Results 321 to 330 of about 1,067,036 (373)

Gut microbiota modulate immune responses to orally and parenterally administered rotavirus in mice. [PDF]

open access: yesNPJ Vaccines
Shi Z   +13 more
europepmc   +1 more source

Transcriptomic Profiling Unveils EDN3+ Meningeal Fibroblasts as Key Players in Sturge‐Weber Syndrome Pathogenesis

open access: yesAdvanced Science, EarlyView.
Sturge‐Weber syndrome (SWS) is characterized by leptomeningeal vascular malformations, leading to seizures and stroke. Analysis of 119 446 brain cells from SWS patients uncovered distinct cell heterogeneity and identified an EDN3⁺ meningeal fibroblast cluster, with WNT5A emerging as a potential key driver of SWS progression and a promising therapeutic ...
Daosheng Ai   +14 more
wiley   +1 more source

Artesunate Inhibits Neointimal Hyperplasia by Promoting IRF4 Associated Macrophage Polarization

open access: yesAdvanced Science, EarlyView.
This study shows that macrophage interferon regulatory factor 4 (IRF4) improved arterial injury‐induced neointimal hyperplasia by promoting of M2 polarization via up‐regulating krüppel‐like factor 4 (KLF4) in rodent and nonhuman primate models. Notably, artesunate is identified as a potent inducer of IRF4 in macrophages, and proposed as a promising ...
Jinlin Miao   +15 more
wiley   +1 more source

Discrepancy in SARS-CoV-2 Infection Status Among PCR, Serological, and Cellular Immunity Assays of Nucleocapsids: A Historical Cohort Study. [PDF]

open access: yesVaccines (Basel)
Uchiyama T   +13 more
europepmc   +1 more source

Nanotherapy for Neural Retinal Regeneration

open access: yesAdvanced Science, EarlyView.
Nanotechnology enhances ophthalmic treatments by improving drug delivery and regenerating ocular tissues, combating vision loss from retinal diseases through innovative nano‐systems. This review outlines ocular anatomy, pathology, immune microenvironment, and barriers, detailing nanocarrier characteristics, classification, and preparation methods, and ...
Chuyao Yu   +11 more
wiley   +1 more source

Prolonged Zika Virus NS1 Protein Circulation in Patient Sera Impacts Clinical Outcome Before the Rise of a Specific IgM Response. [PDF]

open access: yesJ Med Virol
Tamietti C   +13 more
europepmc   +1 more source

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