Results 51 to 60 of about 1,066,993 (308)

Futtermittel-spezifisches IgG und IgE vor und nach Eliminationsdiäten bei allergischen Hunden [PDF]

, 2012
Serum food allergen-specific antibody testing is widely offered to identify suitable ingredients for diets to diagnose adverse food reaction (AFR) in dogs with allergic skin disease.
Zimmer, Anja
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Comparative analysis of IgG levels in blood sera from patients with COVID-19, persons vaccinated by «Gam-COVID-Vac» and healthy donors before the pandemic

Журнал микробиологии, эпидемиологии и иммунобиологии, 2023
Introduction. Serum IgG measurement is used in the diagnosis and monitoring of many diseases. Therefore, it seems important to study the impact of coronavirus pandemic on IgG levels in population and the role of this parameter in COVID-19.
Yulia N. Tarakanova, Olga V. Borisova, Dmitriy A. Dmitriev, Maria V. Lichutina, Yulia S. Massino, Anastasia A. Pechelyulko, Olga L. Segal, Dinora A. Yakovleva, Alexander D. Dmitriev   +8 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Clinical characteristics of patients with GFAP-IgG coexisting with AQP4-IgG or MOG-IgG

Frontiers in Immunology
BackgroundGlial fibrillary acidic protein–immunoglobulin G (GFAP-IgG) can coexist with aquaporin-4–IgG (AQP4-IgG) or myelin oligodendrocyte glycoprotein–IgG (MOG-IgG). We aimed to investigate the clinical characteristics of patients with GFAP-IgG coexisting with AQP4-IgG or MOG-IgG.MethodsWe retrospectively collected data from 81 GFAP-IgG-positive ...
Qingchen Li, Xinyun Chen
openaire   +4 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Image_2_ST18 Enhances PV-IgG-Induced Loss of Keratinocyte Cohesion in Parallel to Increased ERK Activation.TIF

, 2019
Pemphigus is an autoimmune blistering disease targeting the desmosomal proteins desmoglein (Dsg) 1 and Dsg3. Recently, a genetic variant of the Suppression of tumorigenicity 18 (ST18) promoter was reported to cause ST18 up-regulation, associated with ...
Ofer Sarig (2697442), Eli Sprecher (251645), Mariya Y. Radeva (625707), Elias Walter (4975826), Jens Waschke (103956), Nicolas Schlegel (792185), Ramona Alexandra Stach (6595340), Amir S. Yazdi (245762)   +7 more
core   +1 more source

MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 4: Afferent visual system damage after optic neuritis in MOG-IgG-seropositive versus AQP4-IgG-seropositive patients [PDF]

, 2016
Background: Antibodies against myelin oligodendrocyte glycoprotein (MOG-IgG) have been reported in patients with aquaporin-4 antibody (AQP4-IgG)-negative neuromyelitis optica spectrum disorders (NMOSD).
Ringelstein, M., Gross, N., Ach, T., Janine Mikolajczak, Nikolai Gross (3411101), Buttmann, Mathias, Janine Mikolajczak (792945), Waldman, Amy, Friedemann Paul (25657), Markus Reindl, Thomas Ach, Paul, Friedemann, Brigitte Wildemann, Kerstin Soelberg, Schumacher, S., Orhan Aktas, Florence Pache (789593), Brandt, Alexander U, Bellmann-Strobl, Judith, Reindl, Markus, Florence Pache, Mathias Buttmann (239218), Waldman, A., Buttmann, Ma., Wildemann, B., Ruprecht, Klemens, Friedemann Paul, Kerstin Soelberg (3411095), Ringelstein, Marius, Schumacher, Sophie, null null, Amy Waldman (3411092), Oertel, F.C., Nasrin Asgari (3411086), Brandt, Alexander U., Nasrin Asgari, Anna Lacheta, Judith Bellmann-Strobl, Paul, F., Lacheta, A., Klemens Ruprecht, Sophie Schumacher (3411104), Wildemann, Brigitte, Soelberg, Kerstin, Judith Bellmann-Strobl (96062), Mikolajczak, Janine, Alexander Brandt (3411098), Reindl, M., Mathias Buttmann, Bellmann-Strobl, J., Ruprecht, K., Jarius, Sven, Sven Jarius (25658), Pache, F., Marius Ringelstein (171207), Anna Lacheta (3411107), Pache, Florence, Asgari, Nasrin, Mikolajczak, J., Oertel, Frederike C., Zimmermann, Hanna, Sophie Schumacher, Hanna Zimmermann (319981), Frederike Oertel (3411083), Aktas, Orhan, Asgari, N., Zimmermann, H., Gross, Nikolai, Alexander U. Brandt, Hanna Zimmermann, Klemens Ruprecht (187598), Thomas Ach (3411089), Aktas, O., Lacheta, Anna, Markus Reindl (89559), Nikolai Gross, Jarius, S., Marius Ringelstein, Orhan Aktas (25659), Soelberg, K., Brandt, A.U., Ach, Thomas, Sven Jarius, Amy Waldman, Frederike C. Oertel, Brigitte Wildemann (316416), Soelberg, Kerstin; id_orcid   +86 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Image_1_ST18 Enhances PV-IgG-Induced Loss of Keratinocyte Cohesion in Parallel to Increased ERK Activation.TIF

, 2019
Pemphigus is an autoimmune blistering disease targeting the desmosomal proteins desmoglein (Dsg) 1 and Dsg3. Recently, a genetic variant of the Suppression of tumorigenicity 18 (ST18) promoter was reported to cause ST18 up-regulation, associated with ...
Ofer Sarig (2697442), Eli Sprecher (251645), Mariya Y. Radeva (625707), Elias Walter (4975826), Jens Waschke (103956), Nicolas Schlegel (792185), Ramona Alexandra Stach (6595340), Amir S. Yazdi (245762)   +7 more
core   +1 more source