Results 251 to 260 of about 1,416,853 (336)

Synthetic mucus biomaterials enable localized therapeutic antibody delivery in inflammatory bowel disease. [PDF]

APL Bioeng
Yeruva T, Yang S, Kaluzienski M, Louisthelmy R, Doski S, Maisel K, Duncan GA.   +6 more
europepmc   +1 more source

Enhancing Magnetic Hyperthermia at the Cell Membrane by Anchoring 92R‐Functionalized Magnetic Nanoparticles to Low‐Endocytic CCR9 Surface Receptors

Advanced Healthcare Materials, EarlyView.
We present a strategy to enhance magnetic hyperthermia therapy by modulating nanoparticle–cell interactions. Antibody‐functionalized magnetic nanoparticles targeting the low‐internalizing CCR9 receptor enable spatially controlled membrane anchoring, reducing aggregation and maximizing heat generation under alternating magnetic fields.
David Egea‐Benavente, Isabel Corraliza‐Gorjón, Thomas S. van Zanten, María del Puerto Morales, Leonor Kremer, Domingo F. Barber   +5 more
wiley   +1 more source

Platelet Lysate–Enriched Human Induced Pluripotent Stem Cell–Derived Chondrocyte Sheets for Bone Defect Repair via Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. Abstract Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.
Yiwei Chen, Jiali Lin, Jiapeng Li, Yiwei Hu, Jiansen Su, Yu Miao, Lanlan Wang, Qian Tang, Changqing Zhang, Junhui Yin   +9 more
wiley   +1 more source

A 3D Bioprinted Spheroid‐Laden dECM‐Enriched Osteosarcoma Model for Enhanced Drug Testing and Therapeutic Discovery

Advanced Healthcare Materials, EarlyView.
A 3D biomimetic OS model was developed by bioprinting an OS‐cell‐derived dECM‐enriched bioink with OS spheroids incorporated. The model showed upregulation of known OS prognostic markers and increased resistance to doxorubicin, compared to 2D cultures and scaffold‐free spheroids, making this a more clinically relevant platform for drug discovery ...
Margarida F. Domingues, Maria Catarina Carreira, Mafalda S. Santos, Daniela Pacheco, Frederico Castelo Ferreira, Paola Sanjuan‐Alberte, João Carlos Silva   +6 more
wiley   +1 more source

Human FcRL5 is an Fc receptor that simultaneously engages two IgGs. [PDF]

Sci Adv
Chen S, Li S, Zhang Z, Xiao J.
europepmc   +1 more source

Divergent IgE to IgG hypermutation is associated with allergic hypothermia in mice [PDF]

Christopher C. Udoye, Christina N. Rau, Ann‐Katrin Clauder, Timo Lindemann, Larissa N. Almeida, Justin Goetzie, Pia Witt, Sahar Mehrabhani, Swayanka Biswas, Daniel Seiler, Marie Kleingarn, Marc Ehlers, Mats Ohlin, Kathrin Kalies, Anke Fähnrich, Fred D. Finkelman, Rudolf A. Manz   +16 more
openalex   +1 more source

Fibrillar Bundles as Fibrous Filler Materials for Attaining Cell Anisotropy in Bioprinting

Advanced Healthcare Materials, EarlyView.
Fibrillar bundles are introduced as a bioprintable additive that enables robust and scalable cellular alignment within 3D constructs through flow‐induced orientation during extrusion. These fibers support strong cell adhesion and polarization across various cell types and significantly enhance myotube alignment in Gelatine‐Methacryloyl (GelMA ...
Sven Heilig, Zan Lamberger, Lys Sprenger, Vivien Priebe, Camilla Mussoni, Denitsa Docheva, Kristina Andelovic, Jürgen Groll, Sahar Salehi, Gregor Lang, Matthias Ryma   +10 more
wiley   +1 more source

Quantification of the IgG antibody response half-life for hybrid immunity to SARS-CoV-2. [PDF]

BMC Med
Bongiovanni F, Conway E, Smith L, Cumming J, Mazhari R, Kiernan-Walker N, Eriksson EM, McVernon J, Mueller I.   +8 more
europepmc   +1 more source