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An atypical case of isolated immunoglobulin G4-related sclerosing cholangitis with a cholangiogram resembling primary sclerosing cholangitis [PDF]

open access: yes
An asymptomatic 77-year-old man with intrahepatic bile duct dilation was referred to our hospital. Cholangiography revealed alternations between strictures and dilated segments from the right and left hepatic ducts to the lower bile ducts, with findings ...
Iida, Tadashi   +6 more
core   +2 more sources

Clinical Practice Guidelines for Peroral Cholangioscopy

open access: yesJournal of Hepato-Biliary-Pancreatic Sciences, Volume 33, Issue 1, Page 58-71, January 2026.
Nagai and colleagues present evidence‐based clinical practice guidelines developed by the Japan Biliary Association to support the use of peroral cholangioscopy. The guidelines address indications, procedural standards, diagnostic and therapeutic applications, and adverse event management, providing a practical reference for the safe and effective use ...
Kazumasa Nagai   +13 more
wiley   +1 more source

A young patient with biliary and urinary disease: What's the unifying diagnosis?

open access: yesHong Kong Journal of Emergency Medicine, Volume 32, Issue 6, December 2025.
Abstract Introduction Chronic ketamine abuse is a growing public health concern associated with severe organ damage. While ketamine‐induced uropathy and cholangiopathy are well‐documented complications individually, their simultaneous presentation is rare. This dual‐system involvement, however, provides a key diagnostic clue on imaging.
Chung‐Wai Wong, Ho‐Nam Ho
wiley   +1 more source

Role of Peroral Cholangioscopy in the Diagnosis of Primary Sclerosing Cholangitis

open access: yesDiagnostics, 2020
Primary sclerosing cholangitis (PSC) is characterized by idiopathic biliary stricture followed by progressive cholestasis and fibrosis. When diagnosing PSC, its differentiation from other types of sclerosing cholangitis and cholangiocarcinoma is ...
Toshio Fujisawa   +11 more
doaj   +1 more source

Clinical perspectives and comparisons between immunoglobulin G4‐related disease and antineutrophil cytoplasmic antibody‐associated vasculitis

open access: yesRheumatology &Autoimmunity, Volume 5, Issue 4, Page 267-274, December 2025.
Clinical perspectives and comparisons between immunoglobulin G4‐related disease and antineutrophil cytoplasmic antibody‐associated vasculitis. Abstract Both immunoglobulin G4‐related disease (IgG4‐RD) and antineutrophil cytoplasmic antibody (ANCA)‐associated vasculitis (AAV) are systemic disorders that affect a wide range of organs.
Wenhuan Zeng, Mingxin Bai, Yanying Liu
wiley   +1 more source

IgG4-Producing MALT Lymphoma in the Renal Hilum

open access: yesCase Reports in Oncology, 2019
IgG4-related disease is diagnosed when both the elevation of the serum IgG4 level and invasion of IgG4-positive interstitial cells and sclerosis to a tumor are noted. Some cases have demonstrated malignant disease.
Kota Shimokihara   +7 more
doaj   +1 more source

Vendor‐Agnostic Vision Transformer‐Based Artificial Intelligence for Peroral Cholangioscopy: Diagnostic Performance in Biliary Strictures Compared With Convolutional Neural Networks and Endoscopists

open access: yesDigestive Endoscopy, Volume 37, Issue 12, Page 1315-1322, December 2025.
ABSTRACT Objectives Accurate diagnosis of biliary strictures remains challenging. This study aimed to develop an artificial intelligence (AI) system for peroral cholangioscopy (POCS) using a Vision Transformer (ViT) architecture and to evaluate its performance compared to different vendor devices, conventional convolutional neural networks (CNNs), and ...
Ryosuke Sato   +15 more
wiley   +1 more source

Diagnostic Utility of Liver Biopsy in Persistent Unexplained Liver Enzyme Elevation: A Retrospective Cohort Study

open access: yesJGH Open, Volume 9, Issue 11, November 2025.
ABSTRACT Background and Aims Chronically elevated liver enzymes without a clear etiology remain a frequent diagnostic challenge. This study evaluated the diagnostic yield of liver biopsy in such cases and assessed if laboratory parameters predict histological clarification. Methods We retrospectively analyzed 71 patients with unexplained elevated liver
S. Jaawan   +8 more
wiley   +1 more source

IgG4-related sclerosing cholangitis: liver biopsy findings

open access: yesThe Korean Journal of Hepatology, 2011
IgG4-related autoimmune disease is a recently recognized clinical entity associated with autoimmune pancreatitis, various systemic extrapancreatic lesions and an elevated serum IgG4 level.1 IgG4-related sclerosing cholangitis (IgG4-SC) is one of the extrapancreatic manifestations of this entity, which needs to be differentiated from primary sclerosing ...
Ryu, Han Suk, Kim, Haeryoung
openaire   +2 more sources

Tepotinib‐Induced Cholangitis in a Patient With Non‐Small Cell Lung Cancer: A Case Report

open access: yesRespirology Case Reports, Volume 13, Issue 11, November 2025.
Here, we report the first case of tepotinib‐induced cholangitis. When using MET inhibitors for chemotherapy, attention should be paid not only to treatment effectiveness but also to possible hepatobiliary side effects. ABSTRACT Tepotinib, a mesenchymal epithelial transition factor (MET) tyrosine kinase inhibitor, is used to treat non‐small cell lung ...
Yoshimasa Hachisu   +7 more
wiley   +1 more source

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