Results 161 to 170 of about 13,032,569 (265)

Neurologic IgG4-Related Disease [PDF]

The Neurohospitalist, 2018
Karan, Topiwala, Christopher, Hampton, Carl, Boland, David, Waitzman   +3 more
openaire   +2 more sources

Population Pharmacokinetics and Exposure–Response of Sasanlimab, a Checkpoint Inhibitor, in Patients with Non‐Muscle Invasive Bladder Cancer and Other Solid Tumors

The Journal of Clinical Pharmacology, Volume 66, Issue 9, September 2026.
Abstract Sasanlimab is a monoclonal antibody (mAb) which blocks human programed cell death protein 1. It is administered subcutaneously (SC), currently under development for non‐muscle invasive bladder cancer (NMIBC) with a recommended flat dose of 300 mg every 4 weeks (Q4W).
Joanna C. Masters, Brian Jermain, Alan Liu, Rossano Cesari, Anna Maria Calella, Elisabete Michelon, Caimiao Wei, Susana Liu, Joseph Piscitelli   +8 more
wiley   +1 more source

Unique Features of Nasal Airway and Airflow Improvement Post‐Dupilumab: A Computational Cohort Study

The Laryngoscope, Volume 136, Issue 9, Page 3744-3751, September 2026.
The impact of dupilumab on nasal airway patency and airflow is not uniform. It is more pronounced in the middle and superior, but not inferior meatus. These unique regional changes significantly correlate with and potentially drive the improvement in patient symptoms.
Ahmad Odeh, Zhenxing Wu, Nidhi Jha, Aspen R. Schneller, James Mihalich, Zachary T. Root, Christopher Brooks, Casey Curtis, Monica Kraft, Kara Wada, Bradley A. Otto, Kathleen M. Kelly, Kai Zhao   +12 more
wiley   +1 more source

IgG4-related disease has a specific intestinal microbiota signature. [PDF]

EBioMedicine
Budzinski L, Beenken AE, Sempert T, Kang GU, Abbas A, Lietz L, Maier R, Mashreghi MF, Chang HD, Alexander T.   +9 more
europepmc   +1 more source

Muscle‐Specific Kinase Signaling and Its Therapeutic Potential

Muscle &Nerve, Volume 74, Issue S1, Page S65-S75, September 2026.
ABSTRACT The function of the neuromuscular junction (NMJ) is compromised in many neuromuscular diseases (NMDs) such as autoimmune or congenital myasthenia gravis (MG), amyotrophic lateral sclerosis (ALS), spinal muscular atrophy (SMA), and muscular dystrophies.
Stine Marie Jensen, Dana L. E. Vergoossen, Maartje G. Huijbers   +2 more
wiley   +1 more source

IgG Subclass (IgG1‐4) and IgA Autoantibody Profiles Against Muscle‐Specific Kinase in a Greek Cohort

Muscle &Nerve, Volume 74, Issue S1, Page S132-S141, September 2026.
ABSTRACT Introduction/Aims Muscle‐specific kinase myasthenia gravis (MuSK‐MG) is an autoimmune neuromuscular disorder predominantly mediated by IgG4 autoantibodies disrupting MuSK signaling. The contribution of other isotypes remains incompletely defined. We characterized the serological profile of a Greek cohort of MuSK‐MG patients.
Sofia‐Natsοuko Gkotzamani, Maria Pechlivanidou, Francisca Faber, Cansu Elmas, Vasiliki Zouvelou, Elisabeth Chroni, Dimitrios Tzanetakos, Maria Kourouvani, Marlene Wolfsgruber, Ioannis Zaganas, Dimitra Kolovou, Michael Rentzos, Ariadne Daponte, Maria Chondrogiorgi, Spyridon Konitsiotis, Georgios Nicolaou, Stavroula Salakou, Sotirios Giannopoulos, Konstandinos Lazaridis, Georgios Tsivgoulis, Socrates Tzartos, Inga Koneczny, John S. Tzartos   +22 more
wiley   +1 more source

[Autoimmune pancreatitis and IgG4-related disease]. [PDF]

Inn Med (Heidelb)
Kleger A.
europepmc   +1 more source

Optimization of the Cell‐Based Assay Methodology to Study Degradation of Acetylcholine Receptors (Antigenic Modulation) by Antibodies From Myasthenia Gravis Patients

Muscle &Nerve, Volume 74, Issue S1, Page S150-S158, September 2026.
ABSTRACT Introduction/Aims Degradation of cell‐surface acetylcholine receptors (AChRs) by antigenic modulation is a key pathogenic mechanism of myasthenia gravis (MG) autoantibodies, yet standard assays primarily detect antibody binding rather than functional effects.
Peng Du, Marina Mané‐Damas, Fien M. Verhamme, Mahan Moshir, Peter Ulrichts, Barbie Machiels, Mario Losen, Pilar Martinez‐Martinez   +7 more
wiley   +1 more source

Case Report: IgG4-related disease presenting with prominent oculomotor nerve palsy. [PDF]

Front Neurol
Yu L, Huang W, Xu Y, Zhang C, Lv H, Lei W.   +5 more
europepmc   +1 more source

Granzyme K: A new frontier in systemic lupus erythematosus

Rheumatology &Autoimmunity, Volume 6, Issue 3, Page 160-168, September 2026.
The role of Granzyme K in the pathogenesis of systemic lupus erythematosus and its clinical translational significance. Abstract Systemic lupus erythematosus (SLE) is a complex autoimmune disorder driven by dysregulated adaptive and innate immunity and aberrant complement activity.
Zhongyu Chen, Yunjing Pu, Peihui Yang, Qinghuan Zhu, Haojun Long, Danqi Deng   +5 more
wiley   +1 more source