Results 111 to 120 of about 48,471 (314)

B‐Cell Repertoire of Children With Atopic Dermatitis Exhibits Altered IgE Maturation Associated With Allergic Food Sensitization

Allergy, EarlyView.
IgH repertoire sequencing of a large atopic dermatitis cohort reveal reduced IgE somatic hypermutation and increased IgE diversity associated with food allergen sensitization. Presence of a dog during the first year of life is associated with increased IgE somatic hypermutation, possibly countering the effect of food sensitization.
Kirandeep K. Gill, Carolina Moore, Onyekachi Nwogu, John W. Kroner, Wan‐Chi Chang, Jeffrey Burkle, Samuel J. Virolainen, Mariana L. Stevens, Asel Baatyrbek, Emily R. Miraldi, Jocelyn M. Biagini, Ashley L. Devonshire, Leah Kottyan, Justin T. Schwartz, Amal H. Assa'ad, Lisa J. Martin, Sandra Andorf, Gurjit K. Khurana Hershey, Krishna M. Roskin   +18 more
wiley   +1 more source

Long‐Term Effect of Allergen Immunotherapy in Responder Local Allergic Rhinitis Patients: Symptom Control, and Prevention of Asthma and Allergic Sensitizations

Allergy, EarlyView.
LAR patients who respond to AIT during the first year and are treated for two more years continue improving (less symptoms and medication intake) during the following seven years. AIT prevents the onset of asthma and allergic sensitizations in responder LAR individuals during the seven years following discontinuation.
Almudena Testera‐Montes, Laura Zubiaga‐Fernandez, Carlos J. Aranda, Irene Garcia‐Esteban, Trinidad Ilda Gaitan‐Nievas, Dulce Sanchez‐Torralvo, Cristobalina Mayorga, Maria J. Torres, Ibon Eguiluz‐Gracia, Carmen Rondon   +9 more
wiley   +1 more source

Recognizing Immunoglobulin G4-Related Overlap Syndromes in Patients with Pancreatic and Hepatobiliary Diseases

Canadian Journal of Gastroenterology, 2008
The first description of autoimmune pancreatitis and elevated serum immunoglobulin-G4 (IgG4) in 2001 heralded further reports of several related autoimmune diseases with raised IgG4 levels.
Aldo J Montano-Loza, Eoin Lalor, Andrew L Mason   +2 more
doaj   +1 more source

Decreased Severity of Oral Immunotherapy Induced Gastrointestinal Eosinophilic Reactions Following Revisions in Milk‐Treatment Protocol

Allergy, EarlyView.
A revised milk OIT protocol with lower daily allergen load and slower dose escalation reduced the severity and delayed onset of OIT‐induced gastrointestinal eosinophilic reactions (OITIGER). Elevated baseline absolute eosinophil count (AEC > 600/μL) was a consistent independent risk factor for OITIGER, while older age was protective.
Na'ama Epstein‐Rigbi, Matan Elkan, Yair Tzarfati, Michael B. Levy, Liat Nachshon, Yael Koren, Yitzhak Katz, Arnon Elizur, Michael R. Goldberg   +8 more
wiley   +1 more source

Phospholipase A2 receptor-negative membranous nephropathy presenting as a rare renal manifestation of IgG4-related disease

SAGE Open Medical Case Reports
IgG4-related disease is a fibroinflammatory condition characterized by dense lymphoplasmacytic infiltrates rich in IgG4-positive plasma cells affecting multiple organs.
Srikar Sama, Alexander Weickhardt, Preethi Subramanian, Pooja Reddy   +3 more
doaj   +1 more source

IgG4⁃related Mikulicz disease: a case report and literature review

口腔疾病防治, 2019
Objective To explore the etiology, clinical manifestations, diagnosis and treatment of IgG4⁃related Mi⁃ kulicz disease and to provide a reference for clinical diagnosis and treatment.
LUO Hao, MENG Jian
doaj   +1 more source

Oral Immunotherapy Induces Shift in lncRNA Expression Modulating Allergen‐Specific Immune Responses

Allergy, EarlyView.
We used PBMC transcriptome from 50 hen's egg‐allergic patients to study the role of lncRNA in OIT. Positive correlation was found between 17 lncRNAs and the IL‐4/IL‐13 pathway in vivo, and the expression of the selected lncRNA aligned with CXCL8 upon PBMC egg‐restimulation.
Olivia Liong, Kati Palosuo, Victoria Hinkkanen, Vittorio Fortino, Mika J. Mäkelä, Piia Karisola   +5 more
wiley   +1 more source

IgG4-related small-sized occlusive vasculitis in Mikulicz's disease

Journal of Vascular Surgery Cases and Innovative Techniques, 2019
Mikulicz's disease is one of the IgG4-related diseases (IgG4-RDs) that involves the cardiovascular system; however, small-sized vasculitis is rare in IgG4-related diseases.
Kuniyasu Ikeoka, MD, PhD, Tetsuya Watanabe, MD, PhD, Toshika Ohkawa, MD, PhD, Takashi Tsuzuki, MD, Yoshihiko Ikeda, MD, PhD, Masashi Takeda, MD, PhD, Shiro Hoshida, MD, PhD   +6 more
doaj   +1 more source

Basophil Activation Test as Biomarker of Severity and Threshold of Allergic Reactions to Cow's Milk During Oral Food Challenges

Allergy, EarlyView.
The threshold of reactivity during fresh milk challenges was 70% lower than that of baked milk challenges, reflecting the higher allergenicity of fresh milk. BAT was the only biomarker statistically significantly different between severity and threshold groups, for baked milk and fresh milk allergies, respectively.
Holly Boyd, Irene Bartha, Ru‐Xin Foong, Marta Krawiec, Andreina Marques‐Mejias, Hannah F. Marshall, Suzana Radulovic, Faye Harrison, Grammatiki Antoneria, Zainab Jama, Matthew Kwok, Ewa Pietraszewicz, Malak Eghleilib, Cristian Ricci, Tom Marrs, Gideon Lack, George Du Toit, Alexandra F. Santos   +17 more
wiley   +1 more source

Five‐Grass‐Pollen Sublingual Immunotherapy Drops Are Efficacious and Well Tolerated in Adults: The RHAPSODY Phase III Trial

Allergy, EarlyView.
The RHAPSODY multinational study investigated 26 months of continuous treatment with 5‐grass‐pollen sublingual SLIT drops in adults with moderate‐to‐severe grass‐pollen‐induced allergic rhinoconjunctivitis. The primary efficacy endpoint (the average daily total combined score) showed statistically significant differences in favour of the active ...
Alain Didier, Ruta Gronskyte Juhl, Terrie Dalgaard, Antoine Chartier, Philippe Devillier   +4 more
wiley   +1 more source