Results 181 to 190 of about 13,032,569 (265)
Proof-of-concept study: longitudinal immune biomarker signatures in treatment-naïve IgG4-related disease. [PDF]
Lopez-Gomez M +13 more
europepmc +1 more source
Integrated Engineering of CAR‐T Cells for Solid Tumours
Solid tumours pose multifactorial barriers including antigen heterogeneity, immunosuppressive microenvironment, and poor T‐cell trafficking, limiting CAR‐T efficacy compared to hematologic malignancies. Integrated engineering strategies are essential, combining logic‐gated receptors for precision, metabolic‐epigenetic reprogramming for resilience, and ...
Chao Yang +5 more
wiley +1 more source
ABSTRACT Background The therapeutic landscape of generalised myasthenia gravis (gMG) has evolved substantially with the approval of targeted immunotherapies, including complement C5 inhibitors (C5‐I) and neonatal Fc receptor inhibitors (FcRn‐I). While pivotal trials have demonstrated marked efficacy in defined subgroups, real‐world experience reveals ...
Andreas Meisel +17 more
wiley +1 more source
Niloufar Ebrahimi +8 more
openaire +2 more sources
This review highlights changes relevant to pathologists in the updated multidisciplinary classification of interstitial pneumonias. Changes include expansion beyond idiopathic disease, subclassification as interstitial (fibrotic vs non‐fibrotic) and alveolar filling disorders, expansion to include additional patterns (e.g.
Andrew G Nicholson +7 more
wiley +1 more source
Hearing the Unusual: A Rare Otological Case of IgG4-Related Disease Treated With Steroids and Inebiluzmab. [PDF]
Peng Y, Zaheer M.
europepmc +1 more source
Treatment Goals for Primary Biliary Cholangitis, an Australian Perspective
ABSTRACT Primary biliary cholangitis (PBC) is an autoimmune liver disease that targets the small intrahepatic bile ducts with diagnosis based on elevated serum alkaline phosphatase (ALP) levels and the presence of anti‐mitochondrial antibodies. Untreated, it may run a progressive course to cirrhosis and hepatic decompensation, at which point liver ...
Simone I. Strasser +6 more
wiley +1 more source
VEXAS Syndrome and IgG4-Related Disease: Coincidental Association or Pathogenetic Link? [PDF]
Kobak S +4 more
europepmc +1 more source
IgG4-related disease presenting as a gastric mass necessitating total gastrectomy: a case report. [PDF]
Jiwane M +6 more
europepmc +1 more source
Update on biologic and small molecules treatments in pediatric allergic diseases
This graphical abstract summarizes key targets, mechanisms of action, and indications of biologic and small molecules treatments in pediatric allergic diseases.abbreviations : BAS, basophil; BTK, Bruton tyrosine kinase; cDC, conventional dendritic cell; IgE, immunoglobulin E; FCER1, high affinity IgE receptor; IL, interleukin; IL4R, IL4 receptor; JAK ...
Herman T. den Dekker +10 more
wiley +1 more source

