Results 101 to 110 of about 1,581,690 (305)

CD4+ and CD8+ cytotoxic T lymphocytes may induce mesenchymal cell apoptosis in IgG4-related disease.

Journal of Allergy and Clinical Immunology, 2020
BACKGROUND IgG4-related disease (IgG4-RD) is an immune-mediated fibrotic disorder that has been linked to CD4+ cytotoxic T lymphocytes (CD4+CTLs). The effector phenotype of CD4+CTLs, the relevance of both CD8+ cytotoxic T lymphocytes (CD8+CTLs) and of ...
C. Perugino, N. Kaneko, T. Maehara, H. Mattoo, J. Kers, Hugues Allard-Chamard, V. Mahajan, Hang Liu, E. Della-Torre, Samuel J. H. Murphy, M. Ghebremichael, Z. Wallace, M. Bolster, Liam Harvey, G. Mylvaganam, Yesim Tuncay, L. Liang, S. Montesi, Xiuwei Zhang, Akira Tinju, Keita Mochizuki, Ryusuke Munemura, Mizuki Sakamoto, M. Moriyama, Seiji Nakamura, N. Yosef, J. Stone, S. Pillai   +27 more
semanticscholar   +1 more source

Clinical phenotypes of IgG4-related disease reflect different prognostic outcomes.

Rheumatology, 2020
INTRODUCTION Four clinical phenotypes of IgG4-related disease (IgG4-RD) have been recently identified by latent class analysis (LCA): pancreato-biliary (group 1); retroperitoneum/aortitis (group 2); head and neck limited (group 3); and Mikulicz/systemic (
M. Lanzillotta, C. Campochiaro, G. Mancuso, G. Ramirez, G. Capurso, M. Falconi, L. Dagna, E. Della-Torre   +7 more
semanticscholar   +1 more source

IgG4-sclerosing cholangitis masquerading as cholangiocarcinoma: a case report of an unresolved preoperative diagnosis

Frontiers in Immunology
BackgroundImmunoglobulin G4-related disease (IgG4-RD) is an immune-mediated chronic fibroinflammatory condition that can affect multiple organ systems. IgG4-related sclerosing cholangitis (IgG4-SC) is its manifestation involving the biliary tract. Due to
Ying-Ao Liu, Xiang Gao, Wei Gao, Zeliang Hu, Fangzhou Wang, Yuanxu Qu, Yamin Zheng   +6 more
doaj   +1 more source

IgG4-Related Arterial Disease

Annals of Vascular Diseases, 2018
Immunoglobulin G4-related diseases (IgG4-RD) are systemic inflammatory conditions, characterized by high serum IgG4 concentrations, and pathologically IgG4-positive plasmacytes infiltrations and storiform fibrosis. We described IgG4-related inflammatory abdominal aortic aneurysm in 2008, and revealed the existence of vascular lesions.
Kasashima, Fuminori, Kawakami, Kengo, Matsumoto, Yasushi, Endo, Masamitsu, Kasashima, Satomi, Kawashima, Atsuhiro   +5 more
openaire   +3 more sources

Novel Laboratory Approaches in Heavy Chain Disease With Discordant Immunoglobulin Quantitation: A Case Report and Literature Review

Journal of Clinical Laboratory Analysis, EarlyView.
In this study, we investigated a rare case of γ‐heavy chain disease (γ‐HCD) through an integrated laboratory approach. Routine protein analyses (serum protein electrophoresis, immunotyping, and serum/urine immunofixation) identified an IgG monoclonal component without detectable light chains.
Eleonora Longhi, Artan Çeka, Fabiola Olivieri, Marco Moretti, Jacopo Sabbatinelli   +4 more
wiley   +1 more source

Neurological Manifestations of IgG4-Related Disease [PDF]

, 2017
IgG4-related disease (IgG4-RD) is a multisystem inflammatory disorder. Early recognition of IgG4-RD is important to avoid permanent organ dysfunction and disability.
Baptista, Bernardo, Casian, Alina, D'Cruz, David, Gunawardena, Harsha, Rice, Claire M   +4 more
core   +2 more sources

IgG4-related respiratory disease [PDF]

Modern Rheumatology, 2019
IgG4-related diseases (IgG4-RDs), such as autoimmune pancreatitis and IgG4-related Mikulicz disease, are often accompanied by intrathoracic lesions, which are called IgG4-related respiratory disease (IgG4-RRD). IgG4-RRD has few subjective symptoms, and is usually detected during workup of patients with extra-thoracic lesions of IgG4-RD.
openaire   +2 more sources

Late Onset Telomere Biology Disorder Presenting With Pancytopenia, Immune Dysregulation, Interstitial Lung Disease and Alopecia

American Journal of Hematology, EarlyView.
Bo A. Wan, Hamish Nicolson, Heather A. Leitch, Ryan J. Stubbins, Luke Y. C. Chen, Timothy Murray, Amy Trottier, Anthony Gador   +7 more
wiley   +1 more source

Long‐Term Outcomes and Predictors of Delayed Steroid Initiation in Type 1 Autoimmune Pancreatitis Initially Managed Without Corticosteroids

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background/Purpose Although type 1 autoimmune pancreatitis (AIP) responds well to corticosteroids, spontaneous remission can also occur. This study evaluated long‐term outcomes and predictors of delayed steroid initiation in AIP patients initially managed conservatively.
Yasuhiro Kuraishi, Akira Nakamura, Masafumi Minamisawa, Takumi Yanagisawa, Chinatsu Yonekura, Nobukazu Sasaki, Shunsuke Imamura, Takefumi Kimura, Yugo Iwaya, Tadanobu Nagaya   +9 more
wiley   +1 more source

Clinical Manifestations and Long-term Outcomes of IgG4-Related Kidney and Retroperitoneal Involvement in a United Kingdom IgG4-Related Disease Cohort

Kidney International Reports, 2019
Introduction: IgG4-related disease (IgG4-RD) is a relapsing multisystem fibro-inflammatory disease, which may involve the kidney (IgG4-related kidney disease [IgG4-RKD]) and retroperitoneum (IgG4-related retroperitoneal fibrosis [IgG4-RPF]).
Rhys D.R. Evans, Tamsin Cargill, George Goodchild, Ben Oliveira, Manuel Rodriguez-Justo, Ruth Pepper, John Connolly, Alan Salama, George Webster, Eleanor Barnes, Emma L. Culver   +10 more
doaj   +1 more source