Results 241 to 250 of about 1,114,806 (299)

Characterization of the humoral immune response in Plasmodium falciparum malaria. III. Factors influencing the coexpression of antibody isotypes (IgM and IgG-1 to 4).

, 1986
Mats Wahlgren, Hedvig Perlmann, Kathryn Berzins, Anders Björkman, Å. Larsson, Inger Ljungström, M E Patarroy, Peter Perlmann   +7 more
openalex   +1 more source

Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization

Advanced Healthcare Materials, EarlyView.
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng 
Molood Behbahanipour, Carla Goldin, Cecilia Arahi Prato, Ana Luz Paletta, Oriol Bárcenas, Susanna Navarro, Jordi Pujols, Daniel H. Murgida, María Virginia Tribulatti, Sebastián Esperante, Damian Alvarez‐Paggi, Salvador Ventura   +11 more
wiley   +1 more source

eNAMPT/TLR4 signaling drives PAH cellular phenotypic switching and lung vascular remodeling. [PDF]

Cell Commun Signal
Ahmed M, Kee SL, Zaghloul N, Casanova NG, Rodriguez M, Kempf CL, Camp SM, Song JH, Sammani S, Gupta A, Bryant AJ, Ooi A, Desai AA, Makino A, Yuan JX, Benos PV, Dai Z, Garcia JGN.   +17 more
europepmc   +1 more source

Synthetic Cell‐Based Tissues for Bottom‐Up Assembly of Artificial Lymphatic Organs

Advanced Healthcare Materials, EarlyView.
Synthetic cells have emerged as a novel biomimetic approach for fundamental research and therapeutic interventions. T cell activating synthetic cells are able to form 3D tissue‐like structures by self‐assembly into lymphatic bottom‐up tissues (lymphBUT) with tunable biochemical and biomechanical functionalities as well as metabolic activity are ...
Anna Burgstaller, Tamara Nink, Niklas Walter, Erick Angel Lopez Lopez, Hsin‐Fang Chang, Oskar Staufer   +5 more
wiley   +1 more source

A Multicentric Clinical Study to Evaluate Pharmacokinetics, Efficacy, and Safety of Immune Globulin Subcutaneous 20% Weekly/Biweekly Dosing in Treatment-Experienced Patients and Loading/Weekly Maintenance Dosing in Treatment-Naïve Patients with Primary Immunodeficiency. [PDF]

J Clin Immunol
Lumry WR, Palumbo M, Hsu C, Hussain I, McNeil D, Bridges T, Wedner HJ, Scarupa M, Mondou E, Nanaware-Kharade N, Hanna K, Coll MQ, Oliveras J.   +12 more
europepmc   +1 more source

Analysis of Pre-existing IgG and IgM Antibodies against Polyethylene Glycol (PEG) in the General Population.

Analytical Chemistry, 2016
Qi Yang, T. Jacobs, Justin D. McCallen, D. Moore, J. Huckaby, Jasmine Edelstein, S. Lai   +6 more
semanticscholar   +1 more source

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

Therapeutic IgG- and IgM-specific proteases disarm the acetylcholine receptor autoantibodies that drive myasthenia gravis pathology. [PDF]

Proc Natl Acad Sci U S A
Bayer AC, Sanmarco LM, Pellerin A, Masi G, Plasencia A, Anderson JM, Nowak RJ, Damato V, Massacesi L, Pham MC, Khani-Habibabadi F, Vital H, Higginson-Scott N, Otipoby KL, Xing Y, Mascanfroni ID, O'Connor KC.   +16 more
europepmc   +1 more source

Fibrillar Bundles as Fibrous Filler Materials for Attaining Cell Anisotropy in Bioprinting

Advanced Healthcare Materials, EarlyView.
Fibrillar bundles are introduced as a bioprintable additive that enables robust and scalable cellular alignment within 3D constructs through flow‐induced orientation during extrusion. These fibers support strong cell adhesion and polarization across various cell types and significantly enhance myotube alignment in Gelatine‐Methacryloyl (GelMA ...
Sven Heilig, Zan Lamberger, Lys Sprenger, Vivien Priebe, Camilla Mussoni, Denitsa Docheva, Kristina Andelovic, Jürgen Groll, Sahar Salehi, Gregor Lang, Matthias Ryma   +10 more
wiley   +1 more source

Developing accessible and affordable tests to support mpox immunosurveillance and vaccine studies. [PDF]

Emerg Microbes Infect
Faustini SE, Jones S, Green CA, Otter AD, Richter AG, Heaney JLJ.   +5 more
europepmc   +1 more source