins, J. Scott VanEpps, Minji Kim, Jouha Min   +4 more
wiley   +1 more source

Astrocyte-intrinsic signaling of chitinase-like protein CHI3L1 drives inflammation and amplifies demyelination in neuromyelitis optica. [PDF]

J Clin Invest
Xu H, Jiang W, Xu L, Li H, Yang X, Zhu F, He P, Song Y, Li Y, Huang YA, Qiu W, Tang C.   +11 more
europepmc   +1 more source