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ANCA and IgG Subclasses [PDF]

open access: possible, 1993
We studied IgG subclass distribution of ANCA in 247 patients with ELISA. We used monoclonal subclass specific antibodies and purified MPO and proteinase 3 as antigen. We found that IgG1 and IgG4 yield high values in both groups. We also found that high IgG2 titers were rare among the anti-proteinase 3 positive, while it was common among anti-MPO sera ...
Mårten Segelmark, Jörgen Wieslander
openaire   +2 more sources

Oligoclonal IgG in tears [PDF]

open access: possibleNeurology, 1987
We examined tears from patients with MS and systemic or eye diseases, and normal controls. Tears were isoelectrofocused on agarose gel, silver-stained, and immunofixated for IgG. In the cathodal portion of the gel (pH greater than or equal to 8.3), oligoclonal bands were detected in 14 of 21 (67%) MS tear samples.
Cynthia Johnson   +2 more
openaire   +2 more sources
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Quantitation of human total IgG, kappa IgG and lambda IgG in serum using monoclonal antibodies

Journal of Immunological Methods, 1980
Monoclonal antibodies to human IgG have been applied, in parallel with polyclonal antisera, to the routine quantitation of human IgG. Two monoclonal antibodies directed against spatially distinct epitopes have been used in combination to form insoluble complexes exhibiting turbidity.
W.G. Reeves   +3 more
openaire   +2 more sources

IgG SUBCLASS DEFICIENCIES

Annual Review of Medicine, 1987
IgG subclasses represent distinct immunoglobulin types, each defined by unique primary structures of the constant region of the heavy-chain molecule, and each with characteristic biological and functional properties. New methods and reagents to measure serum concentrations have contributed to the study of the ontogeny, antigen restriction, and ...
R J Wedgwood, H D Ochs
openaire   +3 more sources

Expanded phenotypes and outcomes among 256 LGI1/CASPR2‐IgG–positive patients

Annals of Neurology, 2017
To describe an expanded phenotypic spectrum and longitudinal outcome in 256 LGI1‐IgG–seropositive and/or CASPR2‐IgG–seropositive patients.
A. Gadoth   +12 more
semanticscholar   +1 more source

IgG/IgA Pemphigus

The American Journal of Dermatopathology, 2014
IgG/IgA pemphigus has recently been described in the literature as an overlap of pemphigus vulgaris or pemphigus foliaceus with IgA pemphigus. There has also been some postulation that this IgG/IgA pemphigus may be associated with internal malignancy as well.
Palak Parekh, Natalie Lane
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IgG glycosylation analysis

PROTEOMICS, 2009
AbstractA multitude of monoclonal IgG antibodies directed against a variety of therapeutic targets is currently being developed and produced by biotechnological companies. The biological activity of IgGs is modulated by the N‐glycans attached to the fragment crystallizable (Fc) part.
André M. Deelder   +4 more
openaire   +3 more sources

Clinical phenotype, radiological features, and treatment of myelin oligodendrocyte glycoprotein-immunoglobulin G (MOG-IgG) optic neuritis.

Current Opinion in Neurology, 2019
PURPOSE OF REVIEW To review the clinical characteristics, radiological manifestations and treatment of myelin oligodendrocyte glycoprotein (MOG)-immunoglobulin G (IgG) optic neuritis. RECENT FINDINGS Serum antibodies to MOG (MOG-IgG) have recently been
John J. Chen, M. T. Bhatti
semanticscholar   +1 more source

Citraconylated rabbit IgG

Molecular Immunology, 1974
Abstract Citraconic anhydride and ϵ-Amino hexanoic acid were reacted and ϵ,N-Citraconyl Aminocaproate (ENCTC) was prepared. The molar extinction coefficient of ENCTC at 280 nm = 116 M −1 , and at 241 nm = 7610 M −1 . These were used to determine the number of citraconyl groups covalently attached per mole of rabbit IgG. It was found that all free
openaire   +3 more sources

Electrophoretic heterogeneity of IgG

Clinica Chimica Acta, 1968
Abstract Electrophoretic heterogeneity of IgG populations with a mobility slower than β1 has been studied by analysing the quantitative immunoelectrophoresis patterns. The populations studied were arbitrarily subdivided in 3 ranges, slow (S), medium (M) and fast (F).
E. Afonso, J.S. Proenca
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