Results 91 to 100 of about 1,581,690 (305)

The future outlook on allergen immunotherapy in children: 2018 and beyond. [PDF]

, 2018
Allergen immunotherapy (AIT) is the only currently available immune-modifying and aetiological treatment for patients suffering from IgE-mediated diseases.
Arasi S, Corsello G, Pajno GB, Villani A
core   +2 more sources

IgG4-related disease: what a hematologist needs to know

Haematologica, 2019
IgG4-related disease is a fibro-inflammatory condition that can affect nearly any organ system. Common presentations include major salivary and lacrimal gland enlargement, orbital disease, autoimmune pancreatitis, retroperitoneal fibrosis and ...
Luke Y. C. Chen, A. Mattman, M. Seidman, M. Carruthers   +3 more
semanticscholar   +1 more source

Adverse immunostimulation in early phase clinical trials: Key findings and recommendations based on the investigator's clinical experience

British Journal of Clinical Pharmacology, EarlyView.
Problem setting The emergence of therapeutic proteins has coincided with an increase of acute adverse immunostimulation (AIS). AIS has occured in clinical trials despite compliance with regulatory guidelines on preclinical evaluation and its incidence is anticipated to increase even further.
Juliette A. van den Noort, Marella C. E. van Ruissen, Lisanne C. A. Smidt, Naomi B. Klarenbeek, Philip H. K. Kremer, Manon A. A. Jansen, Jacobus Burggraaf, Joop M. A. van Gerven, Matthijs Moerland   +8 more
wiley   +1 more source

A case of eosinophilic granulomatosis with polyangiitis complicated with a similar condition to IgG4 related lung disease

BMC Pulmonary Medicine, 2019
Background Atypical manifestations, such as elevated serum immunoglobulin-G4 (IgG4) and extra-pulmonary IgG4 positive plasmacyte infiltration, have been described in patients with eosinophilic granulomatosis with polyangiitis (EGPA), such complicated ...
Li Zhou, Fen Cao, Songqing Fan, Ping Chen, Shuizi Ding, Guiqian Liu, Ruoyun Ouyang   +6 more
doaj   +1 more source

Unclassified autoimmune pancreatitis mimicking pancreatic cancer [PDF]

, 2019
A 24-year-old black male presented with a 1-week obstructive jaundice and intermittent abdominal pain, with no significant weight loss and an unsuspicious abdominal exam.
Alves, A, Marinho, R, Nunes, V, Pignatelli, N   +3 more
core   +1 more source

Consumed by Abdominal Distention

Arthritis Care &Research, EarlyView.
Abimbola Fadairo‐Azinge, James Grenert, Brian Haas, Mary Margaretten   +3 more
wiley   +1 more source

A dose‐finding population pharmacokinetic/pharmacodynamic model of ginisortamab, an anti‐gremlin‐1 monoclonal antibody, in patients with solid tumours

British Journal of Clinical Pharmacology, EarlyView.
Aims Ginisortamab, a first‐in‐class human monoclonal antibody for the treatment of advanced solid tumours, binds to gremlin‐1 and restores bone morphogenetic protein signalling. We used pharmacokinetic/pharmacodynamic (PK/PD) modelling to characterize the relationship between ginisortamab dose and serum gremlin‐1 binding, using model‐based simulations ...
Yin Cheong Wong, Luisa Rojas Chavarro, Paul Jones, David Egging, Wanchana Ungphakorn, Marta Valle, Ivan Matthews   +6 more
wiley   +1 more source

Allergic Disorders in Africa and Africans: Is it Primarily a Priority? [PDF]

, 2010
In Africa, the burden of some diseases has been a problem for centuries. The spectrum of African diseases includes allergies, infections, nutritional deficiencies, and natural disasters.
Adams, Araujo, Araujo, Asmah, Breman, Brugman, Butler, Carvalho, Chaisson, Cooper, Cooper, Cooper, Cullinan, Dagoye, Dagoye, Du Toit, Erasto Vitus Mbugi, Estmbale, Gadermaier, Grant, Jaffu Othniel Chilongola, Jeannin, Jeebhay, Jeebhay, Kamradt, Linneberg, Linneberg, Lopata, Lynch, Lynch, Madsen, Marshall, Matricardi, Matricardi, Mercer, Modjarrad, Moore, Motala, Ndiaye, Nicolaou, Nyan, Obeng, Obihara, Obihara, Obihara, Obihara, Obihara, Obihara, Okano, Pacifico, Palyvos, Pawankar, Platts-Mills, Potter, Potter, Potter, Potter, Rauter, Riedler, Scrivener, Sibanda, Sibanda, Steinman, Thyssen, Tohon, van den Biggelaar, van den Biggelaar, van den Biggelaar, van der Kleij, van Niekerk, Van Niekerk, Veien, Veien, Vergara, Weinberg, Westritschnig, Wuthrich, Yazdanbakhsh, Yazdanbakhsh, Yazdanbakhsh, Zar   +80 more
core   +1 more source

A case report: Diagnosis and treatment of idiopathic hypertrophic pachymeningitis

Ibrain, Volume 11, Issue 1, Page 112-116, Spring 2025.
We reported a case of idiopathic hypertrophic dura meningitis diagnosed in our hospital. The patient repeatedly suffered from headaches, followed by blurred vision in the right eye. During this period, multiple sclerosis was considered for diagnosis, and it improved after hormone treatment.
Zhong Luo, Piao Cao, Jing‐Qing Xu, Rong Yan, Jian Wang, Tao Liang, Ya Chen, Zu‐Cai Xu   +7 more
wiley   +1 more source

A large‐scale single‐cell transcriptomic atlas indicates the immune panorama of influenza A infection

iMeta, EarlyView.
The study presents a large‐scale single‐cell transcriptomic atlas profiling over 612,010 peripheral immune cells from 97 individuals to decode the heterogeneity of influenza infection. These findings indicate a fundamental immune dichotomy determining clinical trajectories: a protective, monocyte‐centric antiviral state in mild disease versus a ...
Yi Wang, Shuzi Liu, Laurence Don Wai Luu, Yongzhi Zhai, Chenliang Zhu, Zhaomin Feng, Yao Tan, Linglong Wan, Jie Wang, Juan Zhou, Jing Wang, Lixin Xie, Quanyi Wang, Fei Xie   +13 more
wiley   +1 more source