Results 81 to 90 of about 1,581,690 (305)

Factors in glucocorticoid regimens associated with treatment response and relapses of IgG4-related disease: a multicentre study [PDF]

, 2018
Glucocorticoids (GC) are effective for treating IgG4-related disease (IgG4-RD); however, relapse is often observed. We conducted a retrospective multicentre study to investigate risk factors in GC regimens associated with relapses of IgG4-RD. Data on 166
Chiba Tsutomu, Goto Hiroshi, Hirata Shintaro, Ito Tetsuya, Kamisawa Terumi, Kawa Shigeyuki, Kawano Mitsuhiro, Kodama Yuzo, Matsui Shoko, Mimori Tsuneyo, Moriyama Masafumi, Nakamura Seiji, Okazaki Kazuichi, Sato Yasuharu, Shibata Motoko, Shirakashi Mirei, Sumida Takayuki, Takahashi Hiroki, Tanaka Yoshiya, Tsuboi Hiroto, Uchida Kazushige, Yamada Kazunori, Yamamoto Motohisa, Yoshifuji Hajime, Yoshino Tadashi, 住田 孝之, 坪井 洋人   +26 more
core   +2 more sources

Congruent microbiome signatures in fibrosis-prone autoimmune diseases: IgG4-related disease and systemic sclerosis

Genome Medicine, 2021
Immunoglobulin G4-related disease (IgG4-RD) and systemic sclerosis (SSc) are rare autoimmune diseases characterized by the presence of CD4+ cytotoxic T cells in the blood as well as inflammation and fibrosis in various organs, but they have no ...
D. Plichta, J. Somani, M. Pichaud, Z. Wallace, Ana D. Fernandes, C. Perugino, H. Lähdesmäki, J. Stone, H. Vlamakis, D. Chung, D. Khanna, S. Pillai, R. Xavier   +12 more
semanticscholar   +1 more source

The association of recurrent stroke and immunoglobulin G4-related arteritis in the central nervous system: a case report

Journal of Stroke and Cerebrovascular Diseases
Background: Immunoglobulin G4–related disease (IgG4-RD) is a systemic immune-mediated fibroinflammatory disease. Histopathology is the key to diagnosis.
Qi Huang, Hongjian Shen, Pengfei Xing, Yi Jiang, Xiaolong Xu, Qiang Li, Yongwei Zhang   +6 more
doaj   +1 more source

Multisystem IgG4-related disease involving the abdomen and coronary arteries and causing chronic abdominal pain

Acta Radiologica Open, 2021
IgG4-related disease was originally discovered in patients with autoimmune pancreatitis accompanied by elevated serum IgG4 levels and has subsequently been described in almost every organ system.
Nam Ju Lee, James F Glockner
doaj   +1 more source

Case Report: IgG4-related kidney disease complicated by interstitial pneumonia [version 1; peer review: 1 approved, 2 approved with reservations]

F1000Research, 2023
Immunoglobulin G4 (IgG4)-related disease is a systemic inflammatory disorder characterized by tubulointerstitial nephritis with IgG4-positive plasma cell infiltration.
Akira Mima, Shinji Lee, Hidemasa Gotoda, Ryosuke Akai, Rina Lee, Ami Murakami   +5 more
doaj   +1 more source

Anti-programmed cell death protein-1/ligand-1 therapy in different cancers. [PDF]

, 2015
Immunologic checkpoint blockade with antibodies against the programmed cell death protein-1 (PD-1) or its ligand (PD-L1) is an effective method for reversing cancer immunosuppression and thereby promoting immune responses against several cancer types ...
Homet Moreno, B, Ribas, A
core   +2 more sources

Local Specific IgE Levels Can Predict and Monitor the Therapeutic Response to Subcutaneous Immunotherapy With House Dust Mite

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Identifying predictive and monitoring biomarkers for allergen immunotherapy response is crucial for enhancing clinical efficacy. This study aims to investigate the systemic and local levels of immunoglobulins and identify potential biomarkers in house dust mite (HDM) allergic rhinitis (AR) patients who are undergoing subcutaneous ...
Xu Xu, Jingyun Li, Xu Zhang, Yu Song, Lin Xi, Luo Zhang, Yuan Zhang   +6 more
wiley   +1 more source

IgG4-related disease: A systematic review of this unrecognized disease in pediatrics [PDF]

, 2016
Background: Immunoglobulin G4-related disease (IgG4-RD) is a systemic fibro-inflammatory condition with an unclear pathophysiological mechanism affecting different parts of the body.
Bramer, W.M. (Wichor), Hagen, P.M. (Martin) van, Karim, A.F. (Faiz), Laar, J.A.M. (Jan) van, Loeffen, J. (Jan), Verdijk, R.M. (Robert), Westenberg, L. (Lauren)   +6 more
core   +4 more sources

IgG4 autoantibodies and autoantigens in the context of IgG4-autoimmune disease and IgG4-related disease

Frontiers in Immunology
Immunoglobulins are an essential part of the humoral immune response. IgG4 antibodies are the least prevalent subclass and have unique structural and functional properties. In this review, we discuss IgG4 class switch and B cell production. We review the
Rodrigo V Motta, E. Culver
semanticscholar   +1 more source

Interleukin‐5, Eosinophils, and Interleukin‐5 Pathway Inhibitors in Eosinophilic Granulomatosis With Polyangiitis

Arthritis &Rheumatology, EarlyView.
Interlukin‐5 (IL‐5) plays a crucial role in the pathogenesis of eosinophilic granulomatosis with polyangiitis (EGPA) by promoting eosinophil differentiation, activation, and survival. We present here a typical case of EGPA in which treatment with IL‐5 pathway inhibitors is prescribed, showing to be beneficial for the patient.
Alvise Berti, Christian Pagnoux
wiley   +1 more source